Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Philipp A Pickerodt"'
Autor:
Philip von Platen, Philipp A. Pickerodt, Martin Russ, Mahdi Taher, Lea Hinken, Wolfgang Braun, Rainer Köbrich, Anake Pomprapa, Roland C. E. Francis, Steffen Leonhardt, Marian Walter
Publikováno v:
BioMedical Engineering OnLine, Vol 22, Iss 1, Pp 1-21 (2023)
Abstract Background Mechanical ventilation is an essential component in the treatment of patients with acute respiratory distress syndrome. Prompt adaptation of the settings of a ventilator to the variable needs of patients is essential to ensure per
Externí odkaz:
https://doaj.org/article/2e80bd9b8b894c7099c14c8d63cde4f3
Autor:
Emilia Boerger, Martin Russ, Philip von Platen, Mahdi Taher, Lea Hinken, Anake Pomprapa, Rainer Koebrich, Frank Konietschke, Jan Adriaan Graw, Burkhard Lachmann, Wolfgang Braun, Steffen Leonhardt, Philipp A. Pickerodt, Roland C. E. Francis
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background Models of hypoxemic lung injury caused by lavage-induced pulmonary surfactant depletion are prone to prompt recovery of blood oxygenation following recruitment maneuvers and have limited translational validity. We hypothesized tha
Externí odkaz:
https://doaj.org/article/261d3950f248465dbd699d6c23147a70
Autor:
Martin Russ, MD, Mario Menk, MD, Jan Adriaan Graw, MD, Vladimir Skrypnikov, MD, Oliver Hunsicker, MD, Kathleen Rudat, MD, Steffen Weber-Carstens, MD, Roland C. E. Francis, MD, Philipp A. Pickerodt, MD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 4, p e0671 (2022)
OBJECTIVES:. To investigate the ICU survival of venovenous extracorporeal membrane oxygenation (ECMO) patients suffering from COVID-19–related acute respiratory distress syndrome (ARDS) versus ECMO patients without COVID-19 (non-COVID-19)–related
Externí odkaz:
https://doaj.org/article/6f98d5fd53694330a0831cb3d154d182
Autor:
Steffen Weber-Carstens, Philipp A. Pickerodt, Jenelle Badulak, Martin Russ, Christoph Melzer-Gartzke, Elvira Steiner, Erik R. Swenson, Roland C. E. Francis, Thilo Busch, Willehad Boemke, Mahdi Taher
Publikováno v:
ASAIO Journal. 68:721-729
The contribution of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) to systemic oxygen delivery is determined by the ratio of total extracorporeal blood flow (Q˙EC) to cardiac output (Q˙). Thermodilution-based measurements of Q˙ may be
Autor:
Anake Pomprapa, Marian Walter, Mahdi Taher, Philipp A. Pickerodt, Arnhold Lohse, Roland C. E. Francis, Steffen Leonhardt, Philip von Platen, Emilia Boerger, Martin Russ
Publikováno v:
IFAC-PapersOnLine. 54:412-417
Optimizing the positive end-expiratory pressure remains challenging for any clinician treating a patient with acute respiratory distress syndrome. This paper presents an approach to automate a PEEP titration maneuver and identify the best PEEP accord
Autor:
Willehad Boemke, Adrián González-López, Philipp A. Pickerodt, Jan A. Graw, Mahdi Taher, Roland C. E. Francis, Lilly Veskemaa
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 320:L17-L28
Oxidative stress caused by mechanical ventilation contributes to the pathophysiology of ventilator-induced lung injury (VILI). A key mechanism maintaining redox balance is the upregulation of nuclear factor-erythroid-2-related factor 2 (Nrf2)-depende
Autor:
Marc Moritz Berger, Mahdi Sareban, Lisa Maria Schiefer, Kai E. Swenson, Franziska Treff, Larissa Schäfer, Peter Schmidt, Magdalena M. Schimke, Michael Paar, Josef Niebauer, Annalisa Cogo, Susi Kriemler, Stefan Schwery, Philipp A. Pickerodt, Benjamin Mayer, Peter Bärtsch, Erik R. Swenson
This randomized, placebo-controlled, double-blind study is the first to investigate whether acetazolamide, which reduces acute mountain sickness (AMS), inhibits short-term hypoxic pulmonary vasoconstriction, and also prevents high-altitude pulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e8e9a9a59d9252faa5dc4a60702bdb
https://doi.org/10.5167/uzh-227027
https://doi.org/10.5167/uzh-227027
Autor:
Burkhard Lachmann, Roland C. E. Francis, Mahdi Taher, Emilia Boerger, Martin Russ, Willehad Boemke, Philipp A. Pickerodt, Steffen Leonhardt, Philip von Platen
Publikováno v:
Journal of visualized experiments : JoVE. (170)
Various animal models exist to study the complex pathomechanisms of the acute respiratory distress syndrome (ARDS). These models include pulmo-arterial infusion of oleic acid, infusion of endotoxins or bacteria, cecal ligation and puncture, various p
Autor:
Willehad Boemke, Martin Russ, Steffen Weber-Carstens, Rainer Köbrich, Erik R. Swenson, T Busch, Mahdi Taher, Roland C. E. Francis, Philipp A. Pickerodt, Maria Deja, Moritz B. T. Hofferberth
Publikováno v:
Journal of Clinical Monitoring and Computing
Purpose Admixture of nitric oxide (NO) to the gas inspired with mechanical ventilation can be achieved through continuous, timed, or pulsed injection of NO into the inspiratory limb. The dose and timing of NO injection govern the inspired and intrapu
Autor:
Elvira Steiner, Willehad Boemke, Philipp A. Pickerodt, Adrián González-López, Martin Russ, Sebastian Kronfeldt, Thilo Busch, Katja Vorbrodt, Roland C. E. Francis, Philipp Lother, Erik R. Swenson
Publikováno v:
The Journal of Physiology. 597:1045-1058
Key points Carbonic anhydrase (CA) inhibitors such as acetazolamide inhibit hypoxic pulmonary vasoconstriction (HPV) in humans and other mammals, but the mechanism of this action remains unknown. It has been postulated that carbonic anhydrase may act