Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Philipp, Bengel"'
Autor:
Philipp Bengel, Nataliya Dybkova, Petros Tirilomis, Shakil Ahmad, Nico Hartmann, Belal A. Mohamed, Miriam Celine Krekeler, Wiebke Maurer, Steffen Pabel, Maximilian Trum, Julian Mustroph, Jan Gummert, Hendrik Milting, Stefan Wagner, Senka Ljubojevic-Holzer, Karl Toischer, Lars S. Maier, Gerd Hasenfuss, Katrin Streckfuss-Bömeke, Samuel Sossalla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In heart failure, increased CaMKII activity is decisively involved in arrhythmia formation. Here, the authors introduce the neuronal sodium channel NaV1.8 as a CaMKII downstream target as its specific knock-out reduces arrhythmias and improves surviv
Externí odkaz:
https://doaj.org/article/ba56cc69ae1140aebe506e2a3f9b30eb
Autor:
Axel Bauer, ProfMD, Nikolay Sappler, MD, Lukas von Stülpnagel, PhD, Mathias Klemm, MD, Michael Schreinlechner, MD, Felix Wenner, MD, Johannes Schier, MD, Amani Al Tawil, MSc, Theresa Dolejsi, MD, Aresa Krasniqi, MD, Elodie Eiffener, MSc, Christa Bongarth, MD, Markus Stühlinger, MD, Martin Huemer, MD, Tommaso Gori, ProfMD, Reza Wakili, ProfMD, Riza Sahin, MD, Robert Schwinger, MD, Matthias Lutz, MD, Armin Luik, MD, Nele Gessler, MD, Peter Clemmensen, ProfMD, Axel Linke, ProfMD, Lars S Maier, ProfMD, Martin Hinterseer, MD, Mathias C Busch, MD, Florian Blaschke, MD, Stefan Sack, ProfMD, Carsten Lennerz, MSc, Manuela Licka, MD, Roland R Tilz, ProfMD, Christian Ukena, MD, Joachim R Ehrlich, ProfMD, Markus Zabel, ProfMD, Georg Schmidt, ProfMD, Ulrich Mansmann, Prof, Stefan Kääb, ProfMD, Konstantinos D Rizas, MD, Steffen Massberg, ProfMD, Andreas May, Peter Seitzer, Roland Schmidt, Dritan Keta, Viktoria Janke, Christian Schläger, Elisabeth André, Niels Brandt, Alexandra Schön, Alfred Zollner, Luisa Freyer, Wolfgang Hamm, Johannes Beil, Anna Katharina Strüven, Anja Loew, Stephanie Fichtner, Philipp Lange, Aresa Krasniqi, Ulrich Grabmeier, Heidi Estner, Philipp Bengel, Lars Lüthje, Aleksandra Kirova, Thomas Fischer, Leonard Bergau, Jonas Herting, Simon Schlögl, Helge Haarmann, Klaudia Schlögl (Illes), Ekrem Uecer, Sabine Sag, Maria Tafelmeier, Carsten Jungbauer, Sabine Fredersdorf-Hahn, Christina Strack, Benedikt Seither, Joachim Seegers, Dominic Millenaar, Jan Wintrich, Patrick Fischer, Axel Buob, Amjad Razouk, Thomas Demming, Johanne Frank, Constantin Kühl, Ulrike Ellendt, Sarah Sandrock, Julia Gänsbacher, Janosch Cupa, Daniel Sinnecker, Karl-Ludwig Laugwitz, Alexander Steger, Anna Berkefeld, Karin Schinke, Petra Barthel, Michael Dommasch, Maiwand Amadei, Gerhard Hindricks, Danilo Obradovic, Michael Döring, Kerstin Bode, Sebastian Hilbert, Susanne Löbe, Helge Knopp, Sebastian König, Silke John, Katharina Schöne, Philipp Hartung, Christian Binner, Christine Meyer-Zürn, Martin Duckheim, Christian Eick, Fabian Simpfle, Jürgen Schreieck, Lars Mizera, Verena Tscholl, Lisa Steinbeck, Nadija Güc, Anne-Sophie Schatz, Philipp Attanasio, Andrea Heuberger, Mattias Roser, Barbara Bellmann, Patrick Nagel, Sebastian Biewener, Saba Suhail, Benjamin Juri, Christian Meyer, Stephan Wiilems, Christiane Jungen, Susanne Schmitt, Paula Münkerer, Julia Vogler, Lukas Kaiser, Benjamin Schäffer, Moritz Nies, Tobias Tönnis, Nina Fluschnik, Hanno Grahn, Christoph Waldeyer, Shinwan Kany, Nils Arne Sörensen, Simon Winkelmann, Özge