Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Philip W. Connelly"'
Autor:
Ravi Retnakaran, Jiajie Pu, Anthony J. Hanley, Philip W. Connelly, Mathew Sermer, Bernard Zinman
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102363- (2024)
Summary: Background: The cardiometabolic implications of postprandial hyperinsulinemia are unclear with recent studies suggesting both adverse and beneficial associations. We aimed to evaluate the longitudinal cardiometabolic implications of the post
Externí odkaz:
https://doaj.org/article/7a7ac74a2e2947008c039d6f067c7af3
Autor:
Philip W. Connelly, Andrew T. Yan, Michelle M. Nash, Rachel M. Wald, Charmaine Lok, Lakshman Gunaratnam, Anish Kirpalani, G. V. Ramesh Prasad
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Patients on dialysis have impaired cardiac function, in part due to increased fluid volume and ventricular stress. Restored kidney function through transplantation reduces left ventricular volume in both systole and diastole. We previousl
Externí odkaz:
https://doaj.org/article/19f130a6c6e8491b8e58c2178de8ef7f
Autor:
Inna Y. Gong, Bandar Al-Amro, G. V. Ramesh Prasad, Philip W. Connelly, Rachel M. Wald, Ron Wald, Djeven P. Deva, Howard Leong-Poi, Michelle M. Nash, Weiqiu Yuan, Lakshman Gunaratnam, S. Joseph Kim, Charmaine E. Lok, Kim A. Connelly, Andrew T. Yan
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Cardiovascular disease is a significant cause of morbidity and mortality in patients with end-stage renal disease (ESRD) and kidney transplant (KT) patients. Compared with left ventricular (LV) ejection fraction (LVEF), LV strain
Externí odkaz:
https://doaj.org/article/77d0174ef592457daee7fef730c044a0
Autor:
Sadia Mehmood, Chang Ye, Philip W. Connelly, Anthony J. Hanley, Bernard Zinman, Ravi Retnakaran
Publikováno v:
Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract Background Gestational diabetes (GDM) and milder gestational impaired glucose tolerance (GIGT) identify women at risk of developing type 2 diabetes and cardiovascular disease later in life. Accordingly, the postpartum years after gestational
Externí odkaz:
https://doaj.org/article/6c06740c170d49868e3080b71c40aa64
Autor:
Xiaohong Ruby Xu, Yiming Wang, Reheman Adili, Lining Ju, Christopher M. Spring, Joseph Wuxun Jin, Hong Yang, Miguel A. D. Neves, Pingguo Chen, Yan Yang, Xi Lei, Yunfeng Chen, Reid C. Gallant, Miao Xu, Hailong Zhang, Jina Song, Peifeng Ke, Dan Zhang, Naadiya Carrim, Si-Yang Yu, Guangheng Zhu, Yi-Min She, Terry Cyr, Wenbin Fu, Guoqing Liu, Philip W. Connelly, Margaret L. Rand, Khosrow Adeli, John Freedman, Jeffrey E. Lee, Patrick Tso, Patrizia Marchese, W. Sean Davidson, Shaun P. Jackson, Cheng Zhu, Zaverio M. Ruggeri, Heyu Ni
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Activation of integrin αIIbβ3 at the surface of platelets is required for their aggregation and for thrombus formation. Here Xu et al. identify apolipoprotein A-IV as a novel ligand for platelet αIIbβ3 integrin, and find it inhibits platelet aggr
Externí odkaz:
https://doaj.org/article/0ce3127e01234b83a479b73aff61e66c
Autor:
Ravi Retnakaran, Chang Ye, Anthony J. Hanley, Philip W. Connelly, Mathew Sermer, Bernard Zinman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)
Background The 1‐hour glucose challenge test (GCT) is routinely performed in pregnancy to screen for gestational diabetes mellitus. Remarkably, it has recently emerged that the GCT can also predict a woman's future risk of cardiovascular disease, a
Externí odkaz:
https://doaj.org/article/e79e12d1aec44999afade4dab9ec34fe
Autor:
Sudaba Mansuri, Alaa Badawi, Sheena Kayaniyil, David E. Cole, Stewart B. Harris, Mary Mamakeesick, Thomas Wolever, Joel Gittelsohn, Jonathon L. Maguire, Philip W. Connelly, Bernard Zinman, Anthony J. Hanley
Publikováno v:
International Journal of Circumpolar Health, Vol 75, Iss 0, Pp 1-8 (2016)
Background: Sub-optimal vitamin D status is common worldwide and the condition may be associated with increased risk for various chronic diseases. In particular, low vitamin D status is highly prevalent in indigenous communities in Canada, although l
Externí odkaz:
https://doaj.org/article/9ea4cca005214c4ba6792ee127990acb
Autor:
G. V. Ramesh Prasad, Andrew T. Yan, Michelle M. Nash, S. Joseph Kim, Ron Wald, Rachel Wald, Charmaine Lok, Lakshman Gunaratnam, Gauri R. Karur, Anish Kirpalani, Philip W. Connelly
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 5 (2018)
Background: Cardiac magnetic resonance (CMR) imaging accurately and precisely measures left ventricular (LV) mass and function. Identifying mechanisms by which LV mass change and functional improvement occur in some end-stage kidney disease (ESKD) pa
Externí odkaz:
https://doaj.org/article/d5c0d9cf414d44b8a55f020e7fb3324a
Autor:
Piya Lahiry, Henian Cao, Matthew R. Ban, Rebecca L. Pollex, Mary Mamakeesick, Bernard Zinman, Stewart B. Harris, Anthony J.G. Hanley, Murray W. Huff, Philip W. Connelly, Robert A. Hegele
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 4, Pp 843-848 (2010)
Apolipoprotein (apo) C-I is a constituent of chylomicrons, very low density lipoprotein, and high density lipoprotein. The role of apo C-I in human metabolism is incompletely defined. We took advantage of a naturally occurring amino acid polymorphism
Externí odkaz:
https://doaj.org/article/20d928eb15f7486ca205a761e9c5a8c3
Autor:
Philip W. Connelly, Bernard Zinman, Graham F. Maguire, Mary Mamakeesick, Stewart B. Harris, Robert A. Hegele, Ravi Retnakaran, Anthony J.G. Hanley
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1216-1222 (2009)
Paraoxonase 1 (PON1) has been reported to be associated with proteinuria in subjects with type 2 diabetes mellitus (T2DM). Plasma cystatin C is more accurate than creatinine for identifying stage 3 kidney disease in T2DM. We tested the hypothesis tha
Externí odkaz:
https://doaj.org/article/2dba582ae1764a17b9790b86df3efe58