Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Philip W. Le Quesne"'
Natural product chemistry has undergone an explosive growth during the latter half of the current century. This has been brought about by a number of factors. One of these has been the growing number of sub stances from natural sources which displa
Autor:
Magdi M. Moussa, Philip W. Le Quesne
Publikováno v:
Tetrahedron Letters. 37:6479-6482
The total synthesis of pithomycolide 1 , a structurally unique ionophoric depsipeptide from the fungus Pithomyces chartarum , is described.
Autor:
Shao-Xia Yu, Philip W. Le Quesne
Publikováno v:
Tetrahedron Letters. 36:6205-6208
The total synthesis of (±) - funebral 5 , a sterically crowded, rotationally restricted pyrrole alkaloid, has been achieved by means of a new variation of the Paal-Knorr synthesis, employing titanium isopropoxide.
Publikováno v:
Natural Product Letters. 6:77-80
The characteristic metabolites of Quararibea funebris are based on (2S, 3S, 4R)-γ-hydroxyisoleucine, a hitherto rare amino acid. Two new stereoselective and efficient syntheses of this compound are described; one is based on Claisen chemistry and th
Autor:
Sheri L. Ablaza, Philip W. Le Quesne, Simon Bolvig, Ying Dong, David A. Forsyth, Shao-Xia Yu, Niranjan N. Pai
Publikováno v:
ChemInform. 30
Publikováno v:
ChemInform. 31
Autor:
Ying Dong, Philip W. Le Quesne
Publikováno v:
ChemInform. 33
Publikováno v:
The Journal of Organic Chemistry. 57:2100-2104
New synthetic sequences are described for 17β-hydroxy-1β,2β- and -1α,2α-epoxyestr-4-en-3-one, which are putative intermediates in the metabolism of estradiol to the 2,3- and 3,4-catecholestrogens, as well as the synthetic precursors of choice fo
Publikováno v:
Journal of natural products. 71(8)
The first enantiospecific total synthesis of (+)-alstonisine has been accomplished from D-tryptophan methyl ester 13 in 12% overall yield (in 17 reaction vessels). A diastereospecific osmylation process has been employed as a key step to convert indo
Publikováno v:
Tetrahedron Letters. 31:2681-2684
The first synthesis of (+) pseudophrynaminol, a unique pyrrolo [2,3b] indole recently isolated from the Australian frog Pseudophryne coriacea, is described.