Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Philippa H. Francis-West"'
Autor:
Philippa H. Francis-West, S. Allen, Raj K. Ladher, Frank P. Luyten, A. Abdelfattah, Charles W. Archer, S. MacPherson, Ping Chen, J. Parish, C. Allen
Publikováno v:
Scopus-Elsevier
Mutations in GDF-5, a member of the TGF-β superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and Hunter-Thompson and Grebe-type chondrodysplasias in humans. These syndromes are all characterised by the shortening of the
Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control
Autor:
Delphine Duprez, Philippa H. Francis-West, Charles W. Archer, Paul M. Brickell, Esther Bell, Michael K. Richardson, Lewis Wolpert
Publikováno v:
Mechanisms of Development. 57:145-157
Bone morphogenetic proteins are members of the transforming growth factor beta (TGF beta) superfamily which are involved in a range of developmental processes including modelling of the skeleton. We show here that Bmp-2 is expressed in mesenchyme sur
Autor:
Concepción Rodriguez, Adrian P. Hardy, Lewis Wolpert, Juan-Carlos Izpisúa-Belmonte, Delphine Duprez, Philippa H. Francis-West, Michael K. Richardson
Publikováno v:
ResearcherID
The developing chick limb has two major signalling centres; the apical ectodermal ridge maintains expression of several important genes and outgrowth of the limb, and the polarising region specifies the pattern of skeletal elements along the anteropo
Publikováno v:
Developmental Dynamics. 201:168-178
Bone morphogenetic proteins BMP-4 and BMP-2 are closely-related members of the transforming growth factor-beta superfamily that have been implicated in signalling in a number of developmental systems. To determine whether they could be involved in th
Autor:
Delphine M. Duprez, Konstadina Kostakopoulou, Philippa H. Francis-West, Cheryll Tickle, Paul M. Brickell
Publikováno v:
Development (Cambridge, England). 122(6)
Bone morphogenetic protein-2 (BMP-2) has been implicated in the polarizing region signalling pathway, which specifies pattern across the antero-posterior of the developing vertebrate limb. Retinoic acid and Sonic Hedgehog (SHH) can act as polarizing
Autor:
Cheryll Tickle, C. Rodriguez, D.A. Ede, Paul M. Brickell, Philippa H. Francis-West, K. E. Robertson, David W. Burt, J. C. Izpisúa-Belmonte, C. Gribbin, B. Houston
Publikováno v:
ResearcherID
The chicken mutant talpid3 (ta3) has polydactylous limbs with up to 7-8 morphologically similar digits. This lack of antero-posterior polarity in digit pattern is correlated with symmetrical expression of genes of the HoxD complex. We determined the
Autor:
Lewis Wolpert, Philippa H. Francis-West, Charles W. Archer, A J Barlow, Paul M. Brickell, Esther Bell, Frank P. Luyten, Ping Chen, A Adelfattah, Michael K. Richardson
Publikováno v:
Annals of the New York Academy of Sciences. 785:254-255