Akbulak, Nils Arne Gosau, Tilman Würger, Natalie Arnold, Nele Geßler, Alexander Jobs, Paula Münkler, Stefan Rausch, Jelena Köster, Ben Brüggemann, Amr Abdin, Christian Wacker, Philipp Grotherr, Bastian Fries, Maximilian Faust, Stefanie Steuer, Patrick Swojanowsky, Stephan Willems, Nathaniel Portz, Amar Ujeyl, Matthias Krüger, Robert Gramlich, Till Köhler, Armin Sause, Ina Nover, Athanasios-Panagiotis Ziakos, Veaceslav Ciobanu, Norman Spelsberg, Johannes Siebermair, Amir-Abbas Mahabadi, Miriam Köhler, Nadine Vonderlin, Lisa Riesinger, Edison Abdiu, Anja Bachmann, Marie Frenzel, Astrid Hummel, Kristin Lehnert, Anne Krüger, Franke Busse, Andreas Napp, Dirk Müller-Wieland, Simone Battermann, Philipp Lacour, Tobias Trippel, Nick Lasse Beetz, Leonhard Schleußner, Veronika Zach, Christina Rozados, Harald Mudra, Stephan Staubach, Alexander Illmann, Michael Joner, Matthias Bock, Christof Kolb, Tobias Koch, Rebecca Fröhlich, Carsten Lennerz, Tobias Lenz, Patrick Fuchs, Markus Freißmuth, Christian Grebmer, Jürgen Kuschyk, Malte Kranert, Fabian Fastenrath, Gökhan Yücel, Boris Rudic, Sarah Würfel, Albrecht Römer, Andreas Böhmer, Jörg Honold, Stamatis Georgopoulos, Lukas Gleirscher, Susanne Lederle, Artem Chaplygin, Matthias Pauschinger, Andrea Brinker-Paschke, Jana Kropacek, Lars Eckardt, Christian Ellermann, Niklas Bode, Florian Reinke, Hauke Engelke, Robert Höllriegel, Felix Woitek, Ephraim Winzer, Karim Ibrahim, Christian Pflücke, Georg Ende, Uwe Speiser, Stephan Haußig, Rolf Wachter, Tobias Uhe, Torsten Konrad, Edgar Zitron, Jeton Destani, Fangyi Fu, Samer Al Said, Ziya Kaya, Wilfried Schgör, Thomas Senoner
Publikováno v:
The Lancet: Digital Health, Vol 4, Iss 2, Pp e105-e116 (2022)
Summary: Background: Cardiac autonomic dysfunction after myocardial infarction identifies patients at high risk despite only moderately reduced left ventricular ejection fraction. We aimed to show that telemedical monitoring with implantable cardiac
Externí odkaz:
https://doaj.org/article/92610b82bf4c49b598be13f614b421d3
Autor:
Philipp Bengel, Manar Elkenani, Bo E. Beuthner, Maik Pietzner, Belal A. Mohamed, Beatrix Pollok-Kopp, Ralph Krätzner, Karl Toischer, Miriam Puls, Andreas Fischer, Lutz Binder, Gerd Hasenfuß, Moritz Schnelle
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 95 (2023)
Severe aortic stenosis (AS) is a common pathological condition in an ageing population imposing significant morbidity and mortality. Based on distinct hemodynamic features, i.e., ejection fraction (EF), transvalvular gradient and stroke volume, four
Externí odkaz:
https://doaj.org/article/a4f86f85d7124ef2af6260cd4b28a390
Autor:
Gerd Hasenfuss, Klaudia Stella Schlögl, Markus Zabel, Helge Haarmann, Simon Schlögl, Philipp Bengel, Eva C.L. Rasenack, Leonard Bergau
Publikováno v:
Pacing and Clinical Electrophysiology. 45:14-22
BACKGROUND Data comparing remote magnetic catheter navigation (RMN) with manual catheter navigation (MCN) ablation of atrial fibrillation (AF) is lacking. The aim of the present prospective observational study was to compare the outcome of RMN versus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e42b930fe4fce97b1f69d99d0c7329
https://doi.org/10.1111/pace.14392
https://doi.org/10.1111/pace.14392
Autor:
Simon Schlögl, Klaudia Stella Schlögl, Philipp Bengel, Leonard Bergau, Helge Haarmann, Eva Rasenack, Gerd Hasenfuss, Markus Zabel
