Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Philippa J, Talmud"'
Autor:
Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess, Suthesh Sivapalaratnam, Vinicius Tragante, Erik P.A. van Iperen, Ariel Brautbar, David S. Carrell, David R. Crosslin, Gail P. Jarvik, Helena Kuivaniemi, Iftikhar J. Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Gerard Tromp, Jens Baumert, Karen J. Cruickshanks, Martin Farrall, Aroon D. Hingorani, G. K. Hovingh, Marcus E. Kleber, Barbara E. Klein, Ronald Klein, Wolfgang Koenig, Leslie A. Lange, Winfried Mӓrz, Kari E. North, N. Charlotte Onland-Moret, Alex P. Reiner, Philippa J. Talmud, Yvonne T. van der Schouw, James G. Wilson, Mika Kivimaki, Meena Kumari, Jason H. Moore, Fotios Drenos, Folkert W. Asselbergs, Brendan J. Keating, Marylyn D. Ritchie
Publikováno v:
BioData Mining, Vol 10, Iss 1, Pp 1-20 (2017)
Abstract Background The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipopro
Externí odkaz:
https://doaj.org/article/e425535da8ac4698843693a6461d84e0
Autor:
Sophie Valleix, Guglielmo Verona, Noémie Jourde-Chiche, Brigitte Nédelec, P. Patrizia Mangione, Frank Bridoux, Alain Mangé, Ahmet Dogan, Jean-Michel Goujon, Marie Lhomme, Carolane Dauteuille, Michèle Chabert, Riccardo Porcari, Christopher A. Waudby, Annalisa Relini, Philippa J. Talmud, Oleg Kovrov, Gunilla Olivecrona, Monica Stoppini, John Christodoulou, Philip N. Hawkins, Gilles Grateau, Marc Delpech, Anatol Kontush, Julian D. Gillmore, Athina D. Kalopissis, Vittorio Bellotti
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Decrease in Apolipoprotein C-III (ApoC-III) yields a cardioprotective lipoprotein profile. Here, Valleix et al.reveal a novel ApoC-III variant conferring low plasma ApoC-III concentration and cardioprotection despite renal insufficiency, and, unexpec
Externí odkaz:
https://doaj.org/article/20852c4360d64aac8c27c28e258ec648
Autor:
Amir Ravandi, S. Matthijs Boekholdt, Ziad Mallat, Philippa J. Talmud, John J.P. Kastelein, Nicholas J. Wareham, Elizabeth R. Miller, Joelle Benessiano, Alain Tedgui, Joseph L. Witztum, Kay-Tee Khaw, Sotirios Tsimikas
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 10, Pp 1829-1836 (2011)
Levels of IgG and IgM autoantibodies (AA) to malondialdehyde (MDA)-LDL and apoB-immune complexes (ICs) were measured in 748 cases and 1,723 controls in the EPIC-Norfolk cohort and their association to coronary artery disease (CAD) events determined.
Externí odkaz:
https://doaj.org/article/64bde971861a436fbec11283a2f39eda
Autor:
Ibrahim A Y Hamad, Yue Fei, Anastasia Z Kalea, Dan Yin, Andrew J P Smith, Jutta Palmen, Steve E Humphries, Philippa J Talmud, Ann P Walker
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122471 (2015)
MicroRNA 122 (miR-122) is highly expressed in the liver where it influences diverse biological processes and pathways, including hepatitis C virus replication and metabolism of iron and cholesterol. It is processed from a long non-coding primary tran
Externí odkaz:
https://doaj.org/article/e5b8623e62104b3c870bf244d6f8df0a
Autor:
Frank G. Schaap, Melchior C. Nierman, Jimmy F.P. Berbée, Hiroaki Hattori, Philippa J. Talmud, Stefan F.C. Vaessen, Patrick C.N. Rensen, Robert A.F.M. Chamuleau, Jan Albert Kuivenhoven, Albert K. Groen
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 10, Pp 2333-2339 (2006)
The relevance of apolipoprotein A-V (apoA-V) for human lipid homeostasis is underscored by genetic association studies and the identification of truncation-causing mutations in the APOA5 gene as a cause of type V hyperlipidemia, compatible with an LP
Externí odkaz:
https://doaj.org/article/71706867a91f493881928d7c88a9851d
Autor:
Stefan F.C. Vaessen, Frank G. Schaap, Jan-Albert Kuivenhoven, Albert K. Groen, Barbara A. Hutten, S. Matthijs Boekholdt, Hiroaki Hattori, Manjinder S. Sandhu, Sheila A. Bingham, Robert Luben, Jutta A. Palmen, Nicholas J. Wareham, Steve E. Humphries, John J.P. Kastelein, Philippa J. Talmud, Kay-Tee Khaw
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 9, Pp 2064-2070 (2006)
In mouse models, apolipoprotein A-V (apoA-V) exhibits triglyceride (TG)-lowering effects. We investigated the apoA-V/TG relationship and the association of apoA-V with coronary artery disease (CAD) risk by determining serum apoA-V levels and genotype
Externí odkaz:
https://doaj.org/article/a0e5475586a1437a92e5e45642dda8c1
Autor:
Wai-man R. Wong, Jeffrey W. Stephens, Jayshree Acharya, Steven J. Hurel, Steve E. Humphries, Philippa J. Talmud
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1565-1571 (2004)
Apolipoprotein A-IV (apoA-IV) has been postulated to be antiatherogenic. Transgenic APOA4/Apoe−/− mice are protected against atherosclerosis, with plasma apoA-IV displaying antioxidant activity in vitro. In humans, there is an inverse relationshi
Externí odkaz:
https://doaj.org/article/06450d5a618a4a578324fe4e0884cd54
Autor:
Philippa J. Talmud, Steve Martin, Marja-Riitta Taskinen, M. Heikki Frick, Markku S. Nieminen, Y. Antero Kesäniemi, Amos Pasternack, Steve E. Humphries, Mikko Syvänne
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 4, Pp 750-756 (2004)
Animal and human studies support a role for apolipoprotein A-V (apoA-V) in triglyceride (TG) metabolism. We examined the relationship of APOA5 −1131T>C and S19W with lipid subfractions and progression of atherosclerosis in the Lopid Coronary Angiog
Externí odkaz:
https://doaj.org/article/e4355aba2fd5494a85eb9709ed8447a2
Autor:
Syrah Khan, Anne-Marie Minihane, Philippa J. Talmud, John W. Wright, Margaret C. Murphy, Christine M. Williams, Bruce A. Griffin
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 979-985 (2002)
We sought to test the hypothesis that dietary long-chain n-3 PUFA (LC n-3 PUFA) in fish oil stimulate the gene expression of lipoprotein lipase (LPL) in human adipose tissue (AT). In a randomized, double blind, placebo-controlled, cross-over study, 5
Externí odkaz:
https://doaj.org/article/7ccce47a49f4415cb4a49998362b7c0a
Publikováno v:
F1000Research, Vol 2 (2014)
For the majority of organs in developing vertebrate embryos, left-right asymmetry is controlled by a ciliated region; the left-right organizer node in the mouse and human, and the Kuppfer’s vesicle in the zebrafish. In the zebrafish, laterality cue
Externí odkaz:
https://doaj.org/article/e8c954cfbc2747f18f560fa7948bd415