Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Philip Wing Lok Ho"'
Autor:
Jojo Yan Yan Kwok, Man Auyeung, Shirley Yin Yu Pang, Philip Wing Lok Ho, Doris Sau Fung Yu, Daniel Yee Tak Fong, Chia-chin Lin, Richard Walker, Samuel Yeung-shan Wong, Rainbow Tin Hung Ho
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Between 40 and 50% of patients with Parkinson’s disease (PD) experience anxiety and depression, associated with impaired physical function, high care dependency and mortality. Recently, the United States National Institutes of H
Externí odkaz:
https://doaj.org/article/df6db1af18e842b7b54718866732c8db
Autor:
Philip Wing-Lok Ho, Eunice Eun-Seo Chang, Chi-Ting Leung, Huifang Liu, Yasine Malki, Shirley Yin-Yu Pang, Zoe Yuen-Kiu Choi, Yingmin Liang, Weng Seng Lai, Yuefei Ruan, Kenneth Mei-Yee Leung, Susan Yung, Judith Choi-Wo Mak, Michelle Hiu-Wai Kung, David B. Ramsden, Shu-Leong Ho
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Parkinson’s disease (PD) is characterized by dopaminergic neurodegeneration in nigrostriatal and cortical brain regions associated with pathogenic α-synuclein (αSyn) aggregate/oligomer accumulation. LRRK2 hyperactivity is a disease-modif
Externí odkaz:
https://doaj.org/article/2e279dd54a294707af03424d9d6a60c0
Autor:
Eunice Eun Seo Chang, Philip Wing-Lok Ho, Hui-Fang Liu, Shirley Yin-Yu Pang, Chi-Ting Leung, Yasine Malki, Zoe Yuen-Kiu Choi, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-19 (2022)
Abstract Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are one of the most frequent genetic causes of both familial and sporadic Parkinson’s disease (PD). Mounting evidence has demonstrated pathological similarities between LRRK2-assoc
Externí odkaz:
https://doaj.org/article/06ce894a7bfb40c5b4c49bef2bb50a60
Autor:
Shirley Yin-Yu Pang, Rachel Cheuk Nam Lo, Philip Wing-Lok Ho, Hui-Fang Liu, Eunice Eun Seo Chang, Chi-Ting Leung, Yasine Malki, Zoe Yuen-Kiu Choi, Wing Yan Wong, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Mutations in leucine-rich repeat kinase 2 (LRRK2) and glucocerebrosidase (GBA) represent two most common genetic causes of Parkinson’s disease (PD). Both genes are important in the autophagic-lysosomal pathway (ALP), defects of which are a
Externí odkaz:
https://doaj.org/article/b6fc3201296c4ede996e68a53646446e
Autor:
Shirley Yin-Yu Pang, Philip Wing-Lok Ho, Hui-Fang Liu, Chi-Ting Leung, Lingfei Li, Eunice Eun Seo Chang, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-11 (2019)
Abstract Background Parkinson’s disease (PD) is characterized by dopaminergic neuronal loss in the substantia nigra pars compacta and intracellular inclusions called Lewy bodies (LB). During the course of disease, misfolded α-synuclein, the major
Externí odkaz:
https://doaj.org/article/43d50c8ae87c483988f526d2505c7897
Autor:
Philip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen‐Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi‐Ting Leung, Michelle Hiu‐Wai Kung, David Boyer Ramsden, Shu‐Leong Ho
Publikováno v:
Brain and Behavior. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af003f25166212b78be20a31c12d2afe
https://doi.org/10.1002/brb3.2886
https://doi.org/10.1002/brb3.2886
Autor:
null Philip Wing‐Lok Ho, null Lingfei Li, null Hui‐Fang Liu, null Zoe Yuen‐Kiu Choi, null Eunice Eun Seo Chang, null Shirley Yin‐Yu Pang, null Yasine Malki, null Chi‐Ting Leung, null Michelle Hiu‐Wai Kung, null David Boyer Ramsden, null Shu‐Leong Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea8f2b0aac0a3faff869235c11358e9d
https://doi.org/10.1002/brb3.2886/v2/response1
https://doi.org/10.1002/brb3.2886/v2/response1
Autor:
Hui-Fang Liu, Michelle Hiu-Wai Kung, Shirley Yin-Yu Pang, Philip Wing-Lok Ho, Eunice Eun Seo Chang, Chi-Ting Leung, Zoe Yuen-Kiu Choi, David B. Ramsden, Shu-Leong Ho
Publikováno v:
Autophagy. 17:3196-3220
Mitochondrial dysfunction causes energy deficiency and nigrostriatal neurodegeneration which is integral to the pathogenesis of Parkinson disease (PD). Clearance of defective mitochondria involves fission and ubiquitin-dependent degradation via mitop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86784a0cdfd18cbd8f168cfcabbf123
https://doi.org/10.1080/15548627.2020.1850008
https://doi.org/10.1080/15548627.2020.1850008
Autor:
Lingfei Li, Philip Wing-Lok Ho, Huifang Liu, Shirley Yin-Yu Pang, Eunice Eun-Seo Chang, Zoe Yuen-Kiu Choi, Yasine Malki, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3646
Synaptogyrin-3 (SYNGR3) is a synaptic vesicular membrane protein. Amongst four homologues (SYNGR1 to 4), SYNGR1 and 3 are especially abundant in the brain. SYNGR3 interacts with the dopamine transporter (DAT) to facilitate dopamine (DA) uptake and sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6f04533313c563993560da27274b29
Autor:
Eunice Eun Seo Chang, Philip Wing-Lok Ho, Hui-Fang Liu, Shirley Yin-Yu Pang, Chi-Ting Leung, Yasine Malki, Zoe Yuen-Kiu Choi, David Boyer Ramsden, Shu-Leong Ho
Publikováno v:
Translational neurodegeneration. 11(1)
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are one of the most frequent genetic causes of both familial and sporadic Parkinson’s disease (PD). Mounting evidence has demonstrated pathological similarities between LRRK2-associated PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b062f3d5b5ec698cb3071cb593f21a8
https://pubmed.ncbi.nlm.nih.gov/35152914
https://pubmed.ncbi.nlm.nih.gov/35152914