Publikováno v:
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 65(3)
Background In atrial fibrillation (AF) patients, catheter ablation of pulmonary veins (PVI) is the most effective therapeutic option to maintain sinus rhythm. To improve successful PVI, contact force–sensing (CF) catheters became routinely availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff94f7abe4fe4dd447f99725a537d921
https://pubmed.ncbi.nlm.nih.gov/35907108
https://pubmed.ncbi.nlm.nih.gov/35907108
Autor:
Leonard Bergau, Philipp Bengel, Vanessa Sciacca, Thomas Fink, Christian Sohns, Philipp Sommer
Publikováno v:
Journal of clinical medicine. 11(9)
Atrial fibrillation (AF) is the most common sustained arrhythmia worldwide and has a strong association with heart failure (HF). It often remains unclear if HF is the cause or consequence of AF due to the complexity of the processes that are involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31365b54c1c86387d381b36b4b6b4c49
https://pubmed.ncbi.nlm.nih.gov/35566639
https://pubmed.ncbi.nlm.nih.gov/35566639
Autor:
Philipp Bengel, Maximilian Trum, Samuel Sossalla, Gerd Hasenfuß, Shakil Ahmad, Nataliya Dybkova, Lars S. Maier, Stefan Wagner, P Tirilomis
Publikováno v:
Journal of Molecular and Cellular Cardiology. 144:35-46
Objective: In myocardial pathology such as heart failure a late sodium current (I-NaL) augmentation is known to be involved in conditions of arrhythmogenesis. However, the underlying mechanisms of the I-NaL generation are not entirely understood. By
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::809b62d683dcca36335442496305715d
https://doi.org/10.1016/j.yjmcc.2020.05.002
https://doi.org/10.1016/j.yjmcc.2020.05.002
Publikováno v:
GMDS
Automatic electrocardiogram (ECG) analysis has been one of the very early use cases for computer assisted diagnosis (CAD). Most ECG devices provide some level of automatic ECG analysis. In the recent years, Deep Learning (DL) is increasingly used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792e2d96a80edf552240113ad3053d49
https://doi.org/10.3233/shti210539
https://doi.org/10.3233/shti210539
Publikováno v:
Studies in health technology and informatics. 283
Automatic electrocardiogram (ECG) analysis has been one of the very early use cases for computer assisted diagnosis (CAD). Most ECG devices provide some level of automatic ECG analysis. In the recent years, Deep Learning (DL) is increasingly used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74f22bfffa45e15cdbe940643e8864af
https://pubmed.ncbi.nlm.nih.gov/34545818
https://pubmed.ncbi.nlm.nih.gov/34545818
Autor:
Stefan Wagner, Wiebke Maurer, Hendrik Milting, Nico Hartmann, Katrin Streckfuss-Bömeke, Julian Mustroph, Belal A. Mohamed, Maximilian Trum, P Tirilomis, Lars S. Maier, Karl Toischer, Miriam Celine Krekeler, Jan Gummert, Senka Ljubojevic-Holzer, Steffen Pabel, Gerd Hasenfuss, Samuel Sossalla, Nataliya Dybkova, Shakil Ahmad, Philipp Bengel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
An interplay between Ca2+/calmodulin-dependent protein kinase IIδc (CaMKIIδc) and late Na+ current (INaL) is known to induce arrhythmias in the failing heart. Here, we elucidate the role of the sodium channel isoform NaV1.8 for CaMKIIδc-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a8415f93078d89d557c95a0d79a40d