RNA Structural Requirements for Nucleocapsid Protein-Mediated Extended Dimer Formation

Autor: Françoise Chaminade, Jean-Luc Darlix, Philippe Fossé

Publikováno v: Viruses, Vol 14, Iss 3, p 606 (2022)

Retroviruses package two copies of their genomic RNA (gRNA) as non-covalently linked dimers. Many studies suggest that the retroviral nucleocapsid protein (NC) plays an important role in gRNA dimerization. The upper part of the L3 RNA stem-loop in th

Externí odkaz: https://doaj.org/article/2e17053a5a3442adb8152cb5a0616a67

Intrinsic nucleic acid dynamics modulates HIV-1 nucleocapsid protein binding to its targets.

Autor: Ali Bazzi, Loussiné Zargarian, Françoise Chaminade, Hugues De Rocquigny, Brigitte René, Yves Mély, Philippe Fossé, Olivier Mauffret

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38905 (2012)

HIV-1 nucleocapsid protein (NC) is involved in the rearrangement of nucleic acids occurring in key steps of reverse transcription. The protein, through its two zinc fingers, interacts preferentially with unpaired guanines in single-stranded sequences

Externí odkaz: https://doaj.org/article/4daf88b01b9443528384150c085154af

Salvage anastomosis in free PAP-flap breast reconstruction: What about free flap neovascularization?

Autor: Michaël Hepp, Aline Berners, Christine Deconinck, Genevieve Pirson, Maxime Servaes, Philippe Fosseprez

Publikováno v: Chinese Journal of Plastic and Reconstructive Surgery, Vol 5, Iss 4, Pp 178-181 (2023)

Since the emergence of microsurgery in reconstructive surgery, free flaps have become a key tool in the management of patients with breast cancer. One such flap is the profunda artery perforator (PAP) flap. To date, there is no scientific consensus o

Externí odkaz: https://doaj.org/article/a9fe5bd467734c1eb8081f07f9327027

SurLym trial: study protocol for a multicentre pragmatic randomised controlled trial on the added value of reconstructive lymphatic surgery to decongestive lymphatic therapy for the treatment of lymphoedema

Autor: Nele Devoogdt, Lode Godderis, Sarah Thomis, Beate Bechter-Hugl, Inge Fourneau, Steffen Fieuws, Geert Maleux, Daniel Devos, Thierry Deltombe, Tessa De Vrieze, An-Kathleen Heroes, Katarina Segers, Jacqueline Frippiat, Maxime Servaes, Aline Berners, Philippe Fosseprez, Bruno Krug, Francoise Kayser, Ana Falticeanu, Caren Randon, Chris Monten, Koen Van Landuyt, Bernard De Pypere, Liesl Degraeve, Tina Decorte, Mieke De Schryver, Vickie Van Besien, Sinikka Suominen, Jaume Masia Ayala, Gemma Pons

Publikováno v: BMJ Open, Vol 14, Iss 5 (2024)

Introduction Lymphoedema is a chronic condition caused by lymphatic insufficiency. It leads to swelling of the limb/midline region and an increased risk of infection. Lymphoedema is often associated with mental and physical problems limiting quality

Externí odkaz: https://doaj.org/article/20b0751838bc4bcca6404b6bff26dd72

Analysis of hepatitis C virus RNA dimerization and core–RNA interactions

Autor: Igor Kanevsky, Philippe Fossé, Jean-Pierre Lavergne, Jean-Luc Darlix, François Penin, Caroline Gabus, Roland Ivanyi-Nagy, Damien Ficheux

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2006, 34 (9), pp.2618-33. ⟨10.1093/nar/gkl240⟩
Nucleic Acids Research, 2006, 34 (9), pp.2618-33. ⟨10.1093/nar/gkl240⟩

The core protein of hepatitis C virus (HCV) has been shown previously to act as a potent nucleic acid chaperone in vitro, promoting the dimerization of the 3'-untranslated region (3'-UTR) of the HCV genomic RNA, a process probably mediated by a small

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149c2d81b7b633649e287748bc7a5b21
http://europepmc.org/articles/PMC1463901