D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period.

Autor: Claire N J Meunier, Glenn Dallérac, Nicolas Le Roux, Silvia Sacchi, Grégoire Levasseur, Muriel Amar, Loredano Pollegioni, Jean-Pierre Mothet, Philippe Fossier

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151233 (2016)

N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity. Their activation requires the binding of both glutamate and d-serine or glycine as co-agonist. The prevalence of either co-agonist on NMDA-receptor function differs b

Externí odkaz: https://doaj.org/article/7c11df82b42642e79060639c47e44527

Nitric Oxide and l-Arginine Cause an Accumulation of Utrophin at the Sarcolemma: A Possible Compensation for Dystrophin Loss in Duchenne Muscular Dystrophy

Autor: Emmanuel Chaubourt, Philippe Fossier, Gérard Baux, Christine Leprince, Maurice Israël, Sabine De La Porte

Publikováno v: Neurobiology of Disease, Vol 6, Iss 6, Pp 499-507 (1999)

Duchenne muscular dystrophy (DMD), a severe X-linked recessive disorder which results in progressive muscle degeneration, is due to a lack of dystrophin, a membrane cytoskeletal protein. An approach to treatment is to compensate for dystrophin loss w

Externí odkaz: https://doaj.org/article/d2300b663fb94273a070a27c8d8b0df5

A multiscale analysis in CD38 −/− mice unveils major prefrontal cortex dysfunctions

Autor: José-Manuel Cancela, Oscar Bauer, Jean-Marc Edeline, Gabriel Benet, Antoine De Zelicourt, Catherine Sebrié, Cyrille Vaillend, Muriel Amar, Sabine De La Porte, Antony Galione, Philippe Fossier, Lora L Martucci, Anne Nosjean, Jacques Callebert, Rémi Chaussenot, Sylvie Granon, Jean-Marie Launay

Publikováno v: FASEB Journal
FASEB Journal, 2019, 54, pp.fj.201800489R. ⟨10.1096/fj.201800489R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2019, 54, pp.fj.201800489R. ⟨10.1096/fj.201800489R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2019, 33 (5), pp.5823-5835. ⟨10.1096/fj.201800489R⟩

International audience; Autism spectrum disorder (ASD) is characterized by early onset of behavioral and cognitive alterations. Low plasma levels of oxytocin (OT) have also been found in ASD patients; recently, a critical role for the enzyme CD38 in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6302ec700c2754cce805314269bdb029
https://doi.org/10.1096/fj.201800489r

Dp71-Dystrophin Deficiency Alters Prefrontal Cortex Excitation-Inhibition Balance and Executive Functions

Autor: Muriel Amar, Rémi Chaussenot, Cyrille Vaillend, Philippe Fossier

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2018, ⟨10.1007/s12035-018-1259-6⟩
Molecular Neurobiology, 2018, ⟨10.1007/s12035-018-1259-6⟩

International audience; In the Duchenne muscular dystrophy (DMD) syndrome, mutations affecting expression of Dp71, the main dystrophin isoform of the multipromoter dmd gene in brain, have been associated with intellectual disability and neuropsychiat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1c46aa84b2bbec7755a668543150d9
https://pubmed.ncbi.nlm.nih.gov/30051354

Lack of GSK3β activation and modulation of synaptic plasticity by dopamine in 5-HT1A-receptor KO mice

Autor: Philippe Fossier, José-Manuel Cancela, Claire Nicole-Jeanne Meunier

Publikováno v: Neuropharmacology
Neuropharmacology, Elsevier, 2016, 113, pp.124-136. ⟨10.1016/j.neuropharm.2016.09.025⟩

International audience; Psychiatric disorders are associated with excitation-inhibition (E-I) balance impairment in the prefrontal cortex. However, how the E-I balance is regulated is poorly known. The E-I balance of neuronal networks is linked to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab92295d24f7e95f222914cc8a6062d
https://pubmed.ncbi.nlm.nih.gov/27678414