Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Philipp C, Münch"'
Autor:
Hüseyin Anil Gündüz, René Mreches, Julia Moosbauer, Gary Robertson, Xiao-Yin To, Eric A. Franzosa, Curtis Huttenhower, Mina Rezaei, Alice C. McHardy, Bernd Bischl, Philipp C. Münch, Martin Binder
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The success of deep learning in various applications depends on task-specific architecture design choices, including the types, hyperparameters, and number of layers. In computational biology, there is no consensus on the optimal architectur
Externí odkaz:
https://doaj.org/article/b554c98bf57c453fb229ac2d91814ba8
Autor:
Hüseyin Anil Gündüz, Martin Binder, Xiao-Yin To, René Mreches, Bernd Bischl, Alice C. McHardy, Philipp C. Münch, Mina Rezaei
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Deep learning in bioinformatics is often limited to problems where extensive amounts of labeled data are available for supervised classification. By exploiting unlabeled data, self-supervised learning techniques can improve the performance o
Externí odkaz:
https://doaj.org/article/b2573d0c664c4c8ab6a5d4fb3692c044
Autor:
Hüseyin Anil Gündüz, René Mreches, Julia Moosbauer, Gary Robertson, Xiao-Yin To, Eric A. Franzosa, Curtis Huttenhower, Mina Rezaei, Alice C. McHardy, Bernd Bischl, Philipp C. Münch, Martin Binder
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/705f653d3a0f409b9cf038c1de4cbd6e
Autor:
Stefanie Spriewald, Eva Stadler, Burkhard A. Hense, Philipp C. Münch, Alice C. McHardy, Anna S. Weiss, Nancy Obeng, Johannes Müller, Bärbel Stecher
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Colicins are toxins produced and released by Enterobacteriaceae to kill competitors in the gut. While group A colicins employ a division of labor strategy to liberate the toxin into the environment via colicin-specific lysis, group B colicin
Externí odkaz:
https://doaj.org/article/ab195971950f4951a7576465f9797849
Autor:
Claudia Eberl, Diana Ring, Philipp C. Münch, Markus Beutler, Marijana Basic, Emma Caroline Slack, Martin Schwarzer, Dagmar Srutkova, Anna Lange, Julia S. Frick, André Bleich, Bärbel Stecher
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
The Oligo-Mouse-Microbiota (OMM12) is a recently developed synthetic bacterial community for functional microbiome research in mouse models (Brugiroux et al., 2016). To date, the OMM12 model has been established in several germ-free mouse facilities
Externí odkaz:
https://doaj.org/article/766939abc9a44281bfa5b360fafd5642
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract This study describes the laboratory cultivation of ARMAN (Archaeal Richmond Mine Acidophilic Nanoorganisms). After 2.5 years of successive transfers in an anoxic medium containing ferric sulfate as an electron acceptor, a consortium was atta
Externí odkaz:
https://doaj.org/article/54555642c8f34a30b282b8e689a8cd4e
Autor:
Stéphane Hacquard, Barbara Kracher, Kei Hiruma, Philipp C. Münch, Ruben Garrido-Oter, Michael R. Thon, Aaron Weimann, Ulrike Damm, Jean-Félix Dallery, Matthieu Hainaut, Bernard Henrissat, Olivier Lespinet, Soledad Sacristán, Emiel Ver Loren van Themaat, Eric Kemen, Alice C. McHardy, Paul Schulze-Lefert, Richard J. O’Connell
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Colletotrichum tofieldiae is a beneficial root endophyte, whereas the closely related C. incanumis pathogenic. Here the authors compare the genomes and transcriptomes during host plant interaction and demonstrate that the host plant can respond diffe
Externí odkaz:
https://doaj.org/article/f8b45f63077a44869f87fc67e6e5bba4
Autor:
Philipp C. Münch, Lukas Bunse, Camila Fernández-Zapata, Josef Priller, Oliver Schnell, Sabine Heiland, Jürgen Beck, Edward W. Green, Chotima Böttcher, Denis Abu-Sammour, Francisco J. Quintana, Roman Sankowski, Felix Sahm, Carina Ramallo Guevara, Wolfgang Wick, Khwab Sanghvi, Tobias Kessler, Tim Trobisch, Frederik Cichon, Carsten Hopf, Lucas Schirmer, Michael Platten, Dieter Henrik Heiland, Miriam Ratliff, Anna von Landenberg, Theresa Bunse, Jana K. Sonner, Daniel Schrimpf, Mirco Friedrich, Marco Prinz, Hagen M. Gegner, Ilona Gutcher, Stefan Pusch, Michael Kilian, Gernot Poschet, Katrin Aslan, Markus Hahn, Andreas von Deimling
Publikováno v:
Nature cancer 2(7), 723-740 (2021). doi:10.1038/s43018-021-00201-z
The dynamics and phenotypes of intratumoral myeloid cells during tumor progression are poorly understood. Here we define myeloid cellular states in gliomas by longitudinal single-cell profiling and demonstrate their strict control by the tumor genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0e6be0c3c044ff5920726a9e65379e
https://doi.org/10.1038/s43018-021-00201-z
https://doi.org/10.1038/s43018-021-00201-z
Autor:
Martin Bendszus, Felix T. Kurz, Allen Alexander, Michael Platten, Frank Winkler, Michael O. Breckwoldt, Wolfgang Wick, Sabine Heiland, Matthia A. Karreman, Katrin Deumelandt, Philipp C. Münch, Kianush Karimian-Jazi, Manuel Piechutta, Manuel Fischer, Gergely Solecki, Mirco Friedrich, Kira Pfleiderer, Anna S. Berghoff
Publikováno v:
Theranostics
Rationale: Glioblastoma is the most frequent, primary brain tumor that is characterized by a highly immunosuppressive tumor microenvironment (TME). The TME plays a key role for tumor biology and the effectiveness of immunotherapies. Composition of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bda52493dfcf53f8f6ed707c30cb2b
https://doi.org/10.7150/thno.38659
https://doi.org/10.7150/thno.38659
Autor:
Achim Gass, Philipp C. Münch, Andreas von Deimling, Katharina Lindner, Josephine Kraus, Nima Etminan, Niko Engelke, Lukas Bunse, David E. Reuss, Mirco Friedrich, Christoph Groden, Michael Platten, Marc Fatar, Niklas Kehl, Iris Mildenberger
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
IgG4‐related disease (IgG4‐RD) is a fibroinflammatory disorder signified by aberrant infiltration of IgG4‐restricted plasma cells into a variety of organs. Clinical presentation is heterogeneous, and pathophysiological mechanisms of IgG4‐RD r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879a99d64e08eb817d7a802d58df0c36
https://doaj.org/article/2092b8d7df0b40dfac224be28ccddb6d
https://doaj.org/article/2092b8d7df0b40dfac224be28ccddb6d