Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Philipp, Knopf"'
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Christian M. Seitz, Joerg Mittelstaet, Daniel Atar, Jana Hau, Selina Reiter, Clara Illi, Verena Kieble, Fabian Engert, Britta Drees, Giulia Bender, Ann-Christin Krahl, Philipp Knopf, Sarah Schroeder, Nikolas Paulsen, Alexander Rokhvarguer, Sophia Scheuermann, Elena Rapp, Anna-Sophia Mast, Armin Rabsteyn, Sabine Schleicher, Stefan Grote, Karin Schilbach, Manfred Kneilling, Bernd Pichler, Dominik Lock, Bettina Kotter, Sandra Dapa, Stefan Miltenyi, Andrew Kaiser, Peter Lang, Rupert Handgretinger, Patrick Schlegel
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Chimeric antigen receptor (CAR)-T therapy holds great promise to sustainably improve cancer treatment. However, currently, a broad applicability of CAR-T cell therapies is hampered by limited CAR-T cell versatility and tractability and the lack of ex
Externí odkaz:
https://doaj.org/article/856cb793555a4203b03dee394ed2e07f
Autor:
Christian M. Seitz, Sarah Schroeder, Philipp Knopf, Ann-Christin Krahl, Jana Hau, Sabine Schleicher, Manuela Martella, Leticia Quintanilla-Martinez, Manfred Kneilling, Bernd Pichler, Peter Lang, Daniel Atar, Karin Schilbach, Rupert Handgretinger, Patrick Schlegel
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Expression of the disialoganglioside GD2 has been identified as a marker antigen associated with a breast cancer stem-like cell (BCSC) phenotype. Here, we report on the evaluation of GD2 as a BCSC-specific target antigen for immunotherapy. GD2 expres
Externí odkaz:
https://doaj.org/article/2bde99f6251649b1b7d2e6a8cc1a4d9a
Autor:
Philipp Knopf, Manal O. Elnenaei, Mohamed Abou El Hassan, Julie Wagner, Shashi Gujar, Daniel Gaston, Barry E. Kennedy, Jeanette E. Boudreau, Clinton J. V. Campbell, Samuel D. Cutler, Andrea J. Thoni, Nicholas A. Forward, Darrell White, Marissa Goudie
Publikováno v:
The Journal of Molecular Diagnostics. 23:1699-1714
Multiple myeloma presents with numerous primary genomic lesions that broadly dichotomize cases into hyperdiploidy or IgH translocated. Clinically, these large alterations are assessed by fluorescence in situ hybridization (FISH) for risk stratificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc19ac31a32958294e3941b96a691736
https://doi.org/10.1016/j.jmoldx.2021.08.011
https://doi.org/10.1016/j.jmoldx.2021.08.011
Autor:
Manfred Kneilling, Dominik Sonanini, Philipp Knopf, Barbara F. Schörg, Christoph M. Griessinger, Klaus Dittmann, Martin Röcken, Bernd J. Pichler
Publikováno v:
Theranostics
CD4+ T helper cells are capable of mediating long-term antitumoral immune responses. We developed a combined immunotherapy (COMBO) using tumor antigen-specific T helper 1 cells (Tag-Th1), dual PD-L1/LAG-3 immune checkpoint blockade, and a low-dose to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3162d97489dd42e543ca5f5e6ddb88df
http://europepmc.org/articles/PMC8315067
http://europepmc.org/articles/PMC8315067
Autor:
Hubert Kalbacher, Johannes Schwenck, Andreas Maurer, Kamran Ghoreschi, Philipp Knopf, Thomas Reinheckel, Michael Gütschow, Daniel Bukala, Irene Gonzalez Menendez, Martin Schaller, Leticia Quintanilla-Martinez, Kerstin Fuchs, Stefan Laufer, Martin Röcken, Roman Mehling, Dennis Haupt, Birgit Fehrenbacher, Manfred Kneilling, Christoph M. Griessinger, Natalie Mucha, Bernd J. Pichler, Julia Holstein
Publikováno v:
Theranostics
Cysteine-type cathepsins such as cathepsin B are involved in various steps of inflammatory processes such as antigen processing and angiogenesis. Here, we uncovered the role of cysteine-type cathepsins in the effector phase of T cell-driven cutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20927f44dd5fabfd10101f96a7c9adf6
https://doi.org/10.7150/thno.31037
https://doi.org/10.7150/thno.31037
Autor:
Samuel D, Cutler, Philipp, Knopf, Clinton J V, Campbell, Andrea, Thoni, Mohamed, Abou El Hassan, Nicholas, Forward, Darrell, White, Julie, Wagner, Marissa, Goudie, Jeanette E, Boudreau, Barry E, Kennedy, Shashi, Gujar, Daniel, Gaston, Manal O, Elnenaei
Publikováno v:
The Journal of molecular diagnostics : JMD. 23(12)
Multiple myeloma presents with numerous primary genomic lesions that broadly dichotomize cases into hyperdiploidy or IgH translocated. Clinically, these large alterations are assessed by fluorescence in situ hybridization (FISH) for risk stratificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09d49443dd3b4cce7d71d79aa5bd5004
https://pubmed.ncbi.nlm.nih.gov/34562616
https://pubmed.ncbi.nlm.nih.gov/34562616
Autor:
Patrick Schlegel, Christian Seitz, Daniel Atar, Sarah Schroeder, Jana Hau, Leticia Quintanilla-Martinez, Manuela Martella, Rupert Handgretinger, Bernd J. Pichler, Philipp Knopf, Sabine Schleicher, Karin Schilbach, Ann-Christin Krahl, Peter Lang, Manfred Kneilling
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
Oncoimmunology
Expression of the disialoganglioside GD2 has been identified as a marker antigen associated with a breast cancer stem-like cell (BCSC) phenotype. Here, we report on the evaluation of GD2 as a BCSC-specific target antigen for immunotherapy. GD2 expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa11fa67d72214727f5a4d1b82710003
https://doaj.org/article/2bde99f6251649b1b7d2e6a8cc1a4d9a
https://doaj.org/article/2bde99f6251649b1b7d2e6a8cc1a4d9a
Autor:
Philipp Knopf
Mit der Neufassung des Geldwäschegesetzes (GwG) im Jahr 2017 als Folge der 4. EU-Geldwäscherichtlinie wurde das Transparenzregister im deutschen Recht festgeschrieben. Seit dem 01.10.2017 besteht für rechtsfähige Stiftungen, Vereine, Personenhand
Autor:
Philipp Knopf, Manal O. Elnenaei, Marissa Goudie, Andrea Thoni, Darrell White, Daniel Gaston, Nicholas Allen Forward, Samuel D. Cutler, Julie Wagner
Publikováno v:
Blood. 136:37-38
Introduction: Multiple Myeloma (MM) is the second most common hematological malignancy in North America. It is characterized by invasion of the bone marrow by malignant plasma cells. This malignancy presents with a broad range of primary genomic lesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd088d3159067ce517bca431054cd72
https://doi.org/10.1182/blood-2020-137754
https://doi.org/10.1182/blood-2020-137754