Zobrazeno 1 - 2 of 2 pro vyhledávání: '"Philipp Terpe"'
1
Akademický článek
The synergism of cytosolic acidosis and reduced NAD+/NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis
Autor: Philipp Terpe, Stefanie Ruhs, Virginie Dubourg, Michael Bucher, Michael Gekle
Publikováno v: Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background During sepsis, serve vascular dysfunctions lead to life-threatening multiple organ failure, due to vascular smooth muscle cells (VSMC) impairments, resulting in vasoplegia, hypotension and hypoperfusion. In addition, septic patien
Externí odkaz: https://doaj.org/article/a2587d7e33174de885615510f343523c
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2
Akademický článek
Hypothesis-generating analysis of the impact of non-damaging metabolic acidosis on the transcriptome of different cell types: Integrated stress response (ISR) modulation as general transcriptomic reaction to non-respiratory acidic stress?
Autor: Virginie Dubourg, Marie-Christin Schulz, Philipp Terpe, Stefanie Ruhs, Michael Kopf, Michael Gekle
Publikováno v: PLoS ONE, Vol 18, Iss 8, p e0290373 (2023)
Extracellular pH is an important parameter influencing cell function and fate. Microenvironmental acidosis accompanies different pathological situations, including inflammation, hypoxia and ischemia. Research focussed mainly on acidification of the t
Externí odkaz: https://doaj.org/article/360195c8a1d14d38b2775731fb86792c
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