Výsledky vyhledávání - "Philip Y.-I. Choi"

A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

Autor: Christine S.M. Lee, Hai Po Helena Liang, David E. Connor, Agnibesh Dey, Ibrahim Tohidi-Esfahani, Heather Campbell, Shane Whittaker, David Capraro, Emmanuel J. Favaloro, Dea Donikian, Mayuko Kondo, Sarah M. Hicks, Philip Y.-I. Choi, Elizabeth E. Gardiner, Lisa Joanne Clarke, Huyen Tran, Freda H. Passam, Timothy Andrew Brighton, Vivien M. Chen

Publikováno v: Blood Advances. 6:3494-3506

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic complication of adenoviral vaccines, including the ChAdOx1 nCoV-19 (Vaxzevria) vaccine. The putative mechanism involves formation of pathological anti–platelet fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bbd3eb6e9b5ace699745667bd1d4a8
https://doi.org/10.1182/bloodadvances.2021006698

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Akademický článek

Immune thrombocytopenia: antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitro

Autor: Muna Iraqi, Jose Perdomo, Feng Yan, Philip Y-I Choi, Beng H. Chong

Publikováno v: Haematologica, Vol 100, Iss 5 (2015)

Primary immune thrombocytopenia is an autoimmune disease mediated by antiplatelet autoantibodies that cause platelet destruction and suppression of platelet production. In vitro effects of autoantibodies on megakaryocyte production and maturation hav

Externí odkaz: https://doaj.org/article/2d0dedf05edb41d5ab1db895c81e7163

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