Výsledky vyhledávání - "Philipp T. Kühn"

Collagen morphology influences macrophage shape and marker expression in vitro

Autor: Shardul A. Bhusari, Gwenda F Vasse, Qihui Zhou, Patrick van Rijn, Catharina Reker-Smit, Barbro N. Melgert, Philipp T. Kühn

Publikováno v: Journal of Immunology and Regenerative Medicine, 1, 13-20

Fibrosis is a process in which an accumulation of extracellular matrix (ECM) leads to an impaired function of the affected organ. Pulmonary fibrosis is the end-stage of several lung diseases, characterized by scarring of the lungs. Although macrophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b35e25cf876fbd46eea3a61b66dd3f
https://hdl.handle.net/11370/8508ea9c-eb7c-44a0-b93c-f4a97764282c

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Screening Platform for Cell Contact Guidance Based on Inorganic Biomaterial Micro/nanotopographical Gradients

Autor: Qihui Zhou, Carlos F. Guimarães, Patrick van Rijn, Theo G. van Kooten, Olga E. Castañeda Ocampo, Philipp T. Kühn

Publikováno v: ACS Applied Materials & Interfaces, 9(37), 31433-31445. AMER CHEMICAL SOC
ACS Applied Materials & Interfaces

High -throughput screening (HTS) methods based on topography gradients or arrays have been extensively used to investigate cell material interactions. However, it is a huge technological challenge to cost efficiently prepare topographical gradients o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f64673a7d480753ee90800b2912262
https://hdl.handle.net/11370/dde0b952-e410-4f44-891f-cb3d0a440cae

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Influence of Polymer Architecture on the Electrochemical Deposition of Polyelectrolytes

Autor: Ulrich Simon, Olga Mergel, Philipp T. Kühn, Felix A. Plamper, Sabine Schneider

Publikováno v: Electrochimica Acta, 232, 98-105. PERGAMON-ELSEVIER SCIENCE LTD

This study demonstrates the effect of polymer topology and molar mass on the electrodeposition of preformed polyelectrolytes. The polyelectrolyte solubility is manipulated electrochemically using a counterion switching approach. Upon this, a triggere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df5ceef11f2b9bc1466e8ede38f4978
https://hdl.handle.net/11370/a30e2817-0dde-4ce5-acea-8252b7549ad7

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Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis

Autor: Tácia Tavares Aquinas Liguori, Patrick van Rijn, Philipp T. Kühn, Luiz Felipe P. Moreira, Gabriel Romero Liguori, Qihui Zhou, Guilherme Garcia Barros, Martin C. Harmsen

Publikováno v: Stem Cells International, Vol 2019 (2019)
Stem cells international, 2019:5387850. HINDAWI LTD
Stem Cells International

Introduction. Progenitor cells cultured on biomaterials with optimal physical-topographical properties respond with alignment and differentiation. Stromal cells from connective tissue can adversely differentiate to profibrotic myofibroblasts or favor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c702f1605e576fb3a864e5f9d17d4afe
https://doaj.org/article/7312687779474916b590730126656212

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Cargo shuttling by electrochemical switching of core-shell microgels obtained by a facile one-shot polymerization

Autor: Sebastian Schöttner, Patrick van Rijn, Michael Noyong, Tobias Caumanns, Rahul Tiwari, Markus Gallei, Felix A. Plamper, Dominik Wöll, Martinus de Kanter, Marc C. A. Stuart, Sabine Schneider, Christoph Janzen, Ulrich Simon, Joachim Mayer, Olga Mergel, Philipp T. Kühn, Damla Keskin

Publikováno v: Chemical science 10(6), 1844-1856 (2019). doi:10.1039/C8SC04369H
Chemical Science, 10(6), 1844-1856. ROYAL SOC CHEMISTRY

Chemical science (2018). doi:10.1039/C8SC04369H
Published by RSC, Cambridge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee8fbcd135877e430211dd427154dae

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Double Linear Gradient Biointerfaces for Determining Two-Parameter Dependent Stem Cell Behavior

Autor: Patrick van Rijn, Qihui Zhou, Aneta M. Schaap-Oziemlak, Torben A. B. van der Boon, Theo G. van Kooten, Philipp T. Kühn

Publikováno v: Chemnanomat, 2(5), 407-413. Wiley

Two-parameter contributions of stiffness and wettability display altered behavior of hBM-MSCs as compared to solely investigating the wettability of the biointerface with a homogenous stiffness. The importance of double parameter influence is identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94ba571e60c42e2c4fdb3af1e5ecf93
https://doi.org/10.1002/cnma.201600028

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Directed Autonomic Flow

Autor: Barbara Santos de Miranda, Philipp T. Kühn, Patrick van Rijn

Publikováno v: Abstracts of Papers of the American Chemical Society, 251. AMER CHEMICAL SOC
Advanced materials, 27(45), 7401-7406. WILEY-V C H VERLAG GMBH

Unidirectional coherent motion of a self-moving droplet is achieved and combined in a functional motility fluidic chip for chemical reactions via a novel and straightforward approach. The droplet shows both increased movement speeds and displacement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e2a5d087a7fdd7027e8ad6a44b3bab
https://doi.org/10.1002/adma.201503000

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Development of a Novel Orthogonal Double Gradient for High-Throughput Screening of Mesenchymal Stem Cells-Materials Interaction

Autor: Lu Ge, Qihui Zhou, Patrick van Rijn, Carlos F. Guimarães, Liangliang Yang, Philipp T. Kühn

Publikováno v: Advanced Materials Interfaces, 5(18):1800504. Wiley

Surface gradients provide a powerful platform to accelerate multiscale design by efficiently studying of material-cell interactions to ultimately enhance function of synthetic clinical biomaterials. Herein, a novel orthogonal double gradient is repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f871b4ce720718462d8d6c7631781580
https://doi.org/10.1002/admi.201800504

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Biomaterial–stem cell interactions and their impact on stem cell response

Autor: Philipp T. Kühn, Patrick van Rijn, Aneta M. Schaap-Oziemlak, Theo G. van Kooten

Publikováno v: RSC Adv.. 4:53307-53320

In this review, current research in the field of biomaterial properties for directing stem cells are discussed and placed in a critical perspective. Regenerative medicine, in which stem cells play a crucial role, has become an interdisciplinary field

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0010a9428c36ebdb73ebfb68148c66
https://doi.org/10.1039/c4ra07915a

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