Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Philipp Rabe"'
Autor:
Philipp Rabe, Mareike Gehmlich, Anna Peters, Petra Krumbholz, Anders Nordström, Claudia Stäubert
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background The adaptation of cellular metabolism is considered a hallmark of cancer. Oncogenic signaling pathways support tumorigenesis and cancer progression through the induction of certain metabolic phenotypes associated with altered regu
Externí odkaz:
https://doaj.org/article/058940dd5e354755b4224de52ea5820b
Autor:
Anna Peters, Philipp Rabe, Petra Krumbholz, Hermann Kalwa, Robert Kraft, Torsten Schöneberg, Claudia Stäubert
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Medium-chain fatty acids and their 3-hydroxy derivatives are metabolites endogenously produced in humans, food-derived or originating from bacteria. They activate G protein-coupled receptors, including GPR84 and HCA3, which regula
Externí odkaz:
https://doaj.org/article/852a76c2e2d146cb9a096ee57dcd02f3
Publikováno v:
Cancer Letters. 526:91-102
Cancer cells display metabolic alterations to meet the bioenergetic demands for their high proliferation rates. Succinate is a central metabolite of the tricarboxylic acid (TCA) cycle, but was also shown to act as an oncometabolite and to specificall
Autor:
Sascha Heinitz, Michael Traurig, Jonathan Krakoff, Philipp Rabe, Claudia Stäubert, Michael Stumvoll, Matthias Blüher, Leslie Baier, Paolo Piaggi
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Anna Peters, Philipp Rabe, Aenne-Dorothea Liebing, Petra Krumbholz, Anders Nordström, Elisabeth Jäger, Robert Kraft, Claudia Stäubert
Publikováno v:
Pharmacological research. 176
G protein-coupled receptors (GPCRs) are key regulatory proteins of immune cell function inducing signaling in response to extracellular (pathogenic) stimuli. Although unrelated, hydroxycarboxylic acid receptor 3 (HCA3) and GPR84 share signaling via G