Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Philippe Donatien"'
Autor:
Gordon Sloan, Philippe Donatien, Rosario Privitera, Pallai Shillo, Sharon Caunt, Dinesh Selvarajah, Praveen Anand, Solomon Tesfaye
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
BackgroundIdentifying distinct mechanisms and biomarkers for painful diabetic peripheral neuropathy (DPN) is required for advancing the treatment of this major global unmet clinical need. We previously provided evidence in calf skin biopsies that dis
Externí odkaz:
https://doaj.org/article/cdd9e02ff619458699301c72fbbce9e1
Autor:
Praveen Anand, Rosario Privitera, Philippe Donatien, Hassan Fadavi, Solomon Tesfaye, Vassiliki Bravis, V. Peter Misra
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionCurrent oral treatments for pain in diabetic peripheral neuropathy (DPN) do not affect the progression of DPN i.e., “disease modification.” We assessed whether Capsaicin 8% patch treatment can provide pain relief and also restore nerv
Externí odkaz:
https://doaj.org/article/de942a7d156443aa88b9dc6998ec0439
Autor:
Pallai Shillo, Yiangos Yiangou, Philippe Donatien, Marni Greig, Dinesh Selvarajah, Iain D. Wilkinson, Praveen Anand, Solomon Tesfaye
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Painful diabetic peripheral neuropathy can be intractable with a major impact, yet the underlying pain mechanisms remain uncertain. A range of neuronal and vascular biomarkers was investigated in painful diabetic peripheral neuropathy (painful-DPN) a
Externí odkaz:
https://doaj.org/article/9cd47bec165d41d88d07d8724f042f33
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Introduction: Neuropathic pain associated with Non-freezing Cold Injury (NFCI) is a major burden to military service personnel. A key feature of NFCI is reduction of the intra-epidermal nerve fibre density in skin biopsies, in keeping with painful ne
Externí odkaz:
https://doaj.org/article/347cef428b3141a0856faa62ffca191f
Autor:
Philippe Donatien, Uma Anand, Yiangos Yiangou, Marco Sinisi, Michael Fox, Anthony MacQuillan, Tom Quick, Yuri E. Korchev, Praveen Anand
Publikováno v:
PAIN Reports, Vol 3, Iss 5, p e676 (2018)
Abstract. Introduction:. Granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) is highly expressed in peripheral macrophages and microglia, and is involved in arthritis and cancer pain in animal models. However, there is limited informa
Externí odkaz:
https://doaj.org/article/114efff2bd784ba58c890bfb96b25f5b
Autor:
Praveen Anand, Rosario Privitera, Yiangos Yiangou, Philippe Donatien, Rolfe Birch, Peter Misra
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
BackgroundTrench foot, or non-freezing cold injury (NFCI), results from cold exposure of sufficient severity and duration above freezing point, with consequent sensory and vascular abnormalities which may persist for years. Based on observations of T
Externí odkaz:
https://doaj.org/article/505dcdbceb06474fb50fed410a9b6bc1
Autor:
Kalnisha Naidoo, Enas Elsafa, Harpreet Wasan, Peter Misra, Praveen Anand, Philippe Donatien, Yiangos Yiangou, Amin Rahemtulla, Laura M. Kenny, Rosario Privitera, Hani Gabra
Publikováno v:
Journal of Pain Research. 12:2039-2052
Purpose Chemotherapy-induced peripheral neuropathy (CIPN) with associated chronic pain is a common and disabling condition. Current treatments for neuropathic pain in CIPN are largely ineffective, with unfavorable side-effects. The capsaicin 8% patch
Autor:
Praveen, Anand, Enas, Elsafa, Rosario, Privitera, Kalnisha, Naidoo, Yiangos, Yiangou, Philippe, Donatien, Hani, Gabra, Harpreet, Wasan, Laura, Kenny, Amin, Rahemtulla, Peter, Misra
Publikováno v:
Journal of Pain Research
Purpose Chemotherapy-induced peripheral neuropathy (CIPN) with associated chronic pain is a common and disabling condition. Current treatments for neuropathic pain in CIPN are largely ineffective, with unfavorable side-effects. The capsaicin 8% patch
Autor:
Ann Sandison, Francesco Carlucci, Guang Sheng Ling, Marina Botto, Attia Ishaque, Marta Szajna, Philippe Donatien, H. Terence Cook
Publikováno v:
The Journal of Immunology. 196:1488-1494
The complement component C1q is known to play a controversial role in the pathogenesis of systemic lupus erythematosus, but the underlying mechanisms remain poorly understood. Intraperitoneal injection of pristane induces a lupus-like syndrome whose
Autor:
Pallai Shillo, Dinesh Selvarajah, Philippe Donatien, IA Wilkinson, Praveen Anand, Yiangos Yiangou, Marni Greig, Solomon Tesfaye
Publikováno v:
Diabetic Medicine. 34:31-33