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pro vyhledávání: '"Philipp J. Heckmeier"'
Autor:
Philipp J. Heckmeier, Dieter Langosch
Publikováno v:
Biochemistry. 60:2457-2462
Green fluorescent protein (GFP) and related fluorescent proteins have multiple applications in cell biology, and elucidating their functions has been at the focus of biophysical research for about three decades. Fluorescent proteins can be bleached b
Publikováno v:
Journal of molecular biology. 434(17)
The protein MCL-1 is a crucial factor in regulating apoptosis, the programmed cell death, and thus plays a major role in numerous cancer types. The allosteric protein MCL-1 is naturally moderated by the BH3-only peptide BIM, which binds at its canoni
A stop-flow sample delivery system for transient spectroscopy is presented, which is, in particular, suited for laser-based instruments (quantum-cascade lasers or amplified femtosecond lasers) with excitation pulse repetition rates in the range 10–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807b6692b6f3356d9ab1b7615ab52520
Autor:
Ralf Stehle, Maria Hoyer, Dieter Langosch, Don C. Lamb, Mark G. Teese, Ganesh Agam, Philipp J. Heckmeier
Publikováno v:
Biophys J
Biophys. J. 119, 99-114 (2020)
Biophys. J. 119, 99-114 (2020)
A large fraction of soluble and membrane-bound proteins exists as non-covalent dimers, trimers, and higher-order oligomers. The experimental determination of the oligomeric state or stoichiometry of proteins remains a nontrivial challenge. In one app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c12ed576f5a776738a9058f99fa148
https://europepmc.org/articles/PMC7335908/
https://europepmc.org/articles/PMC7335908/
Publikováno v:
Biophysical Journal. 112:452a-453a
Protein-protein interactions are the fundamental driving force of numerous cellular processes and cell signaling pathways. Characterizing whether proteins interact as dimers, trimers, or higher oligomers is essential to understanding these interactio
Publikováno v:
Biophysical Journal. 110:395a-396a
Using genetic reporter assays, significant self-interaction has been discovered in over 50 transmembrane (TM) helices from single-pass membrane proteins. To understand the biological functions of these TM interactions, which include signal transfer a