Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Philipp O Tsvetkov"'
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178933 (2017)
Abundant regulatory 14-3-3 proteins have an extremely wide interactome and coordinate multiple cellular events via interaction with specifically phosphorylated partner proteins. Notwithstanding the key role of 14-3-3/phosphotarget interactions in man
Externí odkaz:
https://doaj.org/article/6fdbf4b1037348cd908c523527a3c6c4
Autor:
Irina Yu Petrushanko, Vladimir M Lobachev, Alexey S Kononikhin, Alexander A Makarov, Francois Devred, Hervé Kovacic, Aslan A Kubatiev, Philipp O Tsvetkov
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158726 (2016)
NOX5 protein, one of the most active generators of reactive oxygen species (ROS), plays an important role in many processes, including regulation of cell growth, death and differentiation. Because of its central role in ROS generation, it needs to be
Externí odkaz:
https://doaj.org/article/56f4ab44727242238ee5b58463f2109a
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128704 (2015)
Cell biology and crystallographic studies have suggested a functional link between stathmin and microtubule targeting agents (MTAs). In a previous study we showed that stathmin increases vinblastine (VLB) binding to tubulin, and that conversely VLB i
Externí odkaz:
https://doaj.org/article/1d146a9fedff45c48536a69b3a3e2610
Autor:
Dmitry Kaluzhny, Nikolay Ilyinsky, Andrei Shchekotikhin, Yuri Sinkevich, Philipp O Tsvetkov, Vladimir Tsvetkov, Alexander Veselovsky, Mikhail Livshits, Olga Borisova, Alexander Shtil, Anna Shchyolkina
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27151 (2011)
Linear heteroareneanthracenediones have been shown to interfere with DNA functions, thereby causing death of human tumor cells and their drug resistant counterparts. Here we report the interaction of our novel antiproliferative agent 4,11-bis[(2-{[ac
Externí odkaz:
https://doaj.org/article/1c7cfb789ad84d7dae1107341c325890
Autor:
María Cecilia González García, Caroline Radix, Claude Villard, Gilles Breuzard, Pascal Mansuelle, Pascale Barbier, Philipp O. Tsvetkov, Harold De Pomyers, Didier Gigmes, François Devred, Hervé Kovacic, Kamel Mabrouk, José Luis
Publikováno v:
Molecules, Vol 27, Iss 23, p 8241 (2022)
Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen severa
Externí odkaz:
https://doaj.org/article/5bea319f2fbc48778fcfb4e4890aebd3
Autor:
Viktoriia E. Baksheeva, Philipp O. Tsvetkov, Arthur O. Zalevsky, Vasiliy I. Vladimirov, Neonila V. Gorokhovets, Dmitry V. Zinchenko, Sergei E. Permyakov, François Devred, Evgeni Yu. Zernii
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 956 (2022)
Neuronal calcium sensors (NCSs) are the family of EF-hand proteins mediating Ca2+-dependent signaling pathways in healthy neurons and neurodegenerative diseases. It was hypothesized that the calcium sensor activity of NCSs can be complemented by sens
Externí odkaz:
https://doaj.org/article/07850d9bb9fe4557b9f876af4180b0ed
Autor:
Viktoriia E. Baksheeva, Andrei Yu. Roman, Claude Villard, François Devred, Deborah Byrne, Dahbia Yatoui, Arthur O. Zalevsky, Alisa A. Vologzhannikova, Andrey S. Sokolov, Sergei E. Permyakov, Andrey V. Golovin, Gary S. Shaw, Philipp O. Tsvetkov, Evgeni Yu. Zernii
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1823 (2021)
S100A1 is a member of the S100 family of small ubiquitous Ca2+-binding proteins, which participates in the regulation of cell differentiation, motility, and survival. It exists as homo- or heterodimers. S100A1 has also been shown to bind Zn2+, but th
Externí odkaz:
https://doaj.org/article/3e119f9307df406d953f6da5bad864a5
Autor:
Cyrille Garnier, François Devred, Deborah Byrne, Rémy Puppo, Andrei Yu. Roman, Soazig Malesinski, Andrey V. Golovin, Régine Lebrun, Natalia N. Ninkina, Philipp O. Tsvetkov
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Aggregation of TDP-43 (transactive response DNA binding protein 43 kDa) is a hallmark of certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Moreover, intracellular TDP-43-positive inclusions ar
Externí odkaz:
https://doaj.org/article/2c0c8563f1e940049ce56f22e73b5816
Autor:
Pascale Barbier, François Devred, Françoise Guerlesquin, Diane Allegro, Malesinski Soazig, Romain La Rocca, Andrey V. Golovin, Philipp O. Tsvetkov
Publikováno v:
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2022, 209, pp.779-784. ⟨10.1016/j.ijbiomac.2022.04.058⟩
International Journal of Biological Macromolecules, 2022, 209, pp.779-784. ⟨10.1016/j.ijbiomac.2022.04.058⟩
Tau protein has been extensively studied due to its key roles in microtubular cytoskeleton regulation and in the formation of aggregates found in some neurodegenerative diseases. Recently it has been shown that zinc is able to induce tau aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f1c69c5ebcbf5e614a26386e997515
https://doi.org/10.1016/j.ijbiomac.2022.04.058
https://doi.org/10.1016/j.ijbiomac.2022.04.058
Autor:
Viktoriia E. Baksheeva, Veronika V. Tiulina, Elena N. Iomdina, Sergey Yu. Petrov, Olga M. Filippova, Nina Yu. Kushnarevich, Elena A. Suleiman, Rémi Eyraud, François Devred, Marina V. Serebryakova, Natalia G. Shebardina, Dmitry V. Chistyakov, Ivan I. Senin, Vladimir A. Mitkevich, Philipp O. Tsvetkov, Evgeni Yu. Zernii
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2023, 24 (7132), ⟨10.3390/ijms24087132⟩
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7132
International Journal of Molecular Sciences, 2023, 24 (7132), ⟨10.3390/ijms24087132⟩
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7132
International audience; Primary open-angle glaucoma (POAG) is a frequent blindness-causing neurodegenerative disorder characterized by optic nerve and retinal ganglion cell damage most commonly due to a chronic increase in intraocular pressure. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e660e2000867dc9fd73c854a1bdcb7
https://hal-amu.archives-ouvertes.fr/hal-04066064
https://hal-amu.archives-ouvertes.fr/hal-04066064
