Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Philipp J. Jost"'
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia
Autor:
Veronika Dill, Kilian Kirmes, Jiaying Han, Melissa Klug, Marc Rosenbaum, Giacomo Viggiani, Moritz von Scheidt, Markus List, Peter Herhaus, Jürgen Ruland, Florian Bassermann, Karl-Ludwig Laugwitz, Katharina S. Götze, Philipp J. Jost, Stefanie Jilg, Conor J. Bloxham, Philip W.J. Raake, Isabell Bernlochner, Dario Bongiovanni
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Thromboembolic events are common in patients with essential thrombocythemia (ET). However, the pathophysiological mechanisms underlying the increased thrombotic risk remain to be determined. Here, we perform the first phenotypical characterization of
Externí odkaz:
https://doaj.org/article/6b03b9ff955e40ae9ff5ee319c518d34
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types for proteogenomi
Externí odkaz:
https://doaj.org/article/1b677a5e3e974d68b06b73bc60798d1c
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6cae0f5158ae4314ac4ec8b239aa4306
Autor:
Dominik A. Barth, Stefanie Stanzer, Jasmin Spiegelberg, Thomas Bauernhofer, Gudrun Absenger, Florian Posch, Rainer Lipp, Michael Halm, Joanna Szkandera, Marija Balic, Armin Gerger, Maria A. Smolle, Georg C. Hutterer, Christiane Klec, Philipp J. Jost, Julia Kargl, Martin Stradner, Martin Pichler
Publikováno v:
Cancer Medicine, Vol 11, Iss 16, Pp 3074-3083 (2022)
Abstract Background The presence of autoantibodies in the serum of cancer patients has been associated with immune‐checkpoint inhibitor (ICI) therapy response and immune‐related adverse events (irAEs). A prospective evaluation of different autoan
Externí odkaz:
https://doaj.org/article/8914eb1a50484886b516dc8999f59708
Autor:
Lea Baumgart, Melanie Barz, Claire Delbridge, Amir Kaywan Aftahy, Insa Katrin Janssen, Philipp J. Jost, Yu-Mi Ryang, Bernhard Meyer, Jens Gempt
Publikováno v:
Current Oncology, Vol 29, Iss 9, Pp 6236-6244 (2022)
(1) Background: Plasma cell neoplasia can be separated into independent subtypes including multiple myeloma (MM) and solitary plasmacytoma of the bone (SBP). The first clinical signs patients present with are skeletal pain, most commonly involving ri
Externí odkaz:
https://doaj.org/article/5889ef0ee44c46429c79925f643bc16e
Autor:
Lars Buschhorn, Dorett I. Odoni, Johanna Geuder, Timo O. Odinius, Celina V. Wagner, Stefanie Jilg, Ulrike Höckendorf, Adam Wahida, Matthias Schlesner, Andreas Reiter, Mohamad Jawhar, Philipp J. Jost
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/bc1a15f1f759423bb9cf447e09be5ed2
Autor:
Melanie Barz, Kaywan Aftahy, Insa Janssen, Yu-Mi Ryang, Georg Prokop, Stephanie E. Combs, Philipp J. Jost, Bernhard Meyer, Jens Gempt
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3891-3899 (2021)
Manifestation of malignant lymphoma in the spine is rare; there have only been a few cases reported in the literature. Due to its rarity, there is no gold standard for the management of patients suffering from spinal lymphoma manifestations. Methods:
Externí odkaz:
https://doaj.org/article/03fcf86e1a6a4a119cedf9d3f25951fd
Autor:
Michela Carlet, Kerstin Völse, Jenny Vergalli, Martin Becker, Tobias Herold, Anja Arner, Daniela Senft, Vindi Jurinovic, Wen-Hsin Liu, Yuqiao Gao, Veronika Dill, Boris Fehse, Claudia D. Baldus, Lorenz Bastian, Lennart Lenk, Denis M. Schewe, Johannes W. Bagnoli, Binje Vick, Jan Philipp Schmid, Alexander Wilhelm, Rolf Marschalek, Philipp J. Jost, Cornelius Miething, Kristoffer Riecken, Marc Schmidt-Supprian, Vera Binder, Irmela Jeremias
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Preclinical molecular models are useful that mimic a patient´s response to targeted therapy. Here, the authors establish an in vivo inducible RNAi-mediated gene silencing system in patient-derived xenograft models of acute leukemia to identify indiv
Externí odkaz:
https://doaj.org/article/6e797a213a574904a9cff02ded829844
Autor:
Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: The treatment landscape of metastatic renal cell carcinoma (mRCC) has substantially advanced over the last three decades, whereby data from controlled clinical trials indicate significant improvements regarding patients’ overall surviva
Externí odkaz:
https://doaj.org/article/1ad8615ac9ab434590e72d3eae997bc7
Autor:
Florian Posch, Tobias Niedrist, Theresa Glantschnig, Saskia Firla, Florian Moik, Ewald Kolesnik, Markus Wallner, Nicolas Verheyen, Philipp J. Jost, Andreas Zirlik, Martin Pichler, Marija Balic, Peter P. Rainer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Background/PurposeThis study aims to quantify the utility of monitoring LVEF, hs-cTnT, and NT-proBNP for dynamic cardiotoxicity risk assessment in women with HER2+ early breast cancer undergoing neoadjuvant/adjuvant trastuzumab-based therapy.Material
Externí odkaz:
https://doaj.org/article/9d447758d7e1408a908b0b606cfc1778