Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Philipp Stroebel"'
Autor:
Lisa Knoll, Jacob Hamm, Philipp Stroebel, Todorovic Jovan, Robert Goetze, Shiv Singh, Elisabeth Hessmann, Volker Ellenrieder, Christoph Ammer-Herrmenau, Albrecht Neesse
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 53, Iss , Pp 101002- (2024)
Background: Pancreatic ductal adenocarcinoma (PDAC) poorly responds to antineoplastic agents. Discrepancies between preclinical success and clinical failure of compounds has been a continuous challenge and major obstacle in PDAC research. Aim: To inv
Externí odkaz:
https://doaj.org/article/8b727644519844318e28a28330fb7aa9
Autor:
Sebastian Schade, Ute Koenig, Ardian Mekolli, Jochen Gaedcke, Albrecht Neesse, Johanna Reinecke, Marius Brunner, Ali Seif Amir Hosseini, Julia Kitz, Philipp Stroebel, Joachim Lotz, Michael Ghadimi, Volker Ellenrieder, Alexander Koenig
Publikováno v:
Case Reports in Gastroenterology, Vol 16, Iss 1, Pp 80-88 (2022)
Gastric cancer (GC) represents one of the most fatal neoplasms in gastrointestinal oncology and affected patients can only hope for cure in limited disease. In a metastatic situation however, patients have a worse prognosis finally resulting in cance
Externí odkaz:
https://doaj.org/article/46b5a7f78d744bb6883a145d5f8e4475
Autor:
Alexander Koenig, Sebastian Krug, Daniela Mueller, Peter J Barth, Ute Koenig, Michael Scharf, Volker Ellenrieder, Patrick Michl, Roland Moll, Kia Homayunfar, Peter Herbert Kann, Philipp Stroebel, Thomas M Gress, Anja Rinke
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188876 (2017)
Chromogranin A (CgA) is a well-established marker for diagnosis and follow up of patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN). Recently, it has been shown that plasma levels of CgA correlate with tumor load and predict surv
Externí odkaz:
https://doaj.org/article/e45ef43ac89145d1b45bbdc42b5f5ce7
Autor:
Anja von Au, Matthaeus Vasel, Sabrina Kraft, Carla Sens, Norman Hackl, Alexander Marx, Philipp Stroebel, Jörg Hennenlotter, Tilman Todenhöfer, Arnulf Stenzl, Sarah Schott, Hans-Peter Sinn, Antoinette Wetterwald, Justo Lorenzo Bermejo, Marco G Cecchini, Inaam A Nakchbandi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 8, Pp 925-938 (2013)
Fibronectin is ubiquitously expressed in the extracellular matrix, and experimental evidence has shown that it modulates blood vessel formation. The relative contribution of local and circulating fibronectin to blood vessel formation in vivo remains
Externí odkaz:
https://doaj.org/article/1bd397fdc23c48fda9dccebf2d503938
Autor:
Maria Schubert, Martin Spahn, Susanne Kneitz, Claus Jürgen Scholz, Steven Joniau, Philipp Stroebel, Hubertus Riedmiller, Burkhard Kneitz
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65064 (2013)
BACKGROUND: The identification of additional prognostic markers to improve risk stratification and to avoid overtreatment is one of the most urgent clinical needs in prostate cancer (PCa). MicroRNAs, being important regulators of gene expression, are
Externí odkaz:
https://doaj.org/article/1d12e7b8540844d390f3d556a5f51efd
Autor:
Emre Taylan Duman, Maren Sitte, Karly Conrads, Adi Mackay, Fabian Ludewig, Philipp Stroebel, Volker Ellenrieder, Elisabeth Hessmann, Argyris Papantonis, Gabriela Salinas
Most clinical diagnostic and genomic research setups focus almost exclusively on coding regions and essential splice sites, thereby overlooking other non-coding variants. As a result, intronic variants that can promote mis-splicing events across a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6eb608b546ee737ae14d7f992ef4bd
https://doi.org/10.1101/2023.05.08.539836
https://doi.org/10.1101/2023.05.08.539836
Autor:
Sebastian Wolf, Constanze Schneider, Roland Schmitz, Kwang Seok Lee, Mikolaj Slabicki, Hans Christian Reinhardt, Henning Urlaub, Craig J. Thomas, Anne C. Wilke, Hubert Serve, Fernando Kreuz, Joshua D. Rabinowitz, Dominique Jahn, Michele Ceribelli, Christian Brandts, Kimberly Stegmaier, Matthew G. Vander Heiden, Caroline A. Lewis, Thomas Oellerich, Kamil Bojarczuk, Thorsten Zenz, Daniel J. Hodson, Sara A Rieke, Yana Pikman, James Q Wang, Xincheng Xu, Michael Engelke, Hahn Kim, Hanibal Bohnenberger, Zana A. Coulibaly, Clemens A Schmitt, Federico Comoglio, James D. Phelan, Louis M. Staudt, Carmen Doebele, Sebastian Scheich, Björn Chapuy, Frank Schnuetgen, Gero Knittel, Frances A. Tosto, Philipp Stroebel, Alena Zindel, Björn Häupl, Philipp Stauder, Thanh Hung Dang
Publikováno v:
Blood
Burkitt lymphoma (BL) is an aggressive lymphoma type that is currently treated by intensive chemoimmunotherapy. Despite the favorable clinical outcome for most patients with BL, chemotherapy-related toxicity and disease relapse remain major clinical
Autor:
Georg Emons, Noam Auslander, Peter Jo, Julia Kitz, Azadeh Azizian, Yue Hu, Clemens F. Hess, Claus Roedel, Ulrich Sax, Gabriela Salinas, Philipp Stroebel, Frank Kramer, Tim Beissbarth, Marian Grade, Michael Ghadimi, Eytan Ruppin, Thomas Ried, Jochen Gaedcke
Publikováno v:
British journal of cancer. 127(4)
Purpose Preoperative (neoadjuvant) chemoradiotherapy (CRT) and total mesorectal excision is the standard treatment for rectal cancer patients (UICC stage II/III). Up to one-third of patients treated with CRT achieve a pathological complete response (
Autor:
Alina Pflaume, Samantha Exner, Katja Herrera-Glomm, Jürgen Loskutov, Ulrike Pfohl, Manuela Regenbrecht, Sushmitha Sankarasubramanian, Lena Wedeken, Sabine Finkler, Larissa Ruhe, Quirin Graf Adelmann, Christoph Reinhard, Philipp Stroebel, Christian R. Regenbrecht
Publikováno v:
Cancer Research. 82:6223-6223
Patient-derived 3D cell culture models (PD3D®) developed as a powerful tool for disease modelling, biomarker and drug discovery. Currently, they are gaining increasing significance in the field of personalized oncology, as they recapitulate the hist
Autor:
Muhammad Umair Latif, Geske Elisabeth Schmidt, Sercan Mercan, Raza Rahman, Christine Silvia Gibhardt, Ioana Stejerean-Todoran, Kristina Reutlinger, Elisabeth Hessmann, Shiv K Singh, Abdul Moeed, Abdul Rehman, Umer Javed Butt, Hanibal Bohnenberger, Philipp Stroebel, Sebastian Christopher Bremer, Albrecht Neesse, Ivan Bogeski, Volker Ellenrieder
Publikováno v:
Gut. 71(12)
ObjectivesNon-alcoholic fatty liver disease (NAFLD) can persist in the stage of simple hepatic steatosis or progress to steatohepatitis (NASH) with an increased risk for cirrhosis and cancer. We examined the mechanisms controlling the progression to