How important is thermodynamics for identifying elementary flux modes?

Autor: Sabine Peres, Mario Jolicœur, Cécile Moulin, Philippe Dague, Stefan Schuster

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171440 (2017)

We present a method for computing thermodynamically feasible elementary flux modes (tEFMs) using equilibrium constants without need of internal metabolite concentrations. The method is compared with the method based on a binary distinction between re

Externí odkaz: https://doaj.org/article/2cf2cd42618b475cbc90c4cc76e42a08

Could the poor ability of psychological theories to explain inter-individual variability be a consequence of the tacit assumption of structural homogeneity?

Autor: Marc Irigoin-Guichandut, MULLER Laurent, Loïc Paulevé, Philippe Dague

Psychological theories and data models face the challenge of their poor ability to explain inter-individual variability. This issue has already been addressed targeting data models and asking: Is there data models which may be used to connect intra-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8975a06a97da092eb2850c86e22dd3c9
https://doi.org/10.31234/osf.io/h9c7d

A Coloured Petri Nets Based Attack Tolerance Framework

Autor: Lina Ye, Philippe Dague, Lei Liu, Fatiha Zaïdi, Wenbo Zhou

Publikováno v: APSEC
the 27th Asia-Pacific Software Engineering Conference
27th Asia-Pacific Software Engineering Conference (APSEC 2020)
27th Asia-Pacific Software Engineering Conference (APSEC 2020), IEEE, Dec 2020, Singapore, Singapore
the 27th Asia-Pacific Software Engineering Conference, In press

International audience; Web services provide a general basis of convenient access and operation for cloud applications. However, such services become very vulnerable when being attacked, especially in the situation where service continuity is one of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6aec855ef89d9719eb601bbfd7b4d1
https://doi.org/10.1109/apsec51365.2020.00024

Thermodynamic constraints for identifying elementary flux modes

Autor: Philippe Dague, Stefan Schuster, Sabine Peres

Publikováno v: Biochemical Society Transactions
Biochemical Society Transactions, Portland Press, 2018, 46 (3), pp.641-647. ⟨10.1042/BST20170260⟩

International audience; Metabolic pathway analysis is a key method to study metabolism and the elementary flux modes (EFMs) is one major concept allowing one to analyze the network in terms of minimal pathways. Their practical use has been hampered b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ef2b885fc3d1969556d87cabafc993
https://pubmed.ncbi.nlm.nih.gov/29743275

Abstractions refinement for hybrid systems diagnosability analysis

Autor: Lina Ye, Hadi Zaatiti, Louise Travé-Massuyès, Jean-Pierre Gallois, Philippe Dague

Publikováno v: Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems
Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems, Springer, 2018, 〈10.1007/978-3-319-74962-4_11〉
Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems, Springer, 2018, ⟨10.1007/978-3-319-74962-4_11⟩
Diagnosability, Security and Safety of Hybrid Dynamic and Cyber-Physical Systems ISBN: 9783319749617

Hybrid systems are complex systems that combine both discrete and continuous behaviors. Verifying behavioral or safety properties of such systems, either at design stage such as state reachability, diagnosability, and predictability or on-line such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e84aadc1a3515033ed3996945745b0
https://hal.archives-ouvertes.fr/hal-01676931