Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Philippe Alzieu"'
Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction
Autor:
Lauriane Cornuault, François‐Xavier Hérion, Célia Bourguignon, Paul Rouault, Ninon Foussard, Philippe Alzieu, Candice Chapouly, Alain‐Pierre Gadeau, Thierry Couffinhal, Marie‐Ange Renault
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background Although the critical role of pericytes in maintaining vascular integrity has been extensively demonstrated in the brain and the retina, little is known about their role in the heart. We aim to investigate structural and functional consequ
Externí odkaz:
https://doaj.org/article/f9b64fa08d394f60b43870a709597c09
Autor:
Clement Karsenty, Celine Guilbeau-Frugier, Gaël Genet, Marie-Helene Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julile Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Senard, Celine Galés
Publikováno v:
eLife, Vol 12 (2023)
The rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role. Here, we investigated the development and functional ro
Externí odkaz:
https://doaj.org/article/4a1c47633a1c414d92ff3c8bf4e59cf3
Autor:
Clement Karsenty, Celine Guilbeau-Frugier, Gaël Genet, Marie-Helene Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julile Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Senard, Celine Galés
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1634c134604e583971dbb7141e94d870
https://doi.org/10.7554/elife.80904.sa2
https://doi.org/10.7554/elife.80904.sa2
Cardiac pericytes are necessary for coronary vasculature integrity and cardiomyocyte differentiation
Autor:
Lauriane Cornuault, François-Xavier Hérion, Paul Rouault, Ninon Foussard, Philippe Alzieu, Candice Chapouly, Alain-Pierre Gadeau, Thierry Couffinhal, Marie-Ange Renault
Introduction: While the critical role of pericytes in maintaining vascular integrity has been extensively demonstrated in the brain and in the retina, very little is known about their role in the heart. Objective: We aim to investigate structural and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8e7d674de5848b8c0460a68ba38415d
https://doi.org/10.1101/2022.08.29.505703
https://doi.org/10.1101/2022.08.29.505703
Autor:
Clément Karsenty, Céline Guilbeau-Frugier, Gaël Genet, Marie-Hélène Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julie Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Sénard, Céline Galés
RATIONALEIn addition to its typical rod-shape, the mammalian adult cardiomyocyte (CM) harbors a unique lateral membrane surface architecture with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) the role of which is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9ca0861f7991a1193cdb1efac80fc7
https://doi.org/10.1101/2022.02.11.480042
https://doi.org/10.1101/2022.02.11.480042
Autor:
Cécile Duplàa, Laurent Barandon, Danièle Daret, Thierry Couffinhal, Claude Deville, Philippe Alzieu, Pascale Dufourcq
Publikováno v:
The Annals of Thoracic Surgery. 78:1409-1417
Background Myocardial infarction results in irreversible myocyte loss. In a murine model, we tested the feasibility of a novel repair technique combining bone marrow cell (BMC) transplantation and cardiomyoplasty. Methods Myocardial infarction was in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1144dd8b83f23ca3f5f607b4364c51
https://doi.org/10.1016/j.athoracsur.2003.12.078
https://doi.org/10.1016/j.athoracsur.2003.12.078
Autor:
Danièle Daret, Thierry Couffinhal, Philippe Alzieu, Cécile Duplàa, Pascale Dufourcq, Cécile Allières, Béatrice Jaspard, Patrick Serre, Jacques Bonnet
Publikováno v:
Coronary Artery Disease. 12:635-648
Discrepancies between success in experimental animals with a variety of pharmacologic strategies and failure with such agents in clinical trials have raised questions concerning the mechanism of restenosis. Recent observations suggest a potential imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273dd14a75ed2ac4dd76b76119e2042c
https://doi.org/10.1097/00019501-200112000-00007
https://doi.org/10.1097/00019501-200112000-00007
Autor:
Daniele Rovai, Raymond Roudaut, Simone Bonoron, Pierre Besse, Patrick Laffort, Philippe Alzieu, Stéphane Lafitte
Publikováno v:
Echocardiography. 15:563-573
BACKGROUND: New echocardiographic contrast agents are commonly tested in the dog model. However, this species has a number of drawbacks, including difficulties in experimentation, cost, and ethical considerations. The rabbit has a number of advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5271e9f29cf90fe5430255c261f70c36
https://doi.org/10.1111/j.1540-8175.1998.tb00648.x
https://doi.org/10.1111/j.1540-8175.1998.tb00648.x
Autor:
Cheikh I. Seye, Danièle Daret, Françoise Dupuch, Philippe Alzieu, Loïc Capron, Alain-Pierre Gadeau, Claude Desgranges
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:3602-3610
Abstract Extracellular nucleotides, particularly ATP, are involved in the modulation of arterial vasomotricity via P2 purinoceptors present on smooth muscle and endothelial cells. These nucleotides could also be implicated in the smooth muscle cell h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56798234408fcc170acc926f4af949f6
https://doi.org/10.1161/01.atv.17.12.3602
https://doi.org/10.1161/01.atv.17.12.3602
Autor:
Laurent, Barandon, Thierry, Couffinhal, Pascale, Dufourcq, Philippe, Alzieu, Catherine, Moreau, Daniéle, Daret, Cécile, Duplàa
Publikováno v:
The Canadian journal of cardiology. 21(7)
Cellular cardiomyoplasty has created new possibilities in cardiac regeneration. Several cell types can be used in the procedure, such as skeletal myoblasts and bone marrow cells. Recent publications have suggested that bone marrow cells may be excell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83175a5087def3b06da928d4cecef98a
https://pubmed.ncbi.nlm.nih.gov/15940353
https://pubmed.ncbi.nlm.nih.gov/15940353