Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Philippe Dupraz"'
Autor:
Zoltan Mathe, Philippe Dupraz, Chris Rinsch, Bernard Thorens, Domenico Bosco, Marie Zbinden, Philippe Morel, Thierry Berney, Michael S. Pepper
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Early revascularization of pancreatic islet cells after transplantation is crucial for engraftment, and it has been suggested that vascular endothelial growth factor-A (VEGF-A) plays a significant role in this process. Although VEGF gene therapy can
Externí odkaz:
https://doaj.org/article/4b13d8aaaed54354a8442dc43bbf4faf
Autor:
Antu K. Dey, Angela Lim, Jessica P. Dawson, Adin Ross-Gillespie, Mara Rossi, Mirva Hejjaoui Simoneau, Cyril Boucher, Wolf Palinsky, Mark B. Feinberg, Joseph G. Jardine, Bernhard Valldorf, Hervé Broly, Dennis R. Burton, Thomas Hassell, Philippe Dupraz, Rita Agostinetto, Devin Sok
Publikováno v:
Biotechnology and Bioengineering
Therapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally‐derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51009b838b0fa98ca7b9d372a4dbd04a
https://pubmed.ncbi.nlm.nih.gov/34796474
https://pubmed.ncbi.nlm.nih.gov/34796474
Autor:
Rita Agostinetto, Jessica Dawson, Angela Lim, Mirva Hejjaoui-simoneau, Cyril Boucher, Bernhard Valldorf, Adin Ross-gillespie, Joseph Jardine, Devin Sok, Dennis Burton, Thomas Hassell, Hervé Broly, Wolf Palinsky, Philippe Dupraz, Mark Feinberg, Antu Dey
Therapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally-derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66208bd81826345146315939eff017c4
https://doi.org/10.22541/au.163251349.96835693/v1
https://doi.org/10.22541/au.163251349.96835693/v1
Autor:
Philippe Dupraz, Bruno Antonsson, Jean-Philippe Gaudry, Christophe Sauvage, Stephane Busso, Christian Arod, Renata Pankiewicz
Publikováno v:
Protein Expression and Purification. 58:94-102
Adhesion molecules are essential for a wide range of biological and physiological functions, including cell-cell interactions, cell interactions with the extracellular matrix, cell migration, proliferation and survival. Defects in cell adhesion have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3e77d9f250085fd7e291724c54ef8d
https://doi.org/10.1016/j.pep.2007.10.025
https://doi.org/10.1016/j.pep.2007.10.025
Autor:
Thierry Berney, Z Mathe, Domenico Bosco, Michael S. Pepper, Chris Rinsch, Philippe Dupraz, Philippe Morel, Marie Zbinden, Bernard Thorens
Publikováno v:
Cell Transplantation, Vol. 15, No 7 (2006) pp. 621-36
Cell Transplantation, Vol 15 (2006)
Cell Transplantation, Vol 15 (2006)
Early revascularization of pancreatic islet cells after transplantation is crucial for engraftment, and it has been suggested that vascular endothelial growth factor-A (VEGF-A) plays a significant role in this process. Although VEGF gene therapy can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c030c52cbd95a0f2704fab06c2a1dd
https://doi.org/10.3727/000000006783981675
https://doi.org/10.3727/000000006783981675
Publikováno v:
Annals of the New York Academy of Sciences. 944:267-270
In this paper we explore the possibility of improving, by genetic engineering, the resistance of insulin-secreting cells to the metabolic and inflammatory stresses that are anticipated to limit their function and survival when encapsulated and transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c673dc2f826ffed1c1769867db6a381e
https://doi.org/10.1111/j.1749-6632.2001.tb03838.x
https://doi.org/10.1111/j.1749-6632.2001.tb03838.x
Publikováno v:
Journal of Cellular Biochemistry, Vol. 98, No 2 (2006) pp. 267-86
Primary cultures of bovine microvascular endothelial cells (BME) isolated from the adrenal cortex, are commonly used to study vascular endothelium, but have a limited life span. To circumvent these limitations, we have immortalized BME cells with eit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1e5c36312f86e085aba7677de6ce73
https://doi.org/10.1002/jcb.20715
https://doi.org/10.1002/jcb.20715
Autor:
N.A. Andersen, Philippe Dupraz, Thomas Mandrup-Poulsen, N. Sandhu, Allan E. Karlsen, Anne Oberson, Bernard Thorens, M.A. Nikulina, Z. Shamim, Christophe Bonny
Publikováno v:
Cytokine. 24:13-24
The stress-activated protein kinase c-Jun NH2-terminal kinase (JNK) is a central signal for interleukin-1beta (IL-1beta)-induced apoptosis in insulin-producing beta-cells. The cell-permeable peptide inhibitor of JNK (JNKI1), that introduces the JNK b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9eeb0171b9782b25a4f1659bca0783
https://doi.org/10.1016/s1043-4666(03)00242-4
https://doi.org/10.1016/s1043-4666(03)00242-4
Autor:
Philippe Dupraz, Gerhard Christofori, Bernard Thorens, Paolo Fiorina, Alberto M. Davalli, Francesca Galbiati, Ugo Cavallaro, Luca Polastri
Publikováno v:
Endocrinology. 144:1832-1841
We have previously reported that in tumorigenic pancreatic beta-cells, calcitriol exerts a potent antitumorigenic effect by inducing apoptosis, cell growth inhibition, and reduction of solid beta-cell tumors. Here we have studied the molecular pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68355134725fab342228dc78a215955
https://doi.org/10.1210/en.2002-221014
https://doi.org/10.1210/en.2002-221014
Autor:
Christian Boitard, Philippe Dupraz, Bernard Thorens, D. Rottembourg, Sandra Cottet, Isabelle Tardivel, Jean-Claude Carel, P. Cattan
Publikováno v:
Diabetologia. 46:504-510
betaTC-tet (H2(k)) is a conditional insulinoma cell line derived from transgenic mice expressing a tetracycline-regulated oncogene. Transgenic expression of several proteins implicated in the apoptotic pathways increase the resistance of betaTC-tet c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06572f86415b69a30876b3dfb6a1f91
https://doi.org/10.1007/s00125-003-1062-3
https://doi.org/10.1007/s00125-003-1062-3