Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Philippe Ciofi"'
Autor:
Laura Kuczynski-Noyau, Sixtine Karmann, Paolo Alberton, Ines Martinez-Corral, Sreekala Nampoothiri, Florent Sauvé, Tori Lhomme, Carmelo Quarta, Suneel S. Apte, Sébastien Bouret, Attila Aszodi, Sowmyalakshmi Rasika, Philippe Ciofi, Julie Dam, Vincent Prévot, Virginie Mattot
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The hypothalamic arcuate nucleus (ARH) contains neurons vital for maintaining energy homeostasis that sense and respond to changes in blood-borne metabolic hormones. Despite its juxtaposition to the median eminence (ME), a circumventricular
Externí odkaz:
https://doaj.org/article/e94870fe89f04d25bdc4bbe95aec86d1
Autor:
Qiang Yu, Igor Gamayun, Philipp Wartenberg, Qian Zhang, Sen Qiao, Soumya Kusumakshi, Sarah Candlish, Viktoria Götz, Shuping Wen, Debajyoti Das, Amanda Wyatt, Vanessa Wahl, Fabien Ectors, Kathrin Kattler, Daniela Yildiz, Vincent Prevot, Markus Schwaninger, Gaetan Ternier, Paolo Giacobini, Philippe Ciofi, Timo D. Müller, Ulrich Boehm
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The median eminence (ME) at the base of the brain controls body homeostasis. Here, the authors describe a functional tanycyte subpopulation at the ME which tastes the surrounding milieu, responds to metabolic signals and regulates glucose homeostasis
Externí odkaz:
https://doaj.org/article/4b5c1f7cda5c41f68832e3a28a512ae0
Autor:
Julien Bourel, Vincent Planche, Nadège Dubourdieu, Aymeric Oliveira, Alexandra Séré, Eva-Gunnel Ducourneau, Marion Tible, Marlène Maitre, Thierry Lesté-Lasserre, Agnes Nadjar, Aline Desmedt, Philippe Ciofi, Stéphane H. Oliet, Aude Panatier, Thomas Tourdias
Publikováno v:
Neurobiology of Disease, Vol 160, Iss , Pp 105533- (2021)
Memory impairment is one of the disabling manifestations of multiple sclerosis (MS) possibly present from the early stages of the disease and for which there is no specific treatment. Hippocampal synaptic dysfunction and dendritic loss, associated wi
Externí odkaz:
https://doaj.org/article/2795f1f4556d468198d33235f37e06f4
Autor:
Antonio C. Pagano Zottola, Ilenia Severi, Astrid Cannich, Philippe Ciofi, Daniela Cota, Giovanni Marsicano, Antonio Giordano, Luigi Bellocchio
Publikováno v:
Cells, Vol 11, Iss 16, p 2582 (2022)
Via activation of the cannabinoid type-1 (CB1) receptor, endogenous and exogenous cannabinoids modulate important biochemical and cellular processes in adipocytes. Several pieces of evidence suggest that alterations of mitochondrial physiology might
Externí odkaz:
https://doaj.org/article/b1a7ee35653744e2a7a1bdec83bff3d0
Autor:
Éva Rumpler, Szabolcs Takács, Balázs Göcz, Ferenc Baska, Ottó Szenci, András Horváth, Philippe Ciofi, Erik Hrabovszky, Katalin Skrapits
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neurons co-synthesizing kisspeptin (KP), neurokinin B (NKB), and dynorphin (“KNDy neurons”) in the hypothalamic arcuate/infundibular nucleus (INF) form a crucial component of the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) “p
Externí odkaz:
https://doaj.org/article/d17a883a7d7a49539a0b942cd2f30420
Autor:
Paolo Giacobini, Jyoti Parkash, Céline Campagne, Andrea Messina, Filippo Casoni, Charlotte Vanacker, Fanny Langlet, Barbara Hobo, Gabriella Cagnoni, Sarah Gallet, Naresh Kumar Hanchate, Danièle Mazur, Masahiko Taniguchi, Massimiliano Mazzone, Joost Verhaagen, Philippe Ciofi, Sébastien G Bouret, Luca Tamagnone, Vincent Prevot
