Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Philippe Duret"'
Autor:
Philippe Duret
Mobilisé en 1914, le soldat Edmond Duret écrit des lettres jusqu'à sa démobilisation en 1919. La guerre a construit et changé ce jeune homme ; confronté pendant ces années à la technique et la modernité, il s'oriente vers des études d'ingé
Autor:
Philippe Duret, Alain Fournet, Mohamed A. Fakhfakh, Reynald Hocquemiller, Xavier Franck, Christine Herrenknecht, Bruno Figadère
Publikováno v:
Journal of Chromatography A. 1011:55-65
Centrifugal partition chromatography has been successfully applied to the separation of 2-alkylquinolines from liquid combinatorial synthesis crude samples. Original gradient elution using the ternary two-phase solvent systems heptane–water–aceto
Publikováno v:
Natural Product Letters. 14:239-245
A new Annonaceous acetogenin, robustocin, was isolated from the seeds of Annona muricata (Annonaceae). Its structure was deduced by NMR and mass spectrometric methods. Absolute configurations were determined by the Mosher's ester methodology. This co
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:1821-1826
Semisynthetic derivatives were prepared from two natural annonaceous acetogenins, rolliniastatin-1 and squamocin, and their cytotoxicity was evaluated. Amino derivatives show decreased bioactivity. Isorolliniastatin-1 was found to be much less toxic
Publikováno v:
The Journal of Organic Chemistry. 63:4717-4720
Structural elucidation of absolute configurations of the stereogenic centers of acetogenins of Annonaceae was performed using the modified Mosher's method. Thus, by replacing MTPA (methoxytrifluoromethylphenylacetic acid) by 2-NMA (naphthylmethoxyace
Publikováno v:
Phytochemistry. 48:499-506
Two new C 37 tetrahydroxy adjacent bis-tetrahydrofuran acetogenins with a vicinal diol, bulladecin and atemotetrolin, were isolated from the methanol extract of Annona atemoya seeds and characterized by spectroscopic techniques. In addition the known
Publikováno v:
Journal of Natural Products. 61:576-579
Phytochemical investigation of roots of Annona muricata led to the identification of seven mono-tetrahydrofuran (mono-THF) acetogenins. Six new acetogenins having the unusual cis-configuration of the THF ring, cis-solamin (1), cis-panatellin (2), cis
Publikováno v:
Tetrahedron Letters. 38:8849-8852
in basic conditions, non-4-hydroxylated annonaeous acetogenins may be epimerized by light basic treatment. The two epimers are inseparable by HPLC, have identical spectroscopic data (MS, IR, UV, 1 H and 13 C NMR). However, specific rotation of the ep
Publikováno v:
Phytochemistry. 45:1423-1426
A new C 35 tetrahydroxy adjacent bis-tetrahydrofuran acetogenin, annonisin, has been isolated from the methanol extract of Annona atemoya seeds and characterized by spectroscopic techniques, in addition to the known compounds, molvizarin, parviflorin
Autor:
M. Peres, C. Pierard, Reynald Hocquemiller, Philippe Duret, A.-I. Waechter, Bruno Figadère, André Cavé
Publikováno v:
Tetrahedron Letters. 37:7043-7046
The absolute configuration of the C-36 or C-34 chiral centers of Annonaceous acetogenins has been determined by simple enzymatic method focusing on the HPLC detection of NADH issued from the enzymatic oxidation of L- or D-lactic acid (obtained by oxi