Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication.

Autor: Adele R; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Hussein R; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Tavares E; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Ahmed K; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Di Scipio M; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Charish J; Vision Division, Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada., Liang M; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto (U of T), Toronto, Ontario, Canada., Monis S; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto (U of T), Toronto, Ontario, Canada., Tumber A; Department of Ophthalmology and Visual Sciences and., Chen X; Vision Division, Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada., Paton TA; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada.; The Centre for Applied Genomics, HSC, Toronto, Ontario, Canada., Roslin NM; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Eileen C; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Ivakine E; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Sunny NE; Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland, USA., Wilson MD; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Campos E; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Rajala RV; Departments of Ophthalmology, Physiology, and Cell Biology and Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Maynes JT; Molecular Medicine program and.; Department of Anesthesia and Pain Medicine, HSC, Toronto, Ontario, Canada., Monnier PP; Vision Division, Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.; Department of Physiology, Faculty of Medicine, and., Paterson AD; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada., Héon E; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada.; Department of Ophthalmology and Visual Sciences and.; Department of Ophthalmology and Visual Sciences, U of T, Toronto, Ontario, Canada., Vincent A; Genetics & Genome Biology program, Hospital for Sick Children (HSC), Toronto, Ontario, Canada.; Department of Ophthalmology and Visual Sciences and.; Department of Ophthalmology and Visual Sciences, U of T, Toronto, Ontario, Canada.

Publikováno v: JCI insight [JCI Insight] 2024 Dec 06; Vol. 9 (23). Date of Electronic Publication: 2024 Dec 06.

Functional characterization of optic photoreception in Lymnaea stagnalis.

Autor: Harracksingh AN; Departments of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Bandura J; Departments of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Morizumi T; Department of Biochemistry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Monnier PP; Departments of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Ophthalmology and Vision Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Henderson JT; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada., Feng ZP; Departments of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Publikováno v: PloS one [PLoS One] 2024 Nov 12; Vol. 19 (11), pp. e0313407. Date of Electronic Publication: 2024 Nov 12 (Print Publication: 2024).

Microbiota signature of oral chronic graft-versus-host disease 6+ years after transplantation.

Autor: Rashidi A; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA. arashidi@fredhutch.org., Liang L; Harvard School of Dental Medicine, Boston, MA., Gooley T; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA., Hujoel PP; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA; Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA., Zevin A; Genomics and Bioinformatics Shared Resource, Fred Hutchinson Cancer Center, Seattle, WA., Rothen M; University of Washington School of Dentistry, Seattle, WA., Hagstrom MK; University of Washington School of Dentistry, Seattle, WA., Cutler C; Dana-Farber Cancer Institute, Boston, MA., Lee SJ; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA., Dean DR; Department of Oral Medicine, University of Washington and Fred Hutchinson Cancer Center, Seattle, WA., Sroussi HY; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA; Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA., Treister NS; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA; Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA.

Publikováno v: Haematologica [Haematologica] 2024 Nov 01; Vol. 109 (11), pp. 3800-3805. Date of Electronic Publication: 2024 Nov 01.

Mesenchymal-like immune-altered is the fourth robust triple-negative breast cancer molecular subtype.

Autor: Jézéquel P; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France. pascal.jezequel@ico.unicancer.fr.; Nantes Université, Univ Angers, INSERM, CNRS, CRCI2NA, 44000, Nantes, France. pascal.jezequel@ico.unicancer.fr.; Équipe Labellisée LIGUE Contre Le Cancer CRCI2NA, 44000, Nantes, France. pascal.jezequel@ico.unicancer.fr., Lasla H; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France., Gouraud W; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France., Basseville A; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France., Michel B; Nantes Université, École Centrale Nantes, CNRS, Laboratoire de Mathématiques Jean Leray, LMJL, UMR 6629, 44000, Nantes, France., Frenel JS; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France.; Nantes Université, Univ Angers, INSERM, CNRS, CRCI2NA, 44000, Nantes, France.; Équipe Labellisée LIGUE Contre Le Cancer CRCI2NA, 44000, Nantes, France., Juin PP; Nantes Université, Univ Angers, INSERM, CNRS, CRCI2NA, 44000, Nantes, France.; Équipe Labellisée LIGUE Contre Le Cancer CRCI2NA, 44000, Nantes, France., Ben Azzouz F; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France., Campone M; Institut de Cancérologie de l'Ouest, 44805, Saint Herblain, France.; Nantes Université, Univ Angers, INSERM, CNRS, CRCI2NA, 44000, Nantes, France.; Équipe Labellisée LIGUE Contre Le Cancer CRCI2NA, 44000, Nantes, France.; Université d'Angers, 49000, Angers, France.

