Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Philipp, Unberath"'
Autor:
Iryna Manuilova, Jan Bossenz, Annemarie Bianka Weise, Dominik Boehm, Cosima Strantz, Philipp Unberath, Niklas Reimer, Patrick Metzger, Thomas Pauli, Silke D Werle, Susann Schulze, Sonja Hiemer, Arsenij Ustjanzew, Hans A Kestler, Hauke Busch, Benedikt Brors, Jan Christoph
Publikováno v:
JMIR Research Protocols, Vol 13, p e58705 (2024)
BackgroundUnderstanding the similarities of patients with cancer is essential to advancing personalized medicine, improving patient outcomes, and developing more effective and individualized treatments. It enables researchers to discover important pa
Externí odkaz:
https://doaj.org/article/ee8f1cc375034ca5ac0d58a630db6022
Autor:
Dominik Boehm, Cosima Strantz, Jan Christoph, Hauke Busch, Thomas Ganslandt, Philipp Unberath
Publikováno v:
JMIR Research Protocols, Vol 13, p e53627 (2024)
BackgroundComplex and expanding data sets in clinical oncology applications require flexible and interactive visualization of patient data to provide the maximum amount of information to physicians and other medical practitioners. Interdisciplinary t
Externí odkaz:
https://doaj.org/article/851bfc64fade4f90a505c90909589fd4
Autor:
Christopher Renner, Niklas Reimer, Jan Christoph, Hauke Busch, Patrick Metzger, Melanie Boerries, Arsenij Ustjanzew, Dominik Boehm, Philipp Unberath
Publikováno v:
JMIR Medical Informatics, Vol 11, p e50017 (2023)
BackgroundIn molecular tumor boards (MTBs), patients with rare or advanced cancers are discussed by a multidisciplinary team of health care professionals. Software support for MTBs is lacking; in particular, tools for preparing and documenting MTB th
Externí odkaz:
https://doaj.org/article/bc23258d19c24846b4ee498076b1b64c
Autor:
Patrick Metzger, Maria Elena Hess, Andreas Blaumeiser, Thomas Pauli, Vincent Schipperges, Ralf Mertes, Jan Christoph, Philipp Unberath, Niklas Reimer, Raphael Scheible, Anna L. Illert, Hauke Busch, Geoffroy Andrieux, Melanie Boerries
Publikováno v:
Cancers, Vol 15, Iss 13, p 3456 (2023)
(1) Background: Next-generation sequencing (NGS) of patients with advanced tumors is becoming an established method in Molecular Tumor Boards. However, somatic variant detection, interpretation, and report generation, require in-depth knowledge of bo
Externí odkaz:
https://doaj.org/article/28bc27d4aeba4df6b71e8c0aca1f12cc
Autor:
Arsenij Ustjanzew, Alexander Desuki, Christoph Ritzel, Alina Corinna Dolezilek, Daniel-Christoph Wagner, Jan Christoph, Philipp Unberath, Thomas Kindler, Jörg Faber, Federico Marini, Torsten Panholzer, Claudia Paret
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Extensive sequencing of tumor tissues has greatly improved our understanding of cancer biology over the past years. The integration of genomic and clinical data is increasingly used to select personalized therapies in dedicated tu
Externí odkaz:
https://doaj.org/article/1fdb8149674344e5b4c3f22c5f6dc34d
Autor:
Boerries, Patrick Metzger, Maria Elena Hess, Andreas Blaumeiser, Thomas Pauli, Vincent Schipperges, Ralf Mertes, Jan Christoph, Philipp Unberath, Niklas Reimer, Raphael Scheible, Anna L. Illert, Hauke Busch, Geoffroy Andrieux, Melanie
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3456
(1) Background: Next-generation sequencing (NGS) of patients with advanced tumors is becoming an established method in Molecular Tumor Boards. However, somatic variant detection, interpretation, and report generation, require in-depth knowledge of bo
Searching of Clinical Trials Made Easier in cBioPortal Using Patients' Genetic and Clinical Profiles
Autor:
Philipp, Unberath, Lukas, Mahlmeister, Niklas, Reimer, Hauke, Busch, Melanie, Boerries, Jan, Christoph
Publikováno v:
Applied Clinical Informatics. 13:363-369
Background Molecular tumor boards (MTBs) cope with the complexity of an increased usage of genome sequencing data in cancer treatment. As for most of these patients, guideline-based therapy options are exhausted, finding matching clinical trials is c
Autor:
Philipp Buechner, Marc Hinderer, Philipp Unberath, Patrick Metzger, Martin Boeker, Till Acker, Florian Haller, Elisabeth Mack, Daniel Nowak, Claudia Paret, Denny Schanze, Nikolas von Bubnoff, Sebastian Wagner, Hauke Busch, Melanie Boerries, Jan Christoph
Publikováno v:
Diagnostics, Vol 10, Iss 2, p 93 (2020)
Clinicians in molecular tumor boards (MTB) are confronted with a growing amount of genetic high-throughput sequencing data. Today, at German university hospitals, these data are usually handled in complex spreadsheets from which clinicians have to ob
Externí odkaz:
https://doaj.org/article/6560c104b9294ebdbddf8687941359c4
Autor:
Johannes Vey, Lorenz A. Kapsner, Maximilian Fuchs, Philipp Unberath, Giulia Veronesi, Meik Kunz
Publikováno v:
Cancers, Vol 11, Iss 10, p 1606 (2019)
The identification of biomarker signatures is important for cancer diagnosis and prognosis. However, the detection of clinical reliable signatures is influenced by limited data availability, which may restrict statistical power. Moreover, methods for
Externí odkaz:
https://doaj.org/article/90ca9c9104fb47d3ad029c089f9744ed
Autor:
Niklas, Reimer, Philipp, Unberath, Hauke, Busch, Melanie, Börries, Patrick, Metzger, Arsenij, Ustjanzew, Christopher, Renner, Hans-Ulrich, Prokosch, Jan, Christoph
Publikováno v:
Studies in health technology and informatics. 287
In Molecular Tumor Boards (MTBs), therapy recommendations for cancer patients are discussed. To aid decision-making based on the patient's molecular profile, the research platform cBioPortal was extended based on users' requirements. Additionally, a