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001808 (2014)
Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothe
Externí odkaz:
https://doaj.org/article/e03a0204fd6c4ff899ff4801bc03f5d9
Autor:
Katalin Skrapits, Beáta Á Borsay, László Herczeg, Philippe Ciofi, Stephen R Bloom, Mohammad A Ghatei, Waljit S Dhillo, Zsolt Liposits, Erik Hrabovszky
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103977 (2014)
Kisspeptin (KP)- and neurokinin B (NKB)- synthesizing neurons of the hypothalamic arcuate nucleus play a pivotal role in the regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion. Unlike in rodents and sheep, the homologous KP and N
Externí odkaz:
https://doaj.org/article/86fff0829ce74c7ca53bd69640d490cf
Autor:
Erik Hrabovszky, Beáta Á Borsay, Kálmán Rácz, László Herczeg, Philippe Ciofi, Stephen R Bloom, Mohammad A Ghatei, Waljit S Dhillo, Zsolt Liposits
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72369 (2013)
Neurons synthesizing neurokinin B (NKB) and kisspeptin (KP) in the hypothalamic arcuate nucleus represent important upstream regulators of pulsatile gonadotropin-releasing hormone (GnRH) neurosecretion. In search of neuropeptides co-expressed in anal
Externí odkaz:
https://doaj.org/article/473b5db447464acb8b82dad3555863f7
Autor:
Juergen Siepmann, Delphine Franssen, François P. Pralong, Tori Lhomme, Cecile Allet, Anne-Simone Parent, Adrian Coutteau-Robles, Manuel Tena-Sempere, Gabriel Corfas, Danièle Mazur, S. Rasika, Sarah Geller, Anne Loyens, Maria Manfredi-Lozano, Ariane Sharif, Giuliana Pellegrino, Virginia Delli, Vincent Prevot, Marion Martin, Sergio R. Ojeda, Philippe Ciofi, Virginie Mansuy
Publikováno v:
Nature Neuroscience. 24:1660-1672
Neurons that produce gonadotropin-releasing hormone (GnRH), which control fertility, complete their nose-to-brain migration by birth. However, their function depends on integration within a complex neuroglial network during postnatal development. Her
Autor:
Konstantina Chachlaki, Andrea Messina, Virginia Delli, Valerie Leysen, Csilla Maurnyi, Chieko Huber, Gaëtan Ternier, Katalin Skrapits, Georgios Papadakis, Sonal Shruti, Maria Kapanidou, Xu Cheng, James Acierno, Jesse Rademaker, Sowmyalakshmi Rasika, Richard Quinton, Marek Niedziela, Dagmar L’Allemand, Duarte Pignatelli, Mirjam Dirlewander, Mariarosaria Lang-Muritano, Patrick Kempf, Sophie Catteau-Jonard, Nicolas J. Niederländer, Philippe Ciofi, Manuel Tena-Sempere, John Garthwaite, Laurent Storme, Paul Avan, Erik Hrabovszky, Alan Carleton, Federico Santoni, Paolo Giacobini, Nelly Pitteloud, Vincent Prevot
Publikováno v:
Science Translational Medicine
Science Translational Medicine, 2022, 14 (665), pp.eabh2369. ⟨10.1126/scitranslmed.abh2369⟩
Science translational medicine, vol. 14, no. 665, pp. eabh2369
Science Translational Medicine, 2022, 14 (665), pp.eabh2369. ⟨10.1126/scitranslmed.abh2369⟩
Science translational medicine, vol. 14, no. 665, pp. eabh2369
The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for reproduction. We hypothesized that a disruption of neuronal NO synthase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b9ba2a2f53ed6983bfc3208da7475d
https://www.hal.inserm.fr/inserm-03841246
https://www.hal.inserm.fr/inserm-03841246