Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Philippe Beaune"'
Autor:
Benjamin Nayagom, Ikrame Amara, Meryem Habiballah, Floriane Amrouche, Philippe Beaune, Isabelle de Waziers
Publikováno v:
OncoImmunology, Vol 8, Iss 12 (2019)
It was previously demonstrated that engineered mesenchymal stem cells (MSCs) which express a high level of a very efficient modified gene CYP2B6* (CYP2B6TM-RED) acting as a suicide gene (MSC-2B6*) in combination with cyclophosphamide (CPA) constitute
Externí odkaz:
https://doaj.org/article/ab206c7ff3be493893662c131cca50e0
Publikováno v:
Tic & Société, Vol 12, Iss 1, Pp 255-281 (2018)
Can open data be considered as common goods? The work to pre-process or edit data in order to make them available on cities’ open data portals transforms them into shared resources. As such they seem to have the potential of being a common good. Ho
Externí odkaz:
https://doaj.org/article/a22f0db75ec14da5883fcc2c8e36d8cf
Publikováno v:
International Journal of Digital Earth, Vol 10, Iss 9, Pp 901-922 (2017)
Spatial online analytical processing (OLAP) and spatial data warehouse (SDW) systems are geo-business intelligence technologies that enable the analysis of huge volumes of geographic data. In the last decade, the conceptual design and implementation
Externí odkaz:
https://doaj.org/article/03d9cf7390594cc1958f962d43f04c54
Autor:
Céline Narjoz, Amélie Favre, Justin McMullen, Philippe Kiehl, Michael Montemurro, William D Figg, Philippe Beaune, Isabelle de Waziers, Bertrand Rochat
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95532 (2014)
We have investigated in vitro the metabolic capability of 3 extrahepatic cytochromes P-450, CYP1A1, 1B1 and 2J2, known to be over-expressed in various tumors, to biotransform 5 tyrosine kinase inhibitors (TKI): dasatinib, imatinib, nilotinib, sorafen
Externí odkaz:
https://doaj.org/article/d21312ddee844f25aa3d81c27af1a523
Autor:
Nicolas Pallet, Sophie Chauvet, Jean-François Chassé, Marc Vincent, Paul Avillach, Charlene Levi, Vannary Meas-Yedid, Jean-Christophe Olivo-Marin, Diane Nga-Matsogo, Philippe Beaune, Eric Thervet, Alexandre Karras
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84708 (2014)
Currently, a non-invasive method to estimate the degree of interstitial fibrosis (IF) in chronic kidney disease is not available in routine. The aim of our study was to evaluate the diagnostic performance of the measurement of urinary low molecular w
Externí odkaz:
https://doaj.org/article/1a198313d7e84772a8f8004ac4d73126
Autor:
Antoine Neuraz, Laurent Chouchana, Georgia Malamut, Christine Le Beller, Denis Roche, Philippe Beaune, Patrice Degoulet, Anita Burgun, Marie-Anne Loriot, Paul Avillach
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 12, p e1003405 (2013)
Phenome-Wide Association Studies (PheWAS) investigate whether genetic polymorphisms associated with a phenotype are also associated with other diagnoses. In this study, we have developed new methods to perform a PheWAS based on ICD-10 codes and biolo
Externí odkaz:
https://doaj.org/article/c86ab7f31a3b422e9a1d2ce6672ce866
Autor:
Emmanuelle Girard, Jean Louis Paul, Natalie Fournier, Philippe Beaune, Ludger Johannes, Christophe Lamaze, Benoît Védie
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29042 (2011)
Intracellular transport of cholesterol contributes to the regulation of cellular cholesterol homeostasis by mechanisms that are yet poorly defined. In this study, we characterized the impact of dynasore, a recently described drug that specifically in
Externí odkaz:
https://doaj.org/article/06c75887135343ca99e7cd435ced73ef
Autor:
Rajagopal Krishnamoorthy, Philippe Beaune, Marion Leboyer, Ryad Tamouza, Bruno O. Villoutreix
Publikováno v:
Advances and Applications in Bioinformatics and Chemistry : AABC
Advances and applications in bioinformatics and chemistry
Advances and applications in bioinformatics and chemistry, Dove Medical Press Ltd., 2021, Volume 14, pp.71-85. ⟨10.2147/AABC.S304649⟩
Advances and applications in bioinformatics and chemistry, 2021, Volume 14, pp.71-85. ⟨10.2147/AABC.S304649⟩
Advances and applications in bioinformatics and chemistry
Advances and applications in bioinformatics and chemistry, Dove Medical Press Ltd., 2021, Volume 14, pp.71-85. ⟨10.2147/AABC.S304649⟩
Advances and applications in bioinformatics and chemistry, 2021, Volume 14, pp.71-85. ⟨10.2147/AABC.S304649⟩
Bruno O Villoutreix,1 Rajagopal Krishnamoorthy,2 Ryad Tamouza,2 Marion Leboyer,2 Philippe Beaune3 1INSERM U1141, NeuroDiderot, Université de Paris, Hôpital Robert-Debré, Paris, F-75019, France; 2Université Paris Est Créteil, INSERM U955, IMRB, L
Autor:
Marc Sapoval, Carole Déan, Tchao Méachi, Philippe Beaune, Isabelle de Waziers, Olivier Pellerin, Ikram Amara
Publikováno v:
CardioVascular and Interventional Radiology. 41:153-162
Gene-directed enzyme prodrug therapy (GDEPT) is a “Trojan-horses” suicide gene therapy that consists of tumor-targeted gene delivery (vectorized by mesenchymal stem cells MSCs) encoding an enzyme that converts a harmless prodrug into cytotoxic me
Autor:
Clara Gitahy Falcao Faria, Coraline Hingray, Ángel Ruiz De Pellon Santamaria, Bruno O. Villoutreix, Hervé Javelot, Philippe Beaune, Julien Petrignet, Marion Leboyer, Luisa Weiner
Publikováno v:
Medical Hypotheses
Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus e