Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Philippa Kennedy"'
Autor:
Jeffrey Miller, Martin Felices, Upasana Sunil Arvindam, Brianna Ettestad, Peter Hinderlie, James Lim, Philippa Kennedy, Shee Kwan Phung, Quinlan Kile, Yunmin Li
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/764c21ed78644eb6867567de7a4bf57e
Autor:
Philippa Kennedy
An amalgamation of cell line data in the lab. Its origin and standard culture conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ddfa18e02fc7786a5e61a6cc0c9814
https://doi.org/10.17504/protocols.io.rm7vz82o8vx1/v2
https://doi.org/10.17504/protocols.io.rm7vz82o8vx1/v2
Autor:
Quinlan Kile, Upasana Sunil Arvindam, Philippa Kennedy, Peter Hinderlie, Li Yunmin, Jeffrey S. Miller, Shee Kwan Phung, Martin Felices, Brianna Ettestad, James Lim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundNatural killer (NK) cell-based immunotherapies, from biologics to cell products, are being studied in the clinic across many cancer settings. These treatments have had therapeutic success for hematological malignancies but their impact on s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2fdf367dd316b14e1f11ea35ba434a
https://doaj.org/article/764c21ed78644eb6867567de7a4bf57e
https://doaj.org/article/764c21ed78644eb6867567de7a4bf57e
Autor:
Philippa Kennedy
Publikováno v:
British Journalism Review. 31:77-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b323d49f4bee22bf037ecdb764ddfde4
https://doi.org/10.1177/0956474820931408e
https://doi.org/10.1177/0956474820931408e
Autor:
Philippa Kennedy
Assessing the capacity of IL-15 analogs (e.g. within TriKE molecules) to stimulate proliferation of NK-92 cells. NK-92 are deprived of cytokines overnight, then cultured with IL-15 analogs for two days. After this time, the expansion of viable cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cc442313eccd823846fc64bc208902
https://doi.org/10.17504/protocols.io.yxmvmxqw9l3p/v1
https://doi.org/10.17504/protocols.io.yxmvmxqw9l3p/v1
Autor:
Philippa Kennedy
Standard isolation procedure for peripheral blood mononuclear cells from human blood leukopheresis products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f697aad4b62c21df5a719038cbbf7c40
https://doi.org/10.17504/protocols.io.81wgbp94yvpk/v1
https://doi.org/10.17504/protocols.io.81wgbp94yvpk/v1
Autor:
Philippa Kennedy
Two primary functions of NK cells - their cytotoxcity and ability to produce cytokines, are measured in a flow-based assay that assesses these responses at the single cell level when NK cells are challenged with tumor cells. Cytotoxicity is not direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::106250d2483ac3d3d10fc8303052ff70
https://doi.org/10.17504/protocols.io.8epv51me6l1b/v1
https://doi.org/10.17504/protocols.io.8epv51me6l1b/v1
Autor:
Philippa Kennedy
Fluorescent target cells are plated in a monolayer in a 96 well plate. Effector cells are added to that plate and time-lapse imaging in combination with fluorescent indicators of cell death reveal the dynamics of target cell death.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbbd27f8e0ccd4b0f426090a4c4023cd
https://doi.org/10.17504/protocols.io.q26g7b6x8lwz/v1
https://doi.org/10.17504/protocols.io.q26g7b6x8lwz/v1
Autor:
Philippa Kennedy
Assessing the impact of drugs and treatments on natural killer (NK) cell viability and expansion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ad29e2deb0b9d316dad682c5a6cf8a0
https://doi.org/10.17504/protocols.io.261geojwol47/v1
https://doi.org/10.17504/protocols.io.261geojwol47/v1
Autor:
Upasana Sunil Arvindam, Philippa Kennedy, Brianna Ettestad, Shee Kwan Phung, Peter Hinderlie, James Lim, Jeffrey S Miller, Martin Felices
Publikováno v:
The Journal of Immunology. 206:56.17-56.17
For Natural Killer (NK) cell-based immunotherapy to succeed against solid tumors, NK cells need to enter a highly immunosuppressive tumor microenvironment (TME) and retain functionality. The objective of this study is to evaluate how hypoxia exerts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3c793bcc61e19ada6eed7be1c1866a
https://doi.org/10.4049/jimmunol.206.supp.56.17
https://doi.org/10.4049/jimmunol.206.supp.56.17