Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Philippe Dehio"'
Autor:
Jonas, Lötscher, Adrià-Arnau, Martí I Líndez, Nicole, Kirchhammer, Elisabetta, Cribioli, Greta Maria Paola, Giordano Attianese, Marcel P, Trefny, Markus, Lenz, Sacha I, Rothschild, Paolo, Strati, Marco, Künzli, Claudia, Lotter, Susanne H, Schenk, Philippe, Dehio, Jordan, Löliger, Ludivine, Litzler, David, Schreiner, Victoria, Koch, Nicolas, Page, Dahye, Lee, Jasmin, Grählert, Dmitry, Kuzmin, Anne-Valérie, Burgener, Doron, Merkler, Miklos, Pless, Maria L, Balmer, Walter, Reith, Jörg, Huwyler, Melita, Irving, Carolyn G, King, Alfred, Zippelius, Christoph, Hess
Publikováno v:
Cell. 185(4)
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6cfb6d8cca3f0ddb2bc7221e4f0bfe8
https://pubmed.ncbi.nlm.nih.gov/35260350
https://pubmed.ncbi.nlm.nih.gov/35260350
Autor:
Jonas Lötscher, Adrià-Arnau Martí i Líndez, Nicole Kirchhammer, Elisabetta Cribioli, Greta Maria Paola Giordano Attianese, Marcel P. Trefny, Markus Lenz, Sacha I. Rothschild, Paolo Strati, Marco Künzli, Claudia Lotter, Susanne H. Schenk, Philippe Dehio, Jordan Löliger, Ludivine Litzler, David Schreiner, Victoria Koch, Nicolas Page, Dahye Lee, Jasmin Grählert, Dmitry Kuzmin, Anne-Valérie Burgener, Doron Merkler, Miklos Pless, Maria L. Balmer, Walter Reith, Jörg Huwyler, Melita Irving, Carolyn G. King, Alfred Zippelius, Christoph Hess
Publikováno v:
Cell. 185:585-602.e29
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8+ T��cells, thereby augmenting calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aac832ab7bc74750040c9812d41abd
https://doi.org/10.1016/j.cell.2021.12.039
https://doi.org/10.1016/j.cell.2021.12.039
Autor:
Thorsten R. Mempel, Philippe Dehio, Andrew D. Luster, Aleksandra J. Ozga, Rachel L. Servis, Mateus E. Lopes, Mauro Di Pilato, Jeffrey Lian, Melvyn T. Chow
Publikováno v:
Immunity
CD8(+) T cells responding to chronic infection adapt an altered differentiation program that provides some restrain on pathogen replication yet limits immunopathology. This adaptation is imprinted in stem-like cells and propagated to their progeny. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d02c2e33bf5ef4aaf9cb53352f38ebe
https://doi.org/10.1016/j.immuni.2021.11.002
https://doi.org/10.1016/j.immuni.2021.11.002
Autor:
Maria L, Balmer, Eric H, Ma, Andrew J, Thompson, Raja, Epple, Gunhild, Unterstab, Jonas, Lötscher, Philippe, Dehio, Christian M, Schürch, Jan D, Warncke, Gaëlle, Perrin, Anne-Kathrin, Woischnig, Jasmin, Grählert, Jordan, Löliger, Nadine, Assmann, Glenn R, Bantug, Olivier P, Schären, Nina, Khanna, Adrian, Egli, Lukas, Bubendorf, Katharina, Rentsch, Siegfried, Hapfelmeier, Russell G, Jones, Christoph, Hess
Publikováno v:
Cell metabolism. 32(3)
Serum acetate increases upon systemic infection. Acutely, assimilation of acetate expands the capacity of memory CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ced85c387034c37bec0dfbde22f9071
https://pubmed.ncbi.nlm.nih.gov/32877687
https://pubmed.ncbi.nlm.nih.gov/32877687
Autor:
Lukas Matthaeus Altenburger, Yosuke Harada, Philippe Dehio, Nora Ruef, Matthias Mehling, Jens Volker Stein
Publikováno v:
The Journal of Immunology. 206:98.29-98.29
Naïve T cells and dendritic cells (DCs) are drawn to lymphoid tissue by the chemokine receptor CCR7, where its ligands CCL19 and CCL21 are secreted by lymphoid stroma. There, CCR7 fuels the fast migration of naïve T cells to expedite encounters wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::051e47cc468d4a874382b61511a68ddf
https://doi.org/10.4049/jimmunol.206.supp.98.29
https://doi.org/10.4049/jimmunol.206.supp.98.29
Autor:
Leyla Develioglu, Annaïse Jauch, Weldy V. Bonilla, Timo Glatter, Siegfried Hapfelmeier, Glenn R. Bantug, Andrew J. Macpherson, Anne-Valérie Burgener, Magdalena A. Krzyzaniak, Russell G. Jones, Sarah Dimeloe, Emma Slack, Simona P. Pfister, Eric H. Ma, Mike Recher, Jasmin Grählert, Philippe Dehio, Christoph Hess, Marco Fischer, Réka Belle, Carolyn G. King, Maria L. Balmer
Publikováno v:
Immunity
IMMUNITY
IMMUNITY
How systemic metabolic alterations during acute infections impact immune cell function remains poorly understood. We found that acetate accumulates in the serum within hours of systemic bacterial infections and that these increased acetate concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62971b56e64825065fb61317529c2a2e
https://doi.org/10.1016/j.immuni.2016.03.016
https://doi.org/10.1016/j.immuni.2016.03.016
Autor:
Jordan Löliger, Jonas Lötscher, Russell G. Jones, Anne-Kathrin Woischnig, Maria L. Balmer, Nina Khanna, Lukas Bubendorf, Adrian Egli, Nadine Assmann, Eric H. Ma, Jasmin Grählert, Jan D. Warncke, Olivier P. Schären, Andrew J. Thompson, Raja Epple, Katharina Rentsch, Gaëlle Perrin, Christian M. Schürch, Glenn R. Bantug, Gunhild Unterstab, Siegfried Hapfelmeier, Philippe Dehio, Christoph Hess
Publikováno v:
Cell Metabolism. 32:457-467.e5
Serum acetate increases upon systemic infection. Acutely, assimilation of acetate expands the capacity of memory CD8+ T cells to produce IFN-γ. Whether acetate modulates memory CD8+ T cell metabolism and function during pathogen re-encounter remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22717b154516a8fe1b556ae3733778bb
https://doi.org/10.1016/j.cmet.2020.07.004
https://doi.org/10.1016/j.cmet.2020.07.004