Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Philipp Drewe-Boß"'
Autor:
Jes-Niels Boeckel, Maximilian Möbius-Winkler, Marion Müller, Sabine Rebs, Nicole Eger, Laura Schoppe, Rewati Tappu, Karoline E. Kokot, Jasmin M. Kneuer, Susanne Gaul, Diana M. Bordalo, Alan Lai, Jan Haas, Mahsa Ghanbari, Philipp Drewe-Boss, Martin Liss, Hugo A. Katus, Uwe Ohler, Michael Gotthardt, Ulrich Laufs, Katrin Streckfuss-Bömeke, Benjamin Meder
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 1, Pp 129-146 (2022)
Alternative mRNA splicing is a fundamental process to increase the versatility of the genome. In humans, cardiac mRNA splicing is involved in the pathophysiology of heart failure. Mutations in the splicing factor RNA binding motif protein 20 (RBM20)
Externí odkaz:
https://doaj.org/article/1a62d499b1c84c03a1e970a9381d3d3a
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Accurate prediction of healthcare costs is important for optimally managing health costs. However, methods leveraging the medical richness from data such as health insurance claims or electronic health records are missing. Methods
Externí odkaz:
https://doaj.org/article/6e583c59a8f8411aa25823a2d1a529ea
Autor:
Karoline Holler, Anika Neuschulz, Philipp Drewe-Boß, Janita Mintcheva, Bastiaan Spanjaard, Roberto Arsiè, Uwe Ohler, Markus Landthaler, Jan Philipp Junker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Early stages of embryogenesis are known to depend on subcellular localization and transport of maternal mRNA, but systematic analyses have been hindered by a lack of methods for tracking of RNA. Here the authors combine spatially-resolved transcripto
Externí odkaz:
https://doaj.org/article/ccde7f9fb6194c37951752ef36e5cf99
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract CLIP-seq methods allow the generation of genome-wide maps of RNA binding protein – RNA interaction sites. However, due to differences between different CLIP-seq assays, existing computational approaches to analyze the data can only be appl
Externí odkaz:
https://doaj.org/article/fed1e40fc1db4685a5d9f0ac304a5a1a
Autor:
Jes-Niels Boeckel, Maximilian Nicolas Moebius-Winkler, Marion Müller, Sabine Rebs, Nicole Eger, Laura Schoppe, Rewatti Tappu, Karoline Elizabeth Kokot, Jasmin M Kneuer, Susanne Gaul, diana martins bordalo, alain lai, Jan Haas, Mahsa Ghanbari, Philipp Drewe-Boss, Martin Liss, Hugo A Katus, Uwe Ohler, Michael gotthardt, Ulrich Laufs, Katrin Streckfuß-Bömeke, Benjamin Meder
Publikováno v:
Circulation. 144
Introduction: The versatility of the human genome is increased by the process of alternative mRNA splicing. Impaired splicing of the cardiac transcriptome is involved in the pathophysiology of heart failure. Especially, mutations in cardiac-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08241a57da98d3fdd1ef18cdac5ed062
https://doi.org/10.1161/circ.144.suppl_1.10966
https://doi.org/10.1161/circ.144.suppl_1.10966
Autor:
Michael Gotthardt, Jes-Niels Boeckel, Mahsa Ghanbari, Maximilian Möbius-Winkler, Martin Liss, Jasmin M Kneuer, Uwe Ohler, Philipp Drewe-Boss, Sabine Rebs, Alan Lai, Katrin Streckfuss-Bömeke, Nicole Eger, Karoline E. Kokot, Laura Schoppe, Rewati Tappu, Jan Haas, Ulrich Laufs, Diana Martins Bordalo, Susanne Gaul, Marion Müller, Hugo A. Katus, Benjamin Meder
Publikováno v:
Genomics, proteomicsbioinformatics. 20(1)
Alternative mRNA splicing is a fundamental process to increase the versatility of the genome. In humans, cardiac mRNA splicing is involved in the pathophysiology of heart failure. Mutations in the splicing factor RNA binding motif protein 20 (RBM20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0214cff0aa9e1f069cccf5a9e6de90e6
https://pubmed.ncbi.nlm.nih.gov/34273561
https://pubmed.ncbi.nlm.nih.gov/34273561
Publikováno v:
Statistical methods in medical research. 29(12)
Objective We propose a data-driven method to detect temporal patterns of disease progression in high-dimensional claims data based on gradient boosting with stability selection. Materials and methods We identified patients with chronic obstructive pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9307dfde61fa1050865648abfef57d
https://pubmed.ncbi.nlm.nih.gov/32646307
https://pubmed.ncbi.nlm.nih.gov/32646307
Autor:
Philipp Drewe-Boss, Uwe Ohler, Florian Hinze, Markus Landthaler, Miha Milek, Michael Gotthardt
Publikováno v:
RNA biology. 15(3)
PAR-CLIP (photoactivatable ribonucleoside–enhanced crosslinking and immunoprecipitation) facilitates the identification and mapping of protein/RNA interactions. So far, it has been limited to select cell-lines as it requires efficient 4SU uptake. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df58ea0e07ee7dfe86c618bd0070dd89
https://pubmed.ncbi.nlm.nih.gov/29028411
https://pubmed.ncbi.nlm.nih.gov/29028411
High-throughput immunoprecipitation methods to analyze RNA binding protein – RNA in-teractions and modifications have great potential to further the understanding of post-tran-scriptional gene regulation. Due to the differences between individual a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1aa35ed0adbaadaacf33e553c7e2a4
https://doi.org/10.1101/161877
https://doi.org/10.1101/161877
Autor:
Jonas Behr, Sascha Geue, Philipp Drewe-Boß, André Kahles, Fabian H. Sinz, Andreas Wachter, Gunnar Rätsch, Lisa Hartmann, Gabriele Wagner, Dominik M Obermüller, Theresa Wießner, Hsin-Chieh Lee
Publikováno v:
The Plant cell. 28(11)
Plants use light as source of energy and information to detect diurnal rhythms and seasonal changes. Sensing changing light conditions is critical to adjust plant metabolism and to initiate developmental transitions. Here, we analyzed transcriptome-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e765c0fb4f2263422ca58a486717fe2
https://pubmed.ncbi.nlm.nih.gov/27956583
https://pubmed.ncbi.nlm.nih.gov/27956583