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Autor:
Sebastian K. Eder, Philipp Ben Soussia, Milen Minkov, Florian Halbritter, Caroline Hutter, Andishe Attarbaschi, Raphaela Schwentner, Giulio Abagnale
Publikováno v:
Blood Advances. 6:970-975
Langerhans cell histiocytosis (LCH) is a neoplasm marked by the accumulation of CD1A+CD207+ cells. It is most commonly driven by a somatic, activating mutation in the BRAF serine-threonine kinase (BRAFV600E). Multisystem disease with risk-organ invol