Výsledky vyhledávání - "Philip Y. Paterson"

The enigma of oligoclonal immunoglobulin G in cerebrospinal fluid from multiple sclerosis patients

Autor: Caroline C. Whitacre, Philip Y. Paterson

Publikováno v: Immunology today. 2(6)

The cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) contains immunoglobulin G (IgG) of restricted heterogeneity (oligoclonal IgG). Philip Paterson and Caroline Whitacre here review the core evidence that IgG in MS patients and norm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f2f74b274f22ee4d3125a7498c09a8
https://pubmed.ncbi.nlm.nih.gov/25291659

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Potassium channel blockers inhibit adoptive transfer of experimental allergic encephalomyelitis by myelin-basic-protein-stimulated rat T lymphocytes

Autor: Jay Z. Yeh, Louise Pope Seifert, Philip Y. Paterson, Susan I.V. Judge, Mark D. Mannie

Publikováno v: Journal of Biomedical Science. 4:169-178

Agents which block T cell K(+) currents can prohibit both proliferative and effector cell functions in T cells activated by mitogens or phorbol esters. This study examined the effects of some of these blocking agents on the immune responsiveness of g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a0b65ac8166c2faf1a490ef6c28b19
https://doi.org/10.1007/bf02255646

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Antigen-specific inhibition of the adoptive transfer of experimental autoimmune enceophalomyelitis in Lewis rats

Autor: Stephen D. Miller, Philip Y. Paterson, Louise Pope

Publikováno v: Journal of Neuroimmunology. 37:177-189

The efficacy of antigen-specific immunoregulation as a treatment for the efferent limb of an autoimmune disease was tested in a rat model of adoptive experimental autoimmune encephalomyelitis (EAE). Lewis rats receiving 4–5 × 10 7 guinea pig (GP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262ea969ed969422f57888d208fdb8a8
https://doi.org/10.1016/0165-5728(92)90002-3

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Neurovascular fibrinolytic activity in normal Lewis rats and rats with cell-transferred experimental allergic encephalomyelitis

Autor: Philip Y. Paterson, Hau C. Kwaan, Chang-Sung Koh

Publikováno v: Journal of Neuroimmunology. 28:189-200

Fibrinolytic activity in the form of plasminogen activator (PA) was assessed using a histochemical fibrin slide technique in spinal cords of normal Lewis rats and rats with the cell-transferred from of experimental allergic encephalomyelitis (EAE). P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48664886c7149287eebbc6cdc37b258d
https://doi.org/10.1016/0165-5728(90)90012-c

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Modulation of Outward K(+) Conductance Is a Post-Activational Event in Rat T Lymphocytes Responsible for the Adoptive Transfer of Experimental Allergic Encephalomyelitis

Autor: Susan I.V. Judge, Mark D. Mannie, Jay Z. Yeh, Philip Y. Paterson

Publikováno v: Journal of biomedical science. 4(2-3)

Experimental allergic encephalomyelitis (EAE) is an accepted animal model for the human demyelinating disease multiple sclerosis. The continuously propagated line of Lewis rat T helper lymphocytes (GP1 T cells), specific for the encephalitogenic 68-8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4274d1f3b4617afacccf4293fafb6e
https://pubmed.ncbi.nlm.nih.gov/11725140

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Differential recognition of sequences within the encephalitogenic region of myelin basic protein capable of eliciting cell-mediated immune responses in experimental autoimmune encephalomyelitis

Autor: Michele K.H. Malotky, Philip Y. Paterson, Stephen D. Miller

Publikováno v: Journal of neuroimmunology. 51(1)

The fine specificity of myelin basic protein (MBP) epitopes capable of eliciting in vivo delayed-type hypersensitivity responses in Lewis rats with experimental autoimmune encephalomyelitis (EAE) was compared to those eliciting in vitro antigen-speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09b8c322febd00d19957a9562f496d3
https://pubmed.ncbi.nlm.nih.gov/7512576

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Concordance and localization of maximal vascular permeability change and fibrin deposition in the central neuraxis of Lewis rats with cell-transferred experimental allergic encephalomyelitis

Autor: Philip Y. Paterson, Chang-Sung Koh, John Gausas

Publikováno v: Journal of neuroimmunology. 38(1-2)

This study utilized Lewis rats and the cell-transfer form of experimental allergic encephalomyelitis (EAE) to focus on two central nervous system microvascular alterations known to be intimately associated with early clinical neurological signs of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf4977b4cef11a7d4a51f57bb7508fd
https://pubmed.ncbi.nlm.nih.gov/1577954

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