Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Philippe Brunet De la Grange"'
Autor:
Marija Vlaski-Lafarge, Veronique Labat, Alexandra Brandy, Alice Refeyton, Pascale Duchez, Laura Rodriguez, Nyere Gibson, Philippe Brunet de la Grange, Zoran Ivanovic
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
It is known that cancer stem cells (CSCs) with the largest proliferative capacity survive the anoxic and/or ischemic conditions present inside tumorous tissue. In this study we test whether normal stem cells can survive under the same conditions due
Externí odkaz:
https://doaj.org/article/f651b76c7a114986917cb75371690dd8
Autor:
Véronique Labat, Eva Nguyen van Thanh dit Bayard, Alice Refeyton, Mathilde Huart, Maryse Avalon, Christelle Debeissat, Laura Rodriguez, Philippe Brunet de la Grange, Zoran Ivanovic, Marija Vlaski-Lafarge
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 540 (2022)
Physiological low oxygen (O2) concentration (2 concentration, via the stabilization of hypoxia-induced transcription factors (HIFs), intervenes with Notch signaling in the control of cell fate. In addition, Notch activation is implicated in the regul
Externí odkaz:
https://doaj.org/article/c9ec872aa2fc44619424e9fe40f0b2f9
Autor:
Christelle Debeissat, Maryse Avalon, Mathilde Huart, Pascale Duchez, Laura Rodriguez, Marija Vlaski-Lafarge, Zoran Ivanovic, Philippe Brunet de la Grange
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 431 (2022)
Steady state peripheral blood (SSPB) contains hematopoietic stem and progenitor cells (HSPCs) presenting characteristics of real hematopoietic stem cells, and thus represents an interesting alternative cell supply for hematopoietic cell transplantati
Externí odkaz:
https://doaj.org/article/8b04259c5b5640d39e06da821c5c3372
Autor:
Pierre-Yves Dumas, Olivier Mansier, Valerie Prouzet-Mauleon, Junji Koya, Arnaud Villacreces, Philippe Brunet de la Grange, Damien Luque Paz, Audrey Bidet, Jean-Max Pasquet, Vincent Praloran, Franck Salin, Mineo Kurokawa, François-Xavier Mahon, Bruno Cardinaud, Eric Lippert
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Atypical Myeloproliferative Neoplasms (aMPN) share characteristics of MPN and Myelodysplastic Syndromes. Although abnormalities in cytokine signaling are common in MPN, the pathophysiology of atypical MPN still remains elusive. Si
Externí odkaz:
https://doaj.org/article/4794d25d55f54eb09f7966c3979775b0
Autor:
Carlo Stephan Jackson, Chrisna Durandt, Ilse Janse van Rensburg, Vincent Praloran, Philippe Brunet de la Grange, Michael Sean Pepper
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 124-131 (2017)
Culture conditions used for the expansion of hematopoietic stem and progenitor cells (HSCs and HPCs, collectively HSPCs) should ideally favor the self renewal of long-term HSCs. At 20% O2, the synthesis of HIF-1α is balanced by its hydroxylation and
Externí odkaz:
https://doaj.org/article/f2adcef4b1d64c1a9bce91d593a0c484
Autor:
Laura Rodriguez, Pascale Duchez, Nicolas Touya, Christelle Debeissat, Amélie V. Guitart, Jean-Max Pasquet, Marija Vlaski-Lafarge, Philippe Brunet de la Grange, Zoran Ivanovic
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 558 (2021)
Alpha tocopherol acetate (αTOA) is an analogue of alpha tocopherol (αTOC) that exists in the form of an injectable drug. In the context of the metabolic hypothesis of stem cells, we studied the impact of αTOA on the metabolic energetic profile and
Externí odkaz:
https://doaj.org/article/07711e9f716f41cb8dec20444779abdf
Autor:
Véronique Lapostolle, Jean Chevaleyre, Pascale Duchez, Laura Rodriguez, Marija Vlaski-Lafarge, Ioanna Sandvig, Philippe Brunet de la Grange, Zoran Ivanovic
Publikováno v:
Haematologica, Vol 103, Iss 10 (2018)
The feasibility of ex vivo expansion allows us to consider the steady-state peripheral blood as an alternative source of hematopoietic stem progenitor cells for transplantation when growth factor-induced cell mobilization is contraindicated or inappl
Externí odkaz:
https://doaj.org/article/ef77fbd9988b4157a7ee4ad0437275cb
Autor:
Olivier Féraud, Yannick Valogne, Michael W Melkus, Yanyan Zhang, Noufissa Oudrhiri, Rima Haddad, Aurélie Daury, Corinne Rocher, Aniya Larbi, Philippe Duquesnoy, Dominique Divers, Emilie Gobbo, Philippe Brunet de la Grange, Fawzia Louache, Annelise Bennaceur-Griscelli, Maria Teresa Mitjavila-Garcia
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149291 (2016)
Hematopoiesis generated from human embryonic stem cells (ES) and induced pluripotent stem cells (iPS) are unprecedented resources for cell therapy. We compared hematopoietic differentiation potentials from ES and iPS cell lines originated from variou
Externí odkaz:
https://doaj.org/article/14bfd02e2fb14211b51eee3337d975a5
Autor:
Pascale Duchez, Jean Chevaleyre, Philippe Brunet De La Grange, Marija Vlaski, Jean-Michel Boiron, Zoran Ivanovic Ph.D.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Our previously published ex vivo expansion procedure starting from cord blood CD34 + cells enables a massive expansion of total and CD34 + cells and committed progenitors without negative impact on stem cells exhibiting both short- and long-term repo
Externí odkaz:
https://doaj.org/article/dc2146aa0adb49c29763fad5b1fa24ec
Autor:
Jean Chevaleyre, Pascale Duchez, Laura Rodriguez, Marija Vlaski, Arnaud Villacreces, Véronique Conrad-Lapostolle, Vincent Praloran, Zoran Ivanovic, Philippe Brunet de la Grange
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74361 (2013)
BACKGROUND: Xenotransplantation models allowing the identification and quantification of human Hematopoietic stem cells (HSC) in immunodeficient mice remain the only way to appropriately address human HSC function despite the recent progress in pheno
Externí odkaz:
https://doaj.org/article/86437144264c46feb691dc992ef42a91