Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Philippe Bourassa"'
Autor:
Louise Reveret, Manon Leclerc, Vincent Emond, Cyntia Tremblay, Andréanne Loiselle, Philippe Bourassa, David A. Bennett, Sébastien S. Hébert, Frédéric Calon
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Cognitive decline due to Alzheimer’s disease (AD) is frequent in the geriatric population, which has been disproportionately affected by the COVID-19 pandemic. In this study, we investigated the levels of angiotensin-converting enzyme 2 (A
Externí odkaz:
https://doaj.org/article/35a368b7de5c46d7b1fd90b978430f40
Autor:
Louise Reveret, Manon Leclerc, Vincent Emond, Cyntia Tremblay, Andréanne Loiselle, Philippe Bourassa, David A. Bennett, Sébastien S. Hébert, Frédéric Calon
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d66d4ecc4c204affb1fb8f3919f53438
Autor:
Marine Tournissac, Philippe Bourassa, Ruben D. Martinez-Cano, Tra-My Vu, Sébastien S. Hébert, Emmanuel Planel, Frédéric Calon
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 110-120 (2019)
Objective: Old age is associated with a rise in the incidence of Alzheimer's disease (AD) but also with thermoregulatory deficits. Indicative of a link between the two, hypothermia induces tau hyperphosphorylation. The 3xTg-AD mouse model not only de
Externí odkaz:
https://doaj.org/article/0bcd444f915644ed85f9428cd99fc52d
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69248 (2013)
The binding sites of antitumor drug doxorubicin (DOX) and its analogue N-(trifluoroacetyl) doxorubicin (FDOX) with tRNA were located, using FTIR, CD, fluorescence spectroscopic methods and molecular modeling. Different binding sites are involved in d
Externí odkaz:
https://doaj.org/article/c8cb8decba4c4d92bb6363ca559270b1
Autor:
Amine Abderrezak, Philippe Bourassa, Jean-Sebastian Mandeville, Reza Sedaghat-Herati, Heidar-Ali Tajmir-Riahi
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33102 (2012)
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene a
Externí odkaz:
https://doaj.org/article/665f53168cd74b278d4fe7228a2a96be
Autor:
Daniel Agudelo, Philippe Bourassa, Julie Bruneau, Gervais Bérubé, Eric Asselin, Heidar-Ali Tajmir-Riahi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43814 (2012)
We located the binding sites of doxorubicin (DOX) and N-(trifluoroacetyl) doxorubicin (FDOX) with bovine serum albumin (BSA) and human serum albumins (HSA) at physiological conditions, using constant protein concentration and various drug contents. F
Externí odkaz:
https://doaj.org/article/7fd5ff201cce4d728f225aa1ade3e88d
Autor:
Milene Vandal, Adam Institoris, Ben Korin, Colin Gunn, Lee Suzie, Jiyeon Lee, Philippe Bourassa, Ramesh Mishra, Govind Peringod, Yulan Jiang, Sotaro Hirai, Camille Belzil, Louise Reveret, Cyntia Tremblay, Mada Hashem, William Meilandt, Oded Foreman, Meron Rouse-Girma, Wilten Nicola, Jakob Körbelin, Jeff F. Dunn, Andrew Braun, David Bennett, Grant Gordon, Frédéric Calon, Andrey Shaw, Minh Dang Nguyen
Genetic variations in CD2-associated protein (CD2AP) predispose to Alzheimer’s disease (AD) but the underlying mechanisms remain unknown. Here, we show that a cerebrovascular loss of CD2AP in AD is associated with cognitive decline and genetic down
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d4992409ad8fa52795db5da442d82fa
https://doi.org/10.21203/rs.3.rs-1806158/v1
https://doi.org/10.21203/rs.3.rs-1806158/v1
Autor:
Frédéric Calon, Philippe Bourassa, Manon Leclerc, C. Sugere, Cyntia Tremblay, V. Emond, V. Caron, David A. Bennett
Publikováno v:
Brain : a journal of neurology.
Central response to insulin is suspected to be defective in Alzheimer’s disease (AD), but its localization in the brain remains unknown. While most insulin is secreted in the bloodstream by the pancreas, how it interacts with the blood-brain barrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa52832d78333cfa1b19318ce64a9e6
https://pubmed.ncbi.nlm.nih.gov/36402144
https://pubmed.ncbi.nlm.nih.gov/36402144
Publikováno v:
Neuropathol Appl Neurobiol
Aims Brain mural cells (BMC), smooth muscle cells and pericytes, interact closely with endothelial cells and modulate numerous cerebrovascular functions. A loss of BMC function is suspected to play a role in the pathophysiology of Alzheimer's Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41927e2edd0782a6608fae8bbae0cef
https://doi.org/10.1111/nan.12599
https://doi.org/10.1111/nan.12599
Autor:
Louise Reveret, Manon Leclerc, Vincent Emond, Andréanne Loiselle, Philippe Bourassa, Cyntia Tremblay, David A. Bennett, Sébastien Hébert, Frederic Calon
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd1c58980d64f211aa4ab6f405f363e
https://doi.org/10.1002/alz.055278
https://doi.org/10.1002/alz.055278