Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Philipp O Tsvetkov"'
Autor:
María Cecilia González García, Caroline Radix, Claude Villard, Gilles Breuzard, Pascal Mansuelle, Pascale Barbier, Philipp O. Tsvetkov, Harold De Pomyers, Didier Gigmes, François Devred, Hervé Kovacic, Kamel Mabrouk, José Luis
Publikováno v:
Molecules, Vol 27, Iss 23, p 8241 (2022)
Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen severa
Externí odkaz:
https://doaj.org/article/5bea319f2fbc48778fcfb4e4890aebd3
Autor:
Yann Fichou, Youssra K. Al-Hilaly, François Devred, Caroline Smet-Nocca, Philipp O. Tsvetkov, Joke Verelst, Joris Winderickx, Nick Geukens, Eugeen Vanmechelen, Audrey Perrotin, Louise Serpell, Bernard J Hanseeuw, Miguel Medina, Luc Buée, Isabelle Landrieu
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Insights into tau molecular structures have advanced significantly in recent years. This field has been the subject of recent breakthroughs, including the first cryo-electron microscopy structures of tau filaments from Alzheimer’s and Pick
Externí odkaz:
https://doaj.org/article/bb3797785c9b48ec921123c85a95810a
Autor:
Viktoriia E. Baksheeva, Philipp O. Tsvetkov, Arthur O. Zalevsky, Vasiliy I. Vladimirov, Neonila V. Gorokhovets, Dmitry V. Zinchenko, Sergei E. Permyakov, François Devred, Evgeni Yu. Zernii
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 956 (2022)
Neuronal calcium sensors (NCSs) are the family of EF-hand proteins mediating Ca2+-dependent signaling pathways in healthy neurons and neurodegenerative diseases. It was hypothesized that the calcium sensor activity of NCSs can be complemented by sens
Externí odkaz:
https://doaj.org/article/07850d9bb9fe4557b9f876af4180b0ed
Autor:
Viktoriia E. Baksheeva, Andrei Yu. Roman, Claude Villard, François Devred, Deborah Byrne, Dahbia Yatoui, Arthur O. Zalevsky, Alisa A. Vologzhannikova, Andrey S. Sokolov, Sergei E. Permyakov, Andrey V. Golovin, Gary S. Shaw, Philipp O. Tsvetkov, Evgeni Yu. Zernii
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1823 (2021)
S100A1 is a member of the S100 family of small ubiquitous Ca2+-binding proteins, which participates in the regulation of cell differentiation, motility, and survival. It exists as homo- or heterodimers. S100A1 has also been shown to bind Zn2+, but th
Externí odkaz:
https://doaj.org/article/3e119f9307df406d953f6da5bad864a5
Autor:
Cyrille Garnier, François Devred, Deborah Byrne, Rémy Puppo, Andrei Yu. Roman, Soazig Malesinski, Andrey V. Golovin, Régine Lebrun, Natalia N. Ninkina, Philipp O. Tsvetkov
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Aggregation of TDP-43 (transactive response DNA binding protein 43 kDa) is a hallmark of certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Moreover, intracellular TDP-43-positive inclusions ar
Externí odkaz:
https://doaj.org/article/2c0c8563f1e940049ce56f22e73b5816
Autor:
Pascale Barbier, Orgeta Zejneli, Marlène Martinho, Alessia Lasorsa, Valérie Belle, Caroline Smet-Nocca, Philipp O. Tsvetkov, François Devred, Isabelle Landrieu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Microtubules (MTs) play a fundamental role in many vital processes such as cell division and neuronal activity. They are key structural and functional elements in axons, supporting neurite differentiation and growth, as well as transporting motor pro
Externí odkaz:
https://doaj.org/article/30a70794bf7a4332ba3891d913a27264
Autor:
Philipp O. Tsvetkov, Andrei Yu. Roman, Viktoriia E. Baksheeva, Aliya A. Nazipova, Marina P. Shevelyova, Vasiliy I. Vladimirov, Michelle F. Buyanova, Dmitry V. Zinchenko, Andrey A. Zamyatnin, François Devred, Andrey V. Golovin, Sergei E. Permyakov, Evgeni Yu. Zernii
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous system and retinal neurons, where it regulates many vital processes such as synaptic transmission. It coordinates three calcium ions by EF-hands 2-4, thereby tra
Externí odkaz:
https://doaj.org/article/ecff2bbad9074ec5bbe551fbff15b38f
Autor:
Viktoriia E. Baksheeva, Veronika V. Tiulina, Elena N. Iomdina, Sergey Yu. Petrov, Olga M. Filippova, Nina Yu. Kushnarevich, Elena A. Suleiman, Rémi Eyraud, François Devred, Marina V. Serebryakova, Natalia G. Shebardina, Dmitry V. Chistyakov, Ivan I. Senin, Vladimir A. Mitkevich, Philipp O. Tsvetkov, Evgeni Yu. Zernii
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2023, 24 (7132), ⟨10.3390/ijms24087132⟩
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7132
International Journal of Molecular Sciences, 2023, 24 (7132), ⟨10.3390/ijms24087132⟩
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7132
International audience; Primary open-angle glaucoma (POAG) is a frequent blindness-causing neurodegenerative disorder characterized by optic nerve and retinal ganglion cell damage most commonly due to a chronic increase in intraocular pressure. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e660e2000867dc9fd73c854a1bdcb7
https://hal-amu.archives-ouvertes.fr/hal-04066064
https://hal-amu.archives-ouvertes.fr/hal-04066064
Autor:
Dahbia Yatoui, Philipp O. Tsvetkov, Romain La Rocca, Viktoriia E. Baksheeva, Diane Allegro, Gilles Breuzard, Géraldine Ferracci, Deborah Byrne, François Devred
Publikováno v:
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2022, 223, pp.1223-1229. ⟨10.1016/j.ijbiomac.2022.11.060⟩
International Journal of Biological Macromolecules, 2022, 223, pp.1223-1229. ⟨10.1016/j.ijbiomac.2022.11.060⟩
International audience; Tau is a naturally disordered microtubule associated protein which forms intraneuronal aggregates in several neurodegenerative diseases including Alzheimer disease (AD). It was reported that zinc interaction with tau protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35019fe20f98a13d4a6ef6edc5e6a02a
https://hal-amu.archives-ouvertes.fr/hal-03864881/document
https://hal-amu.archives-ouvertes.fr/hal-03864881/document
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178933 (2017)
Abundant regulatory 14-3-3 proteins have an extremely wide interactome and coordinate multiple cellular events via interaction with specifically phosphorylated partner proteins. Notwithstanding the key role of 14-3-3/phosphotarget interactions in man
Externí odkaz:
https://doaj.org/article/6fdbf4b1037348cd908c523527a3c6c4