Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Philipp M. Guenzl"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67013 (2013)
Sepsis still remains a major cause for morbidity and mortality in patients. The molecular mechanisms underlying the disease are still enigmatic. A great number of therapeutic approaches have failed and treatment strategies are limited to date. Among
Externí odkaz:
https://doaj.org/article/b6cb60e602e94748aeca94598049f074
Autor:
Martha V Koerner, Florian M Pauler, Quanah J Hudson, Federica Santoro, Anna Sawicka, Philipp M Guenzl, Stefan H Stricker, Yvonne M Schichl, Paulina A Latos, Ruth M Klement, Katarzyna E Warczok, Jacek Wojciechowski, Christian Seiser, Robert Kralovics, Denise P Barlow
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002540 (2012)
A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited chromosomes. In addition to being modified on maternally inherited chromosomes by a DNA meth
Externí odkaz:
https://doaj.org/article/101388fd6d6d45abbce01052c01e8d80
Autor:
Katja Parapatics, Robert Kralovics, Ferran Fece de la Cruz, Tilmann Bürckstümmer, Florian M. Pauler, Claudia Kerzendorfer, Richard Schobesberger, Philipp M. Guenzl, Jacques Colinge, Sylvia Knapp, Gustav Ammerer, Vincent A. Blomen, Barbara B. Maier, Carina Banning, Keiryn L. Bennett, Melissa Liszt, Tomasz Konopka, Wolfgang Fischl, M Rita Taba Casari, Philipp Hainzl, Michal Smida, Sejla Salic, Ana Lapao, Georg Casari, Christoph Bock, Johannes Stöckl, Benjamin Eizinger, Doris Chen, Bianca V. Gapp, Manuele Rebsamen, Thijn R. Brummelkamp, Giulio Superti-Furga, Sebastian M.B. Nijman, Fiorella Schischlik, Nicole C.C. Them
Knockout collections are invaluable tools for studying model organisms such as yeast. However, there are no large-scale knockout collections of human cells. Using gene-trap mutagenesis in near-haploid human cells, we established a platform to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7533ddac3be5058b432f6c7a5f0bcb
https://ora.ox.ac.uk/objects/uuid:64ba4455-e427-49bf-9273-12e27fa7eaa8
https://ora.ox.ac.uk/objects/uuid:64ba4455-e427-49bf-9273-12e27fa7eaa8
Autor:
Daniel, Andergassen, Christoph P, Dotter, Tomasz M, Kulinski, Philipp M, Guenzl, Philipp C, Bammer, Denise P, Barlow, Florian M, Pauler, Quanah J, Hudson
Publikováno v:
Nucleic Acids Research
Detecting allelic biases from high-throughput sequencing data requires an approach that maximises sensitivity while minimizing false positives. Here, we present Allelome.PRO, an automated user-friendly bioinformatics pipeline, which uses high-through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0884cb805f9e408a634a4b2573661b96
https://pubmed.ncbi.nlm.nih.gov/26202974
https://pubmed.ncbi.nlm.nih.gov/26202974
Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern
Autor:
Tomasz M, Kulinski, M Rita T, Casari, Philipp M, Guenzl, Daniel, Wenzel, Daniel, Andergassen, Anastasiya, Hladik, Paul, Datlinger, Matthias, Farlik, H-Christian, Theussl, Josef M, Penninger, Sylvia, Knapp, Christoph, Bock, Denise P, Barlow, Quanah J, Hudson
Publikováno v:
Developmental Biology
A large subset of mammalian imprinted genes show extra-embryonic lineage (EXEL) specific imprinted expression that is restricted to placental trophectoderm lineages and to visceral yolk sac endoderm (ysE). Isolated ysE provides a homogenous in vivo m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3547f316f8b98039f6221e03aebb567b
https://pubmed.ncbi.nlm.nih.gov/25912690
https://pubmed.ncbi.nlm.nih.gov/25912690
Publikováno v:
BMC Biology
Long non-protein-coding RNAs (lncRNAs) are proposed to be the largest transcript class in the mouse and human transcriptomes. Two important questions are whether all lncRNAs are functional and how they could exert a function. Several lncRNAs have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b05a367103d8100e5ef7b27d6f0079
https://doi.org/10.1186/1741-7007-11-59
https://doi.org/10.1186/1741-7007-11-59
Autor:
Denise P. Barlow, Philipp M. Guenzl
Publikováno v:
RNA biology. 9(6)
In the past ten years, long non-protein-coding RNAs (lncRNAs) have been shown to comprise a major part of the mammalian transcriptome and are predicted from their highly specific expression patterns, to play a role in regulating protein-coding gene e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f474fbeded3629b7b398a65f13602f5
https://pubmed.ncbi.nlm.nih.gov/22617879
https://pubmed.ncbi.nlm.nih.gov/22617879
Autor:
Markus Jaritz, Philipp M. Guenzl, Irena Vlatkovic, Ru Huang, Hendrik Marks, Ido Tamir, Hendrik G. Stunnenberg, Denise P. Barlow, Andreas Sommer, Robert Kralovics, Thorsten Klampfl, Florian M. Pauler
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27288 (2011)
PLoS ONE
PLoS One, 6, 11
PLoS One, 6
PLoS ONE
PLoS One, 6, 11
PLoS One, 6
Imprinted macro non-protein-coding (nc) RNAs are cis-repressor transcripts that silence multiple genes in at least three imprinted gene clusters in the mouse genome. Similar macro or long ncRNAs are abundant in the mammalian genome. Here we present t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264a40e810f45c7873ce5e53c1a3449d
http://europepmc.org/articles/PMC3213133?pdf=render
http://europepmc.org/articles/PMC3213133?pdf=render
Autor:
Aleksandra E. Kornienko, Christoph P. Dotter, Philipp M. Guenzl, Florian M. Pauler, Heinz Gisslinger, Robert Kralovics, Denise P. Barlow, Bettina Gisslinger, Ciara Cleary
Publikováno v:
Genome Biology
Background Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators and may ultimately be more numerous than protein-coding genes in the human genome. Despite large numbers of reported lncRNAs, reference annotations are likely in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece10fa3d2d3802a9645261567555a79