Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Philipp Schätzle"'
The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis
Autor:
Muriel Elhai, Raphael Micheroli, Miranda Houtman, Masoumeh Mirrahimi, Larissa Moser, Chantal Pauli, Kristina Bürki, Andrea Laimbacher, Gabriela Kania, Kerstin Klein, Philipp Schätzle, Mojca Frank Bertoncelj, Sam G. Edalat, Leandra Keusch, Alexandra Khmelevskaya, Melpomeni Toitou, Celina Geiss, Thomas Rauer, Maria Sakkou, George Kollias, Marietta Armaka, Oliver Distler, Caroline Ospelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Although patients with rheumatoid arthritis (RA) typically exhibit symmetrical joint involvement, some patients develop alternative disease patterns in response to treatment, suggesting that different molecular mechanism may underlie disease
Externí odkaz:
https://doaj.org/article/69a704ad8e714379b5b6e4a46b31ca7a
Autor:
Olga I. Kahn, Philipp Schätzle, Dieudonnée van de Willige, Roderick P. Tas, Feline W. Lindhout, Sybren Portegies, Lukas C. Kapitein, Casper C. Hoogenraad
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Microtubules in dendrites are characterized by mixed polarity orientation. Here, the authors show a role for adenomatous polyposis coli 2 (APC2) in regulating dendrite microtubule dynamics and dendrite development.
Externí odkaz:
https://doaj.org/article/ade6f2219360485a9d71326ab47cd9a9
Autor:
Marta Esteves da Silva, Max Adrian, Philipp Schätzle, Joanna Lipka, Takuya Watanabe, Sukhee Cho, Kensuke Futai, Corette J. Wierenga, Lukas C. Kapitein, Casper C. Hoogenraad
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 933-943 (2015)
Lateral diffusion in the membrane and endosomal trafficking both contribute to the addition and removal of AMPA receptors (AMPARs) at postsynaptic sites. However, the spatial coordination between these mechanisms has remained unclear, because little
Externí odkaz:
https://doaj.org/article/21093b42932a4bf1ba9c08b93abda438
Autor:
Martin Steuble, Tu-My Diep, Philipp Schätzle, Alexander Ludwig, Mitsuo Tagaya, Beat Kunz, Peter Sonderegger
Publikováno v:
Biology Open, Vol 1, Iss 8, Pp 761-774 (2012)
Summary Endocytosis of amyloid-β precursor protein (APP) is thought to represent the major source of substrate for the production of the amyloidogenic Aβ peptide by the β-secretase BACE1. The irreversible nature of proteolytic cleavage implies the
Externí odkaz:
https://doaj.org/article/0d6f6491a8aa47e5a7e382d68d207390
Autor:
Muriel elhai, Raphael Micheroli, Miranda Houtman, Masoumeh Mirrahimi, Larissa Moser, Chantal Pauli, Kristina Bürki, Andrea Laimbacher, Gabriela Kania, Kerstin Klein, Philipp Schätzle, Mojca Frank Bertoncelj, Sam Edalat, Maria Sakkou, George Kollias, Marietta Armaka, Oliver Distler, Caroline Ospelt
Most forms of arthritis, have a distinctive topographical pattern of joint involvement. Beyond these differences among diseases, there are also differences in phenotype and response to treatment between joints of the same type of arthritis, suggestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d294b60e59970be0c64c4d29ccc2df69
https://doi.org/10.21203/rs.3.rs-2543547/v1
https://doi.org/10.21203/rs.3.rs-2543547/v1
Autor:
Pasterkamp Rj, Maarten Altelaar, Philipp Schätzle, Casper C. Hoogenraad, Suzy Varderidou-Minasian
SUMMARYNeuronal development is a multistep process with different regulatory programs that shapes neurons to form dendrites, axons and synapses. To date, knowledge on neuronal development is largely based on murine data and largely restricted to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1f7a47430866b81b9ad7206cc5fc3a
https://doi.org/10.1101/599415
https://doi.org/10.1101/599415
Autor:
Anja Konietzny, Jeffrey Lopez-Rojas, Julia Bär, Michael R. Kreutz, Oliver Stork, Bas van Bommel, Marina Mikhaylova, Egor Y. Loktionov, Syed Ahsan Raza, Casper C. Hoogenraad, Pasham Parameshwar Reddy, Oliver Kobler, Rajeev Raman, Philipp Schätzle, Johannes Hradsky, Christina Spilker, PingAn Yuanxiang
Publikováno v:
Neuron, 97(5), 1110. Cell Press
Neuron
Neuron
Compartmentalization of calcium-dependent plasticity allows for rapid actin remodeling in dendritic spines. However, molecular mechanisms for the spatio-temporal regulation of filamentous actin (F-actin) dynamics by spinous Ca2+-transients are still
Publikováno v:
Methods in cell biology. 131
The microtubule (MT) cytoskeleton plays an active role during different phases of neuronal development and is an essential structure for stable neuronal morphology. MTs determine axon formation, control polarized cargo trafficking, and regulate the d
The microtubule (MT) cytoskeleton plays an active role during different phases of neuronal development and is an essential structure for stable neuronal morphology. MTs determine axon formation, control polarized cargo trafficking, and regulate the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::808aaa3a69224f99ea6ac22970f5726a
https://doi.org/10.1016/bs.mcb.2015.06.006
https://doi.org/10.1016/bs.mcb.2015.06.006
Autor:
Beat Kunz, Mitsuo Tagaya, Alexander Ludwig, Tu-My Diep, Martin Steuble, Peter Sonderegger, Philipp Schätzle
Publikováno v:
Biol Open
Biology Open
Biology Open, Vol 1, Iss 8, Pp 761-774 (2012)
Biology Open
Biology Open, Vol 1, Iss 8, Pp 761-774 (2012)
Summary Endocytosis of amyloid-β precursor protein (APP) is thought to represent the major source of substrate for the production of the amyloidogenic Aβ peptide by the β-secretase BACE1. The irreversible nature of proteolytic cleavage implies the