Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Philipp A. Steffen"'
Autor:
Christina Altmutter, Attila Gyenesei, Leonie Ringrose, Philipp A. Steffen, Eva Dworschak, Xinzhou Zhu, Tobias Kockmann, Sini Junttila
Publikováno v:
Chromosoma
The Drosophila Trithorax group (TrxG) protein ASH1 remains associated with mitotic chromatin through mechanisms that are poorly understood. ASH1 dimethylates histone H3 at lysine 36 via its SET domain. Here, we identify domains of the TrxG protein AS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd7a906efa89968601279d73d2ec2d1
https://pubmed.ncbi.nlm.nih.gov/34331109
https://pubmed.ncbi.nlm.nih.gov/34331109
Publikováno v:
BioEssays. 34:901-913
How fast? How strong? How many? So what? Why do numbers matter in biology? Chromatin binding proteins are forever in motion, exchanging rapidly between bound and free pools. How do regulatory systems whose components are in constant flux ensure stabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a231a2fa9cdfd05ff28ea6515f96b3cc
https://doi.org/10.1002/bies.201200076
https://doi.org/10.1002/bies.201200076
Autor:
Philipp A. Steffen, Leonie Ringrose
Publikováno v:
Nature reviews. Molecular cell biology. 15(5)
In any biological system with memory, the state of the system depends on its history. Epigenetic memory maintains gene expression states through cell generations without a change in DNA sequence and in the absence of initiating signals. It is immense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40b72315f9aa1b8bbe4bc693464f197
https://pubmed.ncbi.nlm.nih.gov/24755934
https://pubmed.ncbi.nlm.nih.gov/24755934
Autor:
Philipp A. Steffen, Eva Dworschak, Cornelia Gänger, Leonie Ringrose, Tobias Kockmann, João Pedro Fonseca, Christian Beisel
Publikováno v:
Nucleic Acids Research, 41 (10)
Nucleic Acids Research
Nucleic Acids Research
The Polycomb (PcG) and Trithorax (TrxG) group proteins work antagonistically on several hundred developmentally important target genes, giving stable mitotic memory, but also allowing flexibility of gene expression states. How this is achieved in qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5be9d89a994b900247313f0a9bd5852
https://hdl.handle.net/20.500.11850/79597
https://hdl.handle.net/20.500.11850/79597
Autor:
Stefan Müller, Leonie Ringrose, James Lu, Christian Seiser, Philipp A. Steffen, Anna Sawicka, João Pedro Fonseca
Epigenetic memory mediated by Polycomb group (PcG) proteins must be maintained during cell division, but must also be flexible to allow cell fate transitions. Here we quantify dynamic chromatin-binding properties of PH::GFP and PC::GFP in living Dros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d67fd42ec925341d32169a0d6811c1
https://europepmc.org/articles/PMC3337459/
https://europepmc.org/articles/PMC3337459/
Publikováno v:
RNA biology. 6(2)
Non-coding RNAs regulate dosage compensation in mammals by controlling transcriptional silencing of one of the two X chromosomes in females. The two major transcripts involved in this process are Xist and its antisense counterpart Tsix. Expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61adfea97743d10e32abcb025679d850
https://pubmed.ncbi.nlm.nih.gov/19246991
https://pubmed.ncbi.nlm.nih.gov/19246991
Autor:
'Philipp A. Steffen
Publikováno v:
Christina Altmutter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::dec2b8df1208e382b957e5eca91661b2