Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Philipp Hegner"'
Autor:
Philipp Hegner, Florian Ofner, Benedikt Schaner, Mathias Gugg, Maximilian Trum, Anna-Maria Lauerer, Lars Siegfried Maier, Michael Arzt, Simon Lebek, Stefan Wagner
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundObstructive sleep apnea (OSA) has been linked to various pathologies, including arrhythmias such as atrial fibrillation. Specific treatment options for OSA are mainly limited to symptomatic approaches. We previously showed that increased pr
Externí odkaz:
https://doaj.org/article/cba623ba78e049099b17ba9e7cf9fe9b
Autor:
Anton Heller, Matthäus Zerdzitzki, Philipp Hegner, Zhiyang Song, Christian Schach, Florian Hitzenbichler, Kostiantyn Kozakov, Claudius Thiedemann, Zdenek Provaznik, Christof Schmid, Jing Li
Publikováno v:
Life, Vol 14, Iss 8, p 1029 (2024)
Background: Native (NVE) and prosthetic (PVE) aortic valve endocarditis (AVE) remain a surgical challenge with an ongoing trend towards more complex surgical procedures. Methods: First-time NVE was compared with PVE, focusing on pathogens, risk facto
Externí odkaz:
https://doaj.org/article/20b3c7c143ec42cea8e5a62861270bb5
Autor:
Maria Tafelmeier, Verka-Georgieva Blagoeva, Maximilian Trum, Philipp Hegner, Bernhard Floerchinger, Daniele Camboni, Marcus Creutzenberg, Florian Zeman, Christof Schmid, Lars Siegfried Maier, Stefan Wagner, Dominik Linz, Mathias Baumert, Michael Arzt
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2665 (2023)
Background: Nocturnal hypoxemia has been linked to increased cardiovascular morbidity and mortality. Several common diseases, such as sleep-disordered breathing (SDB), heart failure (HF), obesity, and pulmonary disease, coincide with an elevated noct
Externí odkaz:
https://doaj.org/article/7d281dcc07dd4f089964a08100a0cfa3
Autor:
Philipp Hegner, Simon Lebek, Benedikt Schaner, Florian Ofner, Mathias Gugg, Lars Siegfried Maier, Michael Arzt, Stefan Wagner
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 315 (2023)
Left ventricular contractile dysfunction and arrhythmias frequently occur in patients with sleep-disordered breathing (SDB). The CaMKII-dependent dysregulation of cellular Ca homeostasis has recently been described in SDB patients, but these studies
Externí odkaz:
https://doaj.org/article/dffcf27211ea4844a86250dd2c2266ef
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sleep apnea is a highly prevalent disorder with increasing impact on healthcare systems worldwide. Previous studies have been conducted primarily with male subjects, and prevalence and severity of sleep apnea in women are underestimated. Recent clini
Externí odkaz:
https://doaj.org/article/d0108ad2fce64051907b88a74e044834
Autor:
Philipp Hegner, Marzena Drzymalski, Alexander Biedermann, Bernadette Memmel, Melanie Durczok, Michael Wester, Bernhard Floerchinger, Zdenek Provaznik, Christof Schmid, York Zausig, Lars S. Maier, Stefan Wagner
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1932 (2022)
Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca2+ concentration in response to high intracellular Na+ levels, which may contribute to diastolic contractile dysfunction. Furthermore, increased sponta
Externí odkaz:
https://doaj.org/article/e8e11a5666a64d56aa6f189c8b32711f
Autor:
Simon Lebek, Philipp Hegner, Maria Tafelmeier, Leopold Rupprecht, Christof Schmid, Lars Siegfried Maier, Michael Arzt, Stefan Wagner
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objective: Sleep-disordered breathing (SDB) is a widespread disease that is often associated with heart failure (HF) with preserved ejection fraction (HFpEF). HFpEF is more frequent in women than in men, but detailed pathomechanisms remain unclear. W
Externí odkaz:
https://doaj.org/article/d341781d685447e4b19b4c6e1ae92f02
Autor:
Simon Lebek, Philipp Hegner, Christian Schach, Kathrin Reuthner, Maria Tafelmeier, Lars Siegfried Maier, Michael Arzt, Stefan Wagner
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243844 (2020)
AimsObstructive sleep apnea (OSA) is a widespread disease with high global socio-economic impact. However, detailed pathomechanisms are still unclear, partly because current animal models of OSA do not simulate spontaneous airway obstruction. We test
Externí odkaz:
https://doaj.org/article/e0cfb62000834f6189841a97ca8aa2d6
Autor:
Simon Lebek, Philipp Hegner, Rosa Hultsch, Jonas Rohde, Leopold Rupprecht, Christof Schmid, Samuel Sossalla, Lars Siegfried Maier, Michael Arzt, Stefan Wagner
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1428-1431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118de288421d0ee33b4060e8253a5b5a
https://doi.org/10.1164/rccm.202205-0981le
https://doi.org/10.1164/rccm.202205-0981le
Autor:
Maria Tafelmeier, Stefan Wagner, Simon Schopka, Christof Schmid, Daniele Camboni, Lars S. Maier, Michael Arzt, Simon Lebek, Philipp Hegner
Publikováno v:
Heart Rhythm. 18:2187-2194
Background Patients with atrial fibrillation (AF) exhibit decreased atrial expression of connexin (Cx), which has been causally linked to a proarrhythmogenic substrate. Interestingly, patients with sleep-disordered breathing (SDB) are at increased ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbe52d63948b72766feedea58ea8d5e
https://doi.org/10.1016/j.hrthm.2021.09.009
https://doi.org/10.1016/j.hrthm.2021.09.009