Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Philippe Barthélémy"'
Autor:
Laurence Buisseret, Delphine Loirat, Philippe Aftimos, Christian Maurer, Kevin Punie, Véronique Debien, Paulus Kristanto, Daniel Eiger, Anthony Goncalves, François Ghiringhelli, Donatienne Taylor, Florent Clatot, Tom Van den Mooter, Jean-Marc Ferrero, Hervé Bonnefoi, Jean-Luc Canon, Francois P. Duhoux, Laura Mansi, Renaud Poncin, Philippe Barthélémy, Nicolas Isambert, Zoë Denis, Xavier Catteau, Roberto Salgado, Elisa Agostinetto, Evandro de Azambuja, Françoise Rothé, Ligia Craciun, David Venet, Emanuela Romano, John Stagg, Marianne Paesmans, Denis Larsimont, Christos Sotiriou, Michail Ignatiadis, Martine Piccart-Gebhart
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Chemo-immunotherapy is the first-line standard of care for patients with PD-L1 positive metastatic triple-negative breast cancer (mTNBC). SYNERGY (NCT03616886) is a dose-finding phase I and a randomized phase II, open-label trial evaluating
Externí odkaz:
https://doaj.org/article/50f0c9a693404d0bbb0bf5ae3d4ee9c1
Autor:
Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100172- (2023)
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotr
Externí odkaz:
https://doaj.org/article/76fd39d35eed4b10bc8fe7a5d38243bc
Autor:
Laurence Buisseret, Delphine Loirat, Philippe Aftimos, Christian Maurer, Kevin Punie, Véronique Debien, Paulus Kristanto, Daniel Eiger, Anthony Goncalves, François Ghiringhelli, Donatienne Taylor, Florent Clatot, Tom Van den Mooter, Jean-Marc Ferrero, Hervé Bonnefoi, Jean-Luc Canon, Francois P. Duhoux, Laura Mansi, Renaud Poncin, Philippe Barthélémy, Nicolas Isambert, Zoë Denis, Xavier Catteau, Roberto Salgado, Elisa Agostinetto, Evandro de Azambuja, Françoise Rothé, Ligia Craciun, David Venet, Emanuela Romano, John Stagg, Marianne Paesmans, Denis Larsimont, Christos Sotiriou, Michail Ignatiadis, Martine Piccart-Gebhart
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1872bd3c329443328fa10ee0e5e38651
Autor:
Alexandre Derre, Noelian Soler, Valentine Billoux, Sebastien Benizri, Brune Vialet, Cyril Rivat, Philippe Barthélémy, Patrick Carroll, Alexandre Pattyn, Stephanie Venteo
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Chronic pain, whether of inflammatory or neuropathic origin, affects about 18% of the population of developed countries, and most current treatments are only moderately effective and/or cause serious side effects. Therefore, the development of novel
Externí odkaz:
https://doaj.org/article/12668065e27441908f0e18635bd35a29
Autor:
Claire Masson, Jonathan Thouvenin, Philippe Boudier, Denis Maillet, Sabine Kuchler-Bopp, Philippe Barthélémy, Thierry Massfelder
Publikováno v:
Cancers, Vol 15, Iss 12, p 3159 (2023)
Renal cell carcinoma (RCC) represents around 2% of cancer-related deaths worldwide per year. RCC is an immunogenic malignancy, and treatment of metastatic RCC (mRCC) has greatly improved since the advent of the new immunotherapy agents, including imm
Externí odkaz:
https://doaj.org/article/de0c5dc8dcd94cc3a3f28ad1d6a8b89b
Autor:
Jonathan Thouvenin, Claire Masson, Philippe Boudier, Denis Maillet, Sabine Kuchler-Bopp, Philippe Barthélémy, Thierry Massfelder
Publikováno v:
Cancers, Vol 15, Iss 3, p 793 (2023)
Renal-cell carcinoma (RCC) accounts for 2% of cancer diagnoses and deaths worldwide. Clear-cell RCCs represent the vast majority (85%) of kidney cancers and are considered morphologically and genetically as immunogenic tumors. Indeed, the RCC tumoral
Externí odkaz:
https://doaj.org/article/aef9ef00ed95431ab60209355b3b445a
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24746-24753 (2020)
Externí odkaz:
https://doaj.org/article/cfa0bea359bf4b3184cbc54577971772
Autor:
Anthony Cunha, Geoffrey Prévot, Yannick Mousli, Philippe Barthélémy, Sylvie Crauste-Manciet, Benjamin Dehay, Valérie Desvergnes
Publikováno v:
ACS Omega, Vol 5, Iss 11, Pp 5815-5823 (2020)
Externí odkaz:
https://doaj.org/article/52e8c80be5244e15a2aa71633d6207e9
Autor:
Phuoc Vinh Nguyen, Clémentine Aubry, Narimane Boudaoud, Alexandra Gaubert, Marie-Hélène Langlois, Mathieu Marchivie, Karen Gaudin, Corinne Arpin, Philippe Barthélémy, Tina Kauss
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2317 (2022)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/d7edc7b220dc46e7bf9bb9ff92ccde06
Autor:
Mathias Brouillard, Philippe Barthélémy, Benjamin Dehay, Sylvie Crauste-Manciet, Valérie Desvergnes
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Increasing evidence suggests that lysosomal dysfunction has a pathogenic role in neurodegenerative diseases. In particular, an increase in lysosomal pH has been reported in different cellular models of Parkinson’s disease. Thus, targeting lysosomes
Externí odkaz:
https://doaj.org/article/f84109df25d44b21b1e5247ad8297b73