Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Philippa Meiser"'
1
Akademický článek
Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity
Autor: Anna-Marie Pedde, Hyunu Kim, Sainitin Donakonda, Tobias Baumann, Felix Bayerl, Philippa Meiser, Anna Hirschberger, Christine Klement, Simon Grassmann, Rupert Öllinger, Norbert Hüser, Daniel Hartmann, Melanie Laschinger, Joseph A. Trapani, Alfred Zippelius, Tobias Bald, Gabriela M. Wiedemann, Roland Rad, Joseph C. Sun, Bastian Höchst, Jan P. Böttcher
Publikováno v: Cell Reports, Vol 43, Iss 11, Pp 114855- (2024)
Summary: Natural killer (NK) cells are critical for anti-metastatic immunity and can eliminate metastasizing tumor cells within circulation and sites of metastatic seeding. Here, we show that disseminated tumor cells (DTCs) colonizing the mouse lung
Externí odkaz: https://doaj.org/article/f59733942ee14e7693060de6e6edd91a
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2
Akademický článek
Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation
Autor: Kira L. Diehl, Julia Vorac, Kristina Hofmann, Philippa Meiser, Iris Unterweger, Lars Kuerschner, Heike Weighardt, Irmgard Förster, Christoph Thiele
Publikováno v: Cells, Vol 9, Iss 10, p 2258 (2020)
A high fat Western-style diet leads to hepatic steatosis that can progress to steatohepatitis and ultimately cirrhosis or liver cancer. The mechanism that leads to the development of steatosis upon nutritional overload is complex and only partially u
Externí odkaz: https://doaj.org/article/ecaa38c5525f47eeb4b81ad960eb914b
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7
Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation
Autor: Iris Unterweger, Heike Weighardt, Irmgard Förster, Kira L Diehl, Kristina Hofmann, Christoph Thiele, Julia Vorac, Philippa Meiser, Lars Kuerschner
Publikováno v: Cells, Vol 9, Iss 2258, p 2258 (2020)
Cells
Volume 9
Issue 10
A high fat Western-style diet leads to hepatic steatosis that can progress to steatohepatitis and ultimately cirrhosis or liver cancer. The mechanism that leads to the development of steatosis upon nutritional overload is complex and only partially u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a47818ec944e6814be845438fcc58f6
https://doi.org/10.3390/cells9102258
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8
Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
Autor: Margriet Palm, Audrey Gérard, Philippa Meiser, Julia Braun, Simon Zenke, Jan Rohr, Niklas Beyersdorf, Stephan Ehl, Tim Lämmermann, Joost B. Beltman, Alina Gavrilov, Jan P. Böttcher, Ton N. Schumacher
Publikováno v: Immunity
Immunity, 52(2), 313-327. CELL PRESS
T cell responses upon infection display a remarkably reproducible pattern of expansion, contraction, and memory formation. If the robustness of this pattern builds entirely on signals derived from other cell types or if activated T cells themselves c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5297835ac674b65e0b8f35fa39e76562
https://doi.org/10.1016/j.immuni.2020.01.018
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