Pediatric Formulations Developed by Extrusion-Based 3D Printing: From Past Discoveries to Future Prospects

Autor: Veronica Ianno, Sarah Vurpillot, Sylvain Prillieux, Philippe Espeau

Publikováno v: Pharmaceutics, Vol 16, Iss 4, p 441 (2024)

Three-dimensional printing (3DP) technology in pharmaceutical areas is leading to a significant change in controlled drug delivery and pharmaceutical product development. Pharmaceutical industries and academics are becoming increasingly interested in

Externí odkaz: https://doaj.org/article/c55fcce5c121410f87045cfaa27b750b

New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

Autor: Panpan Ma, Balthazar Toussaint, Enrica Angela Roberti, Noémie Scornet, Axel Santos Silva, Luis Castillo Henríquez, Monique Cadasse, Philippe Négrier, Stéphane Massip, Hanh Dufat, Karim Hammad, Cecilia Baraldi, Maria Cristina Gamberini, Cyrille Richard, Stéphane Veesler, Philippe Espeau, Tu Lee, Yohann Corvis

Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1102 (2023)

This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal. For that purpose, two new 1:1 cocrystals, namely lidocaine:dl-menthol and

Externí odkaz: https://doaj.org/article/918472ae97374451bf769c5212819eaa

Co-Encapsulation of Fisetin and Cisplatin into Liposomes for Glioma Therapy: From Formulation to Cell Evaluation

Autor: Morgane Renault-Mahieux, Victoire Vieillard, Johanne Seguin, Philippe Espeau, Dang Tri Le, René Lai-Kuen, Nathalie Mignet, Muriel Paul, Karine Andrieux

Publikováno v: Pharmaceutics, Vol 13, Iss 7, p 970 (2021)

(1) Background: Glioblastoma (GBM) is the most frequent cerebral tumor. It almost always relapses and there is no validated treatment for second-line GBM. We proposed the coencapsulation of fisetin and cisplatin into liposomes, aiming to (i) obtain a

Externí odkaz: https://doaj.org/article/5aaaee7781b34eb0bb2cb81014ea6d34

Evidence of a New Crystalline Phase of Prednisolone Obtained from the Study of the Hydration–Dehydration Mechanisms of the Sesquihydrate

Autor: Coquerel, Aurélien Lemercier, Nicolas Couvrat, Yohann Cartigny, Morgane Sanselme, Yohann Corvis, Philippe Espeau, Gérard

Publikováno v: Pharmaceutics; Volume 15; Issue 6; Pages: 1694

The dehydration of prednisolone sesquihydrate is studied and characterized by different physico-chemical analysis methods. The meticulous study of this dehydration led to the highlighting of a new solid form (form 3), metastable, never identified bef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::398011afa9bb94cd7c9cf6550677ae66

p-Synephrine enantiomers: binary phase diagram, crystal structure and kinetic stability of a metastable conglomerate monitored by nonlinear optics

Autor: Simon Clevers, Gérard Coquerel, Philippe Espeau, Valérie Dupray, Philippe Négrier, Veronica Ianno

Publikováno v: CrystEngComm
CrystEngComm, Royal Society of Chemistry, 2020, 22 (36), pp.6071-6080. ⟨10.1039/d0ce00841a⟩
CrystEngComm, Royal Society of Chemistry, 2020, 22 (36), pp.6071-6080. ⟨10.1039/D0CE00841A⟩
CrystEngComm, 2020, 22 (36), pp.6071-6080. ⟨10.1039/d0ce00841a⟩

International audience; The crystal structure of (S)-(+)-p-synephrine was refined at 296 K from X-ray powder diffraction. The compound crystallizes in the orthorhombic systemP2(1)2(1)2(1)with four molecules per unit cell and Z ' = 1. The cell paramet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a661f836cd817d447a1de6ba1e906e69
https://doi.org/10.1039/d0ce00841a