Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Philipp Schineis"'
Autor:
Elena C Sigmund, Lilian Baur, Philipp Schineis, Jorge Arasa, Victor Collado-Diaz, Martina Vranova, Rolf A K Stahl, Marcus Thelen, Cornelia Halin
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249068 (2021)
Atypical chemokine receptor ACKR3 (formerly CXCR7) is a scavenging receptor that has recently been implicated in murine lymphatic development. Specifically, ACKR3-deficiency was shown to result in lymphatic hyperplasia and lymphedema, in addition to
Externí odkaz:
https://doaj.org/article/00cb1bafafed433f9389a983fb5f9f10
Autor:
Ann-Helen Willrodt, Ann-Charlott Salabarria, Philipp Schineis, Desislava Ignatova, Morgan Campbell Hunter, Martina Vranova, Alexandra M. Golding-Ochsenbein, Elena Sigmund, Annatina Romagna, Verena Strassberger, Marina Fabbi, Silvano Ferrini, Claus Cursiefen, Dario Neri, Emmanuella Guenova, Felix Bock, Cornelia Halin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Activated leukocyte cell adhesion molecule (ALCAM, CD166) is a cell adhesion molecule of the immunoglobulin superfamily and has been implicated in diverse pathophysiological processes including T cell activation, leukocyte trafficking, and (lymph)ang
Externí odkaz:
https://doaj.org/article/363dd34553d042b691dc078098488e14
Autor:
Mona C. Friess, Ioannis Kritikos, Philipp Schineis, Jessica Danielly Medina-Sanchez, Anastasia-Olga Gkountidi, Angela Vallone, Elena C. Sigmund, Corina Schwitter, Martina Vranova, Christoph Matti, Jorge Arasa, Cansaran Saygili Demir, Esther Bovay, Steven T. Proulx, Michio Tomura, Antal Rot, Daniel F. Legler, Tatiana V. Petrova, Cornelia Halin
Publikováno v:
Cell Reports, 38 (5)
Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334
Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334
T cell migration via afferent lymphatics to draining lymph nodes (dLNs) depends on expression of CCR7 in T cells and CCL21 in the lymphatic vasculature. Once T cells have entered lymphatic capillaries, they slowly migrate into contracting collecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51c1dcb4ca476e8a49312f08b854f8f
Autor:
Philipp Schineis, Sarah Vogel-Kindgen, Martine Theisen, Zuzanna K. Kotkowska, Pål Johansen, Saurav Subedi, Mona C. Friess, Isabel Kolm, Ying Waeckerle-Men, Thomas M. Kündig, David Schwyter, Eleni Maria Varypataki, Anders Høgset, Lucy Hausammann, Bruno Gander, Cornelia Halin
Antigen cross-presentation to cytotoxic CD8+ T cells is crucial for the induction of anti-tumor and anti-viral immune responses. Recently, co-encapsulation of photosensitizers and antigens into microspheres and subsequent photochemical internalizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2685436b07fa5daf767fe0f63276e72e
https://www.zora.uzh.ch/id/eprint/209624/
https://www.zora.uzh.ch/id/eprint/209624/
Publikováno v:
Angewandte Chemie. 131:7212-7216
Autor:
Mona C. Friess, Cornelia Halin, Morgan Campbell Hunter, Philipp Schineis, Jorge Arasa, Carlotta Tacconi, Neil Paterson, Michael Detmar, Victor Collado-Diaz, Tim Lämmermann, Friedemann Kiefer, Takashi Nagasawa, Taija Makinen, Markus Moser, Ioannis Kritikos, Jessica Danielly Medina-Sanchez, Elena C. Sigmund
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, 218 (7)
Journal of Experimental Medicine
Journal of Experimental Medicine, 218 (7)
Journal of Experimental Medicine
Dendritic cells (DCs) are thought to enter afferent lymphatics exclusively through lymphatic capillaries. This study reveals that in inflammation, DCs additionally enter downstream of capillaries into contracting collectors, allowing for a more rapid
Autor:
Silvana Geisshüsler, Philipp Schineis, Lara Langer, Ying Wäckerle-Men, Jean-Christophe Leroux, Cornelia Halin, Sarah Vogel-Kindgen, Pål Johansen, Bruno Gander
Publikováno v:
Advanced NanoBiomed Research, 2 (4)
Particulate antigen-delivery systems are instrumental for therapeutic vaccination, aiming at improving the safety and efficacy of treatments by targeting specialized antigen-presenting cells (APCs). However, the induction of potent adaptive immune re
Autor:
Rolf A.K. Stahl, Cornelia Halin, Philipp Schineis, Lilian Baur, Elena C. Sigmund, Jorge Arasa, Victor Collado-Diaz, Martina Vranova, Marcus Thelen
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249068 (2021)
PLoS ONE
PLoS ONE, 16 (4)
PLoS ONE
PLoS ONE, 16 (4)
Atypical chemokine receptor ACKR3 (formerly CXCR7) is a scavenging receptor that has recently been implicated in murine lymphatic development. Specifically, ACKR3-deficiency was shown to result in lymphatic hyperplasia and lymphedema, in addition to
Publikováno v:
Angewandte Chemie. International Edition, 58 (21)
Short linear peptides can overcome certain limitations of small molecules for targeting protein-protein interactions (PPIs). Herein, the interaction between the human chemokine CCL19 with chemokine receptor CCR7 was investigated to obtain receptor-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415dc7a52e390dfca67bf7740f98f148
https://hdl.handle.net/20.500.11850/344024
https://hdl.handle.net/20.500.11850/344024
Autor:
Ann-Helen, Willrodt, Ann-Charlott, Salabarria, Philipp, Schineis, Desislava, Ignatova, Morgan Campbell, Hunter, Martina, Vranova, Alexandra M, Golding-Ochsenbein, Elena, Sigmund, Annatina, Romagna, Verena, Strassberger, Marina, Fabbi, Silvano, Ferrini, Claus, Cursiefen, Dario, Neri, Emmanuella, Guenova, Felix, Bock, Cornelia, Halin
Publikováno v:
Frontiers in Immunology
Activated leukocyte cell adhesion molecule (ALCAM, CD166) is a cell adhesion molecule of the immunoglobulin superfamily and has been implicated in diverse pathophysiological processes including T cell activation, leukocyte trafficking, and (lymph)ang