Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Philip Washbourne"'
Autor:
Denver Ncube, Alexandra Tallafuss, Jen Serafin, Joseph Bruckner, Dylan R. Farnsworth, Adam C. Miller, Judith S. Eisen, Philip Washbourne
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background An essential determinant of a neuron’s functionality is its neurotransmitter phenotype. We previously identified a defined subpopulation of cholinergic neurons required for social orienting behavior in zebrafish. Results We tran
Externí odkaz:
https://doaj.org/article/3544746cf6b74fd880047ff30e0523af
Autor:
Joseph J. Bruckner, Sarah J. Stednitz, Max Z. Grice, Dana Zaidan, Michelle S. Massaquoi, Johannes Larsch, Alexandra Tallafuss, Karen Guillemin, Philip Washbourne, Judith S. Eisen
Publikováno v:
PLoS Biology, Vol 20, Iss 11 (2022)
Host-associated microbiotas guide the trajectory of developmental programs, and altered microbiota composition is linked to neurodevelopmental conditions such as autism spectrum disorder. Recent work suggests that microbiotas modulate behavioral phen
Externí odkaz:
https://doaj.org/article/b82306f36ba94468a064a63714d9dc60
Autor:
Lucia Barazzuol, Domenico Cieri, Nicola Facchinello, Tito Calì, Philip Washbourne, Francesco Argenton, Paola Pizzo
Publikováno v:
Cells, Vol 12, Iss 3, p 376 (2023)
Mutations in presenilin 2 (PS2) have been causally linked to the development of inherited Alzheimer’s disease (AD). Besides its role as part of the γ-secretase complex, mammalian PS2 is also involved, as an individual protein, in a growing number
Externí odkaz:
https://doaj.org/article/d109659f437e4036a6c6316a27dba2fb
Autor:
Bernardo Blanco-Sánchez, Aurélie Clément, Sarah J Stednitz, Jennifer Kyle, Judy L Peirce, Marcie McFadden, Jeremy Wegner, Jennifer B Phillips, Ellen Macnamara, Yan Huang, David R Adams, Camilo Toro, William A Gahl, May Christine V Malicdan, Cynthia J Tifft, Erika M Zink, Kent J Bloodsworth, Kelly G Stratton, Undiagnosed Diseases Network, David M Koeller, Thomas O Metz, Philip Washbourne, Monte Westerfield
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009156 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008841.].
Externí odkaz:
https://doaj.org/article/27535b7c4ebd48a0a9b693598f19ae60
Autor:
Bernardo Blanco-Sánchez, Aurélie Clément, Sara J Stednitz, Jennifer Kyle, Judy L Peirce, Marcie McFadden, Jeremy Wegner, Jennifer B Phillips, Ellen Macnamara, Yan Huang, David R Adams, Camilo Toro, William A Gahl, May Christine V Malicdan, Cynthia J Tifft, Erika M Zink, Kent J Bloodsworth, Kelly G Stratton, Undiagnosed Diseases Network, David M Koeller, Thomas O Metz, Philip Washbourne, Monte Westerfield
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008841 (2020)
Hypomyelination, a neurological condition characterized by decreased production of myelin sheets by glial cells, often has no known etiology. Elucidating the genetic causes of hypomyelination provides a better understanding of myelination, as well as
Externí odkaz:
https://doaj.org/article/013d3575604347cf9f765d5b55ed4f6d
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205255 (2018)
During the process of synapse formation, thousands of proteins assemble at prospective sites of cell-cell communication. Although many of these proteins have been identified, the roles they play in generating functional connections during development
Externí odkaz:
https://doaj.org/article/37204ec07ef342ecb9be640a28424077
Autor:
Daniel K Fowler, Scott Stewart, Steve Seredick, Judith S Eisen, Kryn Stankunas, Philip Washbourne
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176543 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0159277.].
Externí odkaz:
https://doaj.org/article/c52fde7927cf4c0f8f65a9a76bed8250
Autor:
Bernardo Blanco-Sánchez, Aurélie Clément, Javier Fierro, Philip Washbourne, Monte Westerfield
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 5, Pp 547-559 (2014)
Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural deafness and progressive retinal degeneration. Mutations in several different genes produce USH, but the proximal cause of senso
Externí odkaz:
https://doaj.org/article/01fd30e51b1b4ad79ac80dc5f9d79e0f
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1199-1212 (2013)
Synapse formation is a complex process that involves the recruitment and assembly of a myriad of pre- and postsynaptic proteins. Despite being present at every synapse in the vertebrate CNS, little is known about the transport, recruitment, and stabi
Externí odkaz:
https://doaj.org/article/bce6f682a2f1455e85cb0a2fb44dff61
Autor:
Daniel K Fowler, Scott Stewart, Steve Seredick, Judith S Eisen, Kryn Stankunas, Philip Washbourne
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159277 (2016)
Recombination-based cloning is a quick and efficient way to generate expression vectors. Recent advancements have provided powerful recombinant DNA methods for molecular manipulations. Here, we describe a novel collection of three-fragment MultiSite
Externí odkaz:
https://doaj.org/article/6d29778bbe734c12b8a8d422e206c7e6