Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Philippe, Lawton"'
Autor:
Valentine Tingaud, Claire Bordes, Eyad Al Mouazen, Claudia Cogné, Marie-Alexandrine Bolzinger, Philippe Lawton
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Background To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow well on mammalian cells. The avian suspension cell line DuckCelt®-T17 was previously studi
Externí odkaz:
https://doaj.org/article/61c65d05652742079a387816c79ba59e
Autor:
Marine Leroux, Hana Bouazizi‐Ben Messaoud, Céline Luquain‐Costaz, Lars P. Jordheim, Pauline Le Faouder, Marie‐Paule Gustin, Karim Aoun, Philippe Lawton, Samira Azzouz‐Maache, Isabelle Delton
Publikováno v:
Lipids. 58:81-92
Autor:
Valentine Tingaud, Claire Bordes, Eyad Al Mouazen, Claudia Cogné, Marie-Alexandrine Bolzinger, Philippe Lawton
Background To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow well on mammalian cells. The avian suspension cell line DuckCelt®-T17 was previously studied and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d048896dd531f03b3039ab24fb6d3e02
https://doi.org/10.21203/rs.3.rs-2459112/v1
https://doi.org/10.21203/rs.3.rs-2459112/v1
Autor:
Marine, Leroux, Hana, Bouazizi-Ben Messaoud, Céline, Luquain-Costaz, Lars P, Jordheim, Pauline, Le Faouder, Marie-Paule, Gustin, Karim, Aoun, Philippe, Lawton, Samira, Azzouz-Maache, Isabelle, Delton
Publikováno v:
Lipids
Lipids, 2023, 58 (2), pp.81-92. ⟨10.1002/lipd.12365⟩
Lipids, 2023, 58 (2), pp.81-92. ⟨10.1002/lipd.12365⟩
Leishmania parasites are the causative agents of visceral or cutaneous leishmaniasis in humans and of canine leishmaniosis. The macrophage is the predilected host cell of Leishmania in which the promastigote stage is transformed into amastigote. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f1c06c8fba26809186d1985b044499f3
https://hal.science/hal-04158694/document
https://hal.science/hal-04158694/document
Autor:
Samira Azzouz-Maache, Marine Leroux, Uruguaysito benavides, imane Hellel-Bourtal, cecilia Silvarrey, nadège milhau, thierry marchal, philippe lawton, stéphanie Briançon, Anne-Françoise petavy, samia lahmar, adriana esteves, eyad almouazen
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
International Journal of Molecular Sciences. 24:4702
Fatty acids have received growing interest in Leishmania biology with the characterization of the enzymes allowing the complete fatty acid synthesis of this trypanosomatid parasite. This review presents a comparative analysis of the fatty acid profil
Autor:
Erica S Martins-Duarte, Faustine Dubar, Philippe Lawton, Cristiane França da Silva, Maria de Nazaré C Soeiro, Wanderley de Souza, Christophe Biot, Rossiane C Vommaro
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125705 (2015)
Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital malformations in newborns. Previously, we described the synthesis of new ethyl-ester derivatives of the
Externí odkaz:
https://doaj.org/article/130a43e894414f2db6acdf90c3566db5
Autor:
Samira Azzouz-Maache, Isabelle Delton, Marion Guichard, Philippe Lawton, Hana Bouazizi-Ben Messaoud
Publikováno v:
Lipids
Lipids, Springer Verlag, 2017, 52 (5), pp.433-441. ⟨10.1007/s11745-017-4233-6⟩
Lipids, 2017, 52 (5), pp.433-441. ⟨10.1007/s11745-017-4233-6⟩
Lipids, Springer Verlag, 2017, 52 (5), pp.433-441. ⟨10.1007/s11745-017-4233-6⟩
Lipids, 2017, 52 (5), pp.433-441. ⟨10.1007/s11745-017-4233-6⟩
International audience; Leishmania sp., are trypanosomatid parasites that are phagocytized by human and animal macrophages. Transformation from the vector promastigote stage to the intracellular amastigote host cell stage is mandatory, since developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01badb488c56a8910e2cd64ccc3bb924
https://hal.archives-ouvertes.fr/hal-01848045
https://hal.archives-ouvertes.fr/hal-01848045
Autor:
Philippe Lawton, S. Azzouz
Publikováno v:
Acta Parasitologica
Acta Parasitologica, Springer Verlag, 2017, 62 (3), pp.582-588. ⟨10.1515/ap-2017-0070⟩
Acta Parasitologica, 2017, 62 (3), pp.582-588. ⟨10.1515/ap-2017-0070⟩
Acta Parasitologica, Springer Verlag, 2017, 62 (3), pp.582-588. ⟨10.1515/ap-2017-0070⟩
Acta Parasitologica, 2017, 62 (3), pp.582-588. ⟨10.1515/ap-2017-0070⟩
International audience; Inhibition of parasite metabolic pathways is a rationale for new chemotherapeutic strategies. The pyrimidine and purine salvage pathways are thus targets against Leishmania donovani and L. infantum, causative agents of viscera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815a9e357d65bb2c5427355af71b061c
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02111046/document
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02111046/document
Autor:
Philippe Lawton
Publikováno v:
Expert Opinion on Therapeutic Patents. 15:987-994
As parasites cannot synthesise purines de novo and must salvage them from their hosts, purine salvage pathways have long been considered an attractive chemotherapeutic target. Recently, the discovery of specific transition-state inhibitors, the inter