Výsledky vyhledávání - "Philippe Emile Fernand Laurent"

Intradermal vaccination with un-adjuvanted sub-unit vaccines triggers skin innate immunity and confers protective respiratory immunity in domestic swine

Autor: Florence Boudet, Bertrand Dubois, Jean-Benoît Le Luduec, Philippe Emile Fernand Laurent, Fabienne Piras, Sabine Debeer, Christine Andreoni, Dominique Kaiserlian

Publikováno v: Vaccine
Vaccine, 2016, 34 (7), pp.914-922. ⟨10.1016/j.vaccine.2015.12.058⟩

International audience; Intradermal (ID) vaccination constitutes a promising approach to induce anti-infectious immunity. This route of immunization has mostly been studied with influenza split-virion vaccines. However, the efficacy of ID vaccination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728d88e5095d998ad2dd4c0950828a69
https://doi.org/10.1016/j.vaccine.2015.12.058

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Echographic measurement of skin thickness in sites suitable for intradermal vaccine injection in infants and children

Autor: Florence Schwarzenbach, Catherine Goujon, Michele Dao Trong, Jean-François Nicolas, Philippe Emile Fernand Laurent, Dominique Ploin, Claude Dubray

Publikováno v: Vaccine. 29:8438-8442

Whereas the knowledge of skin thickness is essential to determine microneedle length and ensure proper administration of and better responses to intradermal vaccines, very few figures are available, especially in infants and children. Using ultrasoun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b85316034c2086b71c48d4a17651181
https://doi.org/10.1016/j.vaccine.2011.07.111

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Evaluation of the clinical performance of a new intradermal vaccine administration technique and associated delivery system

Autor: Stephane Bonnet, John A. Mikszta, Philippe Emile Fernand Laurent, Paul G. Alchas, Noel G. Harvey, Ronald J. Pettis, Paulina Regolini

Publikováno v: Vaccine. 25:8833-8842

The advantages of intradermal (ID) vaccine administration have been well documented but difficulties in performing ID vaccination using existing techniques and equipment have limited it's clinical application. In the present study, a new ID injection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369c8cd76c4f1666785e719b16ad0f11
https://doi.org/10.1016/j.vaccine.2007.10.020

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Nine μg intradermal influenza vaccine and 15 μg intramuscular influenza vaccine induce similar cellular and humoral immune responses in adults

Autor: Nolwenn Nougarede, Béatrice Vanbervliet, Florence Boudet, Philippe Emile Fernand Laurent, K. Rodet, Catherine Goujon, Ana Hennino, Jean-François Nicolas, Hélène Bisceglia, Aurore Rozières

Publikováno v: Human Vaccines & Immunotherapeutics

Intanza® 9 μg (Sanofi Pasteur), a trivalent split-virion vaccine administered by intradermal (ID) injection, was approved in Europe in 2009 for the prevention of seasonal influenza in adults 18 to 59 years. Here, we examined the immune responses in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fae24ec56a9b083f3f628caca8ff814
https://pubmed.ncbi.nlm.nih.gov/25483667

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Comparative histology and immunohistochemistry of porcine versus human skin

Autor: Dominique Kaiserlian, Bertrand Dubois, Jean-Benoît Le Luduec, Jean Kanitakis, Jean-François Nicolas, Sabine Debeer, Philippe Emile Fernand Laurent

Publikováno v: European journal of dermatology : EJD. 23(4)

Background. Porcine skin is increasingly being employed as a model of human skin in various research fields, including pharmacology, toxicology and immunology, with particular interest in percutaneous permeation and organ transplantation. Porcine ski

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75d8783629bd25f0a11e5099f64239d
https://pubmed.ncbi.nlm.nih.gov/24047577

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Evaluation of performance, safety, subject acceptance, and compliance of a disposable autoinjector for subcutaneous injections in healthy volunteers

Autor: Herve Abry, Philippe Emile Fernand Laurent, Celine Feger, Yves Donazzolo, Mathilde Latreille, Florence Schwarzenbach, Joël Cotten, Cecile Berteau, Julie Berube

Publikováno v: Patient preference and adherence

Cecile Berteau1, Florence Schwarzenbach1, Yves Donazzolo2, Mathilde Latreille2, Julie Berube3, Herve Abry1, Joël Cotten1, Celine Feger1, Philippe E Laurent11BD Medical Pharmaceutical Systems, Le-Pont-de-Claix, 2Eurofins Optimed Clinical Research, Gi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9e80e58301a6f76d5d1d20664437aa
https://www.dovepress.com/evaluation-of-performance-safety-subject-acceptance-and-compliance-of--peer-reviewed-article-PPA

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Safety and efficacy of novel dermal and epidermal microneedle delivery systems for rabies vaccination in healthy adults

Autor: Marc Fantino, John A. Mikszta, Hervé Bourhy, Paul G. Alchas, Philippe Emile Fernand Laurent

Publikováno v: Vaccine
Vaccine, Elsevier, 2010, 28 (36), pp.5850-6. ⟨10.1016/j.vaccine.2010.06.062⟩
Vaccine, 2010, 28 (36), pp.5850-6. ⟨10.1016/j.vaccine.2010.06.062⟩

International audience; In the present pilot study, intradermal ID delivery systems with a BD microneedle from 1 to 3mm in length, and epidermal delivery (BD skin abrader) through abraded skin surface relative to standard intramuscular injection were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d903a7d3efce4ae8d2f9cd462cbc4e8b
https://hal-pasteur.archives-ouvertes.fr/pasteur-01491942

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Immunogenicity and safety of intradermal influenza vaccination in renal transplant patients who were non-responders to conventional influenza vaccination

Autor: Philippe Emile Fernand Laurent, Sameh Daoud, Jean-François Nicolas, Catherine Goujon-Henry, Emmanuel Morelon, Françoise Weber, Claire Pouteil Noble, Remi Cahen, Dominique Kaiserlian

Publikováno v: Vaccine. 28(42)

Seasonal influenza epidemics are associated with high morbidity and mortality particularly in high-risk patients. Conventionally administered influenza vaccines show reduced efficacy in populations with weakened immune systems such as solid-organ tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0ff813a4e210f04183927e04f00d1b
https://pubmed.ncbi.nlm.nih.gov/20709000

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Cutaneous delivery of prophylactic and therapeutic vaccines: historical perspective and future outlook

Autor: John A. Mikszta, Philippe Emile Fernand Laurent

Publikováno v: Expert review of vaccines. 7(9)

The skin has long been recognized as an attractive target for vaccine administration. A number of clinical studies have tested the epidermal and dermal routes of delivery using a variety of vaccines over the years. In many cases, cutaneous administra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c92c56245e8146307447fe3c16894d
https://pubmed.ncbi.nlm.nih.gov/18980537

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A novel needle for subcutaneous injection of interferon beta-1a: effect on pain in volunteers and satisfaction in patients with multiple sclerosis

Autor: Lionel Vedrine, Amer Jaber, Wes A Prais, Philippe Emile Fernand Laurent, Julie Berube, Gian Battista Bozzato

Publikováno v: BMC Neurology, Vol 8, Iss 1, p 38 (2008)
BMC Neurology

Background To reduce injection pain and improve satisfaction, a thinner (29-gauge [29G]), sharper (5-bevel) needle than the 27G/3-bevel needle used previously to inject interferon (IFN) beta-1a, 44 or 22 mcg subcutaneously (sc) three times weekly (ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0d1f5549e5be9af321c54d7ba33f95
https://doi.org/10.1186/1471-2377-8-38

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