Publikováno v: Breast cancer (Tokyo, Japan) [Breast Cancer] 2024 Sep; Vol. 31 (5), pp. 825-840. Date of Electronic Publication: 2024 May 22.

Single-cell atlas of the human brain vasculature across development, adulthood and disease.

Autor: Wälchli T; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. thomas.waelchli2@uzh.ch.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada. thomas.waelchli2@uzh.ch.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland. thomas.waelchli2@uzh.ch.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland. thomas.waelchli2@uzh.ch., Ghobrial M; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.; Laboratory of Exercise and Health, Institute of Exercise and Health, Department of Health Sciences and Technology; Swiss Federal Institute of Technology (ETH Zurich), Zurich, Switzerland., Schwab M; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.; Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland., Takada S; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada., Zhong H; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.; Laboratory of Exercise and Health, Institute of Exercise and Health, Department of Health Sciences and Technology; Swiss Federal Institute of Technology (ETH Zurich), Zurich, Switzerland., Suntharalingham S; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Vetiska S; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada., Gonzalez DR; Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland., Wu R; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Rehrauer H; Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland., Dinesh A; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Health System, Toronto, Ontario, Canada., Yu K; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Chen ELY; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Bisschop J; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Farnhammer F; Group Brain Vasculature and Perivascular Niche, Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Mansur A; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Kalucka J; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Tirosh I; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Regli L; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland., Schaller K; Department of Neurosurgery, University of Geneva Medical Center & Faculty of Medicine, University of Geneva, Geneva, Switzerland., Frei K; Group of CNS Angiogenesis and Neurovascular Link, Neuroscience Center Zurich, University of Zurich and University Hospital Zurich, Zurich, Switzerland.; Division of Neurosurgery, University Hospital Zurich, Zurich, Switzerland., Ketela T; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Bernstein M; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Sprott Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Kongkham P; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Sprott Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; MacFeeters-Hamilton Centre for Neuro-Oncology Research, University Health Network, Toronto, Ontario, Canada., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB & Department of Oncology, KU Leuven, Leuven, Belgium.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, P. R. China.; Laboratory of Angiogenesis and Vascular Heterogeneity, Department of Biomedicine, Aarhus University, Aarhus, Denmark., Valiante T; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Sprott Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Krembil Brain Institute, Division of Clinical and Computational Neuroscience, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Institute of Biomaterials and Biomedical Engineering and Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada.; Institute of Medical Science Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Dirks PB; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Center, Departments of Surgery and Molecular Genetics, Hospital for Sick Children, Toronto, Ontario, Canada., Suva ML; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Zadeh G; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Sprott Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Tabar V; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schlapbach R; Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland., Jackson HW; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Ontario Institute of Cancer Research, Toronto, Ontario, Canada., De Bock K; Laboratory of Exercise and Health, Institute of Exercise and Health, Department of Health Sciences and Technology; Swiss Federal Institute of Technology (ETH Zurich), Zurich, Switzerland., Fish JE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.; Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada., Monnier PP; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Krembil Research Institute, Vision Division, Krembil Discovery Tower, Toronto, Ontario, Canada.; Department of Ophthalmology and Vision Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Bader GD; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada., Radovanovic I; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; Division of Experimental and Translational Neuroscience, Krembil Brain Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, Sprott Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

Publikováno v: Nature [Nature] 2024 Aug; Vol. 632 (8025), pp. 603-613. Date of Electronic Publication: 2024 Jul 10.