A Novel Echocardiographic Parameter to Confirm Low-Gradient Aortic Stenosis Severity

Autor: Sébastien Hecht, MSc, Mohamed-Salah Annabi, MD, MSc, Viktória Stanová, PhD, Abdellaziz Dahou, MD, PhD, Ian G. Burwash, MD, Matthias Koschutnik, MD, Philipp E. Bartko, MD, Jutta Bergler-Klein, MD, Julia Mascherbauer, MD, Carolina Donà, MD, Stefan Orwat, MD, Helmut Baumgartner, MD, Joao L. Cavalcante, MD, Henrique B. Ribeiro, MD, PhD, Alexis Théron, MD, PhD, Josep Rodes-Cabau, MD, Marie-Annick Clavel, DVM, PhD, Philippe Pibarot, DVM, PhD

Publikováno v: JACC: Advances, Vol 3, Iss 10, Pp 101245- (2024)

Background: In patients with low-gradient (LG) aortic stenosis (AS), confirming disease severity and indication of intervention often requires dobutamine stress echocardiography (DSE) or aortic valve calcium scoring by computed tomography. We hypothe

Externí odkaz: https://doaj.org/article/0eac25b0a61a4057ab82081eb7749b8a

PSMA-PET improves deep learning-based automated CT kidney segmentation

Autor: Julian Leube, Matthias Horn, Philipp E. Hartrampf, Andreas K. Buck, Michael Lassmann, Johannes Tran-Gia

Publikováno v: Zeitschrift für Medizinische Physik, Vol 34, Iss 2, Pp 231-241 (2024)

For dosimetry of radiopharmaceutical therapies, it is essential to determine the volume of relevant structures exposed to therapeutic radiation. For many radiopharmaceuticals, the kidneys represent an important organ-at-risk. To reduce the time requi

Externí odkaz: https://doaj.org/article/ef07118153d449c58da18898bd5eba11

Comparing Data Quality and Response Behavior Between Smartphone, Tablet, and Computer Devices in Responsive Design Online Surveys

Autor: Jean Philippe Décieux, Philipp E. Sischka

Publikováno v: SAGE Open, Vol 14 (2024)

Mobile device usage in online surveys has steadily increased in recent years. As mobile devices differ, for example, in their handling, from computers, device effects within online surveys are found for several data quality indicators. However, resul

Externí odkaz: https://doaj.org/article/01e69a1b9b754924b4f949c595c6f988

Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization

Autor: Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)

Abstract Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is un

Externí odkaz: https://doaj.org/article/6885cd75dd3641e481d840972315e815

Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial

Autor: Torben Hansen, Pere Ginès, Wim Laleman, Peer Bork, Vishal C Patel, Debbie Shawcross, Robert Schierwagen, Camila Alvarez-Silva, Florence Servant, Jonel Trebicka, Benjamin Lelouvier, Manimozhiyan Arumugam, Ed J Kuijper, Frank Erhard Uschner, Michael Praktiknjo, Mária Papp, Saeed Shoaie, Michael Kühn, Maja Thiele, Paolo Angeli, Joan Claria, Vicente Arroyo, Manolo Laiola, Benoit Quinquis, Sabine Klein, Minneke J Coenraad, François Fenaille, Debbie Lindsay Shawcross, Wenyi Gu, Adria Juanola, Elisa Pose, Aleksander Krag, Ivica Letunic, Alain Pruvost, Hervé M Blottière, Nathalie Galleron, Cristina López-Vicario, Peter V Treit, Matthias Mann, Jelle Matthijnssens, Mark J W Mcphail, Philipp E Geyer, Hans Olav Melberg, Stefanie Kandels, Cristina Sánchez-Garrido, Florence A Castelli, Christophe Junot, Lars Asphaug, Mads Israelsen, Helene Bæk Juel, Nikolaj Torp, Minneke Coenraad, Marko Korenjak, Ferran Aguilar-Parera, Patricia Sierra-Casas, Anna Bosch-Comas, David Tornai, Boglarka Balogh, Katrine Holtz Thorhauge, Casper Sahl Poulsen, Thea Van Rossum, Suguru Nishijima, Marisa I Keller, Diënty H M Hazenbrink, Sylvain Dechaumet, Sebastian D Burz, Emeline Chu-Van, Etienne Thévenot, Florian A Rosenberger, Sebastian Van Blerk, Amirouche Ouzerdine, Alain Roulet, Jean-Louis-Marie Insonere, Céline Serres, Mathieu Almeida, Florence Thirion, Camille Champion, Chaima Ezzine, Célia Chamignon, Nicolas Lapaque, Mamadou Gabou Thiam, Lore Van Espen, Quinten R Ducarmon, Annelotte GC Broekhoven, Susan Fischer, Romy Zwittink, Itziar De Lecuona, Giulio Rosati, Celia Fuentes-Chust, Arben Merkoçi, Massimo Urban, José Alfonso Marrugo-Ramirez, Ameli Schwalber, Lindsey Ann Edwards, Victoria Tatiana Kronsten, David Moyes, Azadeh Harzandi, Jordi Gratacós-Ginès, Martina Pérez-Guasch, Miriam Pellón, Bryan Contreras, Max Brol, Manfred Fobker, Renata Antonina Feuerborn

Publikováno v: BMJ Open, Vol 14, Iss 2 (2024)

Introduction Human albumin is used in the treatment of complications of cirrhosis. However, the use of long-term human albumin administration is costly and resource demanding for both patients and healthcare systems. A precision medicine approach wit

Externí odkaz: https://doaj.org/article/289f12a27d2047adb5cb758cb2809703