Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Philipp Schick"'
Autor:
Vanessa Domsta, Tessa Boralewski, Martin Ulbricht, Philipp Schick, Julius Krause, Anne Seidlitz
Publikováno v:
International Journal of Pharmaceutics: X, Vol 8, Iss , Pp 100263- (2024)
Hot-melt extrusion (HME) potentially coupled with 3D printing is a promising technique for the manufacturing of dosage forms such as drug-eluting implants which might even be individually adapted to patient-specific anatomy. However, these manufactur
Externí odkaz:
https://doaj.org/article/38eac8f9968b43e7a427b672c7a615b3
Autor:
Theodora Tzakri, Lara Rehenbrock, Stefan Senekowitsch, Adrian Rump, Philipp Schick, Julius Krause, Marie-Luise Kromrey, Michael Grimm, Werner Weitschies
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2584 (2023)
Because of the importance of gastric emptying for pharmacokinetics, numerous methods have been developed for its determination. One of the methods is the salivary tracer technique, which utilizes an ice capsule containing caffeine as a salivary trace
Externí odkaz:
https://doaj.org/article/43bcb0d5ba9749b5b2b8d3aaef41c1ea
Autor:
Dariah-Sohreh Seradj, Regine Beeck, Annika Haase, Julius Krause, Philipp Schick, Werner Weitschies
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1128 (2023)
The microbiome of the colon is characterized by its great diversity. This varies not only intra- but also interindividually and is influenced by endogenous and exogenous factors, such as dietary and lifestyle factors. The aim of this work was to inve
Externí odkaz:
https://doaj.org/article/3c8e6386dd9647209ec07db6e4e8123c
Autor:
Stefan Senekowitsch, Constantin Foja, Toni Wildgrube, Philipp Schick, Christoph Rosenbaum, Julius Krause, Friederike Brokmann, Marie-Luise Kromrey, Stefan Engeli, Werner Weitschies, Michael Grimm
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 1012 (2023)
Sparkling water is said to increase gastric motility by the release of carbon dioxide, thereby potentially affecting the pharmacokinetics of orally administered drugs. The hypothesis of the present work was that the induction of gastric motility by i
Externí odkaz:
https://doaj.org/article/887d30c860634476959f048009cf7185
Autor:
Regine Beeck, Annemarie Dols, Felix Schneider, Dariah-Sohreh Seradj, Julius Krause, Philipp Schick, Werner Weitschies
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1049 (2022)
In recent years, the colon has become a hot topic in biopharmaceutical research as several in vitro models of the human colon have been presented. A major focus is on the characterization of the microbiota and its capabilities. The aim of the present
Externí odkaz:
https://doaj.org/article/dcf1aba2d638418ea9fda8379c61556c
Autor:
Stefan Senekowitsch, Philipp Schick, Bertil Abrahamsson, Patrick Augustijns, Thomas Gießmann, Hans Lennernäs, Christophe Matthys, Luca Marciani, Xavier Pepin, Alan Perkins, Maximilian Feldmüller, Sarah Sulaiman, Werner Weitschies, Clive G. Wilson, Maura Corsetti, Mirko Koziolek
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 801 (2022)
Drug absorption following oral administration is determined by complex and dynamic interactions between gastrointestinal (GI) physiology, the drug, and its formulation. Since many of these interactions are not fully understood, the COST action on “
Externí odkaz:
https://doaj.org/article/066006c0c1c1439380a8f6bc23b79db6
Publikováno v:
Molecular pharmaceutics.
Delayed gastric emptying is known to have a major impact on drug absorption. While the test meal recommended by the FDA and EMA to study food effects represents a worst-case scenario, it does not reflect the reality of the patients. Physiologically b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcb91752c892be79db06a9e7c4fbdc8
https://pubmed.ncbi.nlm.nih.gov/36548544
https://pubmed.ncbi.nlm.nih.gov/36548544
Autor:
Werner Siegmund, Franziska Schindele, Philipp Schick, Mirko Koziolek, Werner Weitschies, Felix Schneider, Taddese Mekonnen Ambay, Rainer Haas, Maximilian Sager, Michael Grimm
Publikováno v:
Journal of Pharmaceutical Sciences. 110:1302-1309
Infections with Helicobacter pylori are a global challenge. Currently, H. pylori infections are treated systemically, but the eradication rates of the different therapy regimens are declining due to the growing number of bacterial strains resistant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a45cc73338e41d00c2ce85b69e74dd
https://doi.org/10.1016/j.xphs.2020.11.021
https://doi.org/10.1016/j.xphs.2020.11.021
Autor:
Stefan Senekowitsch, Eliza Wietkamp, Michael Grimm, Franziska Schmelter, Philipp Schick, Anna Kordowski, Christian Sina, Hans Otzen, Werner Weitschies, Martin Smollich
Publikováno v:
Nutrients; Volume 15; Issue 8; Pages: 1852
(1) Background: Spermidine is a biogenic polyamine that plays a crucial role in mammalian metabolism. As spermidine levels decline with age, spermidine supplementation is suggested to prevent or delay age-related diseases. However, valid pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6caccf20c4dcf2f64f491914270a8722
https://doi.org/10.3390/nu15081852
https://doi.org/10.3390/nu15081852
Autor:
Clive G. Wilson, Leon Aarons, Patrick Augustijns, Joachim Brouwers, Adam S. Darwich, Tom De Waal, Grzegorz Garbacz, Simone Hansmann, Dagmara Hoc, Anela Ivanova, Mirko Koziolek, Christos Reppas, Philipp Schick, Maria Vertzoni, J. Arturo García-Horsman
Publikováno v:
Aarons, L 2021, ' Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective ', European Journal of Pharmaceutical Sciences . https://doi.org/10.1016/j.ejps.2021.106100
Funding Information: AI acknowledges the support of projects icp009 (ALKOOL) of PRACE-ICEI (grant agreement 800858) for awarding access to Piz Daint, at the Swiss National Supercomputing Centre (CSCS), Switzerland and BG05M2OP001–1.001–0004 (UNIT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2539f9583e36cc3176667f2192d6135f
https://doi.org/10.1016/j.ejps.2021.106100
https://doi.org/10.1016/j.ejps.2021.106100
