Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Philippe A. Hasgall"'
Autor:
Philippe A Hasgall, David Hoogewijs, Marius B Faza, Vikram G Panse, Roland H Wenger, Gieri Camenisch
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22107 (2011)
The hypoxia-inducible transcription factor (HIF) is a key component of the cellular adaptation mechanisms to hypoxic conditions. HIFα subunits are degraded by prolyl-4-hydroxylase domain (PHD) enzyme-dependent prolyl-4-hydroxylation of LxxLAP motifs
Externí odkaz:
https://doaj.org/article/556484b79578488781c6b64f2eb71a06
Autor:
Günther Jahreis, Joachim Fandrey, Silke Gneuss, Gieri Camenisch, Sandra Barth, Roland H. Wenger, Frank Edlich, Utta Berchner-Pfannschmidt, Philippe A. Hasgall
Publikováno v:
The Journal of biological chemistry. 284(34)
Prolyl-4-hydroxylase domain (PHD) proteins are 2-oxoglutarate and dioxygen-dependent enzymes that mediate the rapid destruction of hypoxia-inducible factor alpha subunits. Whereas PHD1 and PHD3 proteolysis has been shown to be regulated by Siah2 ubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30002796e718cb64987c1c9ba40ecd26
https://pubmed.ncbi.nlm.nih.gov/19546213
https://pubmed.ncbi.nlm.nih.gov/19546213
Autor:
Jutta Nesper, Renato Wirthner, Daniel P. Stiehl, Frank Edlich, Gieri Camenisch, Philippe A. Hasgall, Katarzyna J. Nytko, Sandra Barth, Dörthe M. Katschinski, Roland H. Wenger
The heterodimeric hypoxia-inducible transcription factors (HIFs) are central regulators of the response to low oxygenation. HIF-alpha subunits are constitutively expressed but rapidly degraded under normoxic conditions. Oxygen-dependent hydroxylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d73bb7cf0e5f580406b19c6f067d467
https://europepmc.org/articles/PMC1899990/
https://europepmc.org/articles/PMC1899990/
Autor:
Marius Boulos Faza, David Hoogewijs, Gieri Camenisch, Roland H. Wenger, Vikram Govind Panse, Philippe A. Hasgall
Publikováno v:
PloS one
PLoS ONE, 6 (7)
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22107 (2011)
PLoS ONE, 6 (7)
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22107 (2011)
The hypoxia–inducible transcription factor (HIF) is a key component of the cellular adaptation mechanisms to hypoxic conditions. HIFα subunits are degraded by prolyl-4-hydroxylase domain (PHD) enzyme-dependent prolyl-4-hydroxylation of LxxLAP moti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a57b89097f668ed987c1b42